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View article: Consortium Author List from Cancer Research in the Age of Spatial Omics: Lessons from IMAXT
Consortium Author List from Cancer Research in the Age of Spatial Omics: Lessons from IMAXT Open
IMAXT Consortium Author List
View article: Data from Cancer Research in the Age of Spatial Omics: Lessons from IMAXT
Data from Cancer Research in the Age of Spatial Omics: Lessons from IMAXT Open
Summary:The Imaging and Molecular Annotation of Xenografts and Tumors Cancer Grand Challenges team was set up with the objective of developing the “next generation” of pathology and cancer research by using a combination of single-cell and…
View article: Consortium Author List from Cancer Research in the Age of Spatial Omics: Lessons from IMAXT
Consortium Author List from Cancer Research in the Age of Spatial Omics: Lessons from IMAXT Open
IMAXT Consortium Author List
View article: Imaging and Molecular Annotation of Xenographs and Tumours (IMAXT): High throughput data and analysis infrastructure
Imaging and Molecular Annotation of Xenographs and Tumours (IMAXT): High throughput data and analysis infrastructure Open
With the aim of producing a 3D representation of tumors, imaging and molecular annotation of xenografts and tumors (IMAXT) uses a large variety of modalities in order to acquire tumor samples and produce a map of every cell in the tumor an…
View article: Single-cell genomic variation induced by mutational processes in cancer
Single-cell genomic variation induced by mutational processes in cancer Open
How cell-to-cell copy number alterations that underpin genomic instability 1 in human cancers drive genomic and phenotypic variation, and consequently the evolution of cancer 2 , remains understudied. Here, by applying scaled single-cell w…
View article: Exploration and analysis of molecularly annotated, 3D models of breast cancer at single-cell resolution using virtual reality
Exploration and analysis of molecularly annotated, 3D models of breast cancer at single-cell resolution using virtual reality Open
A set of increasingly powerful approaches are enabling spatially resolved measurements of growing numbers of molecular features in biological samples. While important insights can be derived from the two-dimensional data that many of these…
View article: The Imaging and Molecular Annotation of Xenografts and Tumours (IMAXT) High Throughput Data and Analysis Infrastructure
The Imaging and Molecular Annotation of Xenografts and Tumours (IMAXT) High Throughput Data and Analysis Infrastructure Open
With the aim of producing a 3D representation of tumours, IMAXT uses a large variety of modalities in order to acquire tumour samples and produce a map of every cell in the tumour and its host environment. With the large volume and variety…
View article: Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems
Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems Open
Identifying transcript location in cells Identifying where specific RNAs occur within a cell or tissue has been limited by technology and imaging capabilities. Expansion microscopy has allowed for better visualization of small structures b…