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View article: Angry facial expressions elicit a late attentional withdrawal
Angry facial expressions elicit a late attentional withdrawal Open
Facial expressions of emotion are salient social cues that can trigger adaptive behavioral responses-such as facilitated approach or avoidance movements in response to positive or negative stimuli, respectively. We conducted a behavioral e…
View article: Olfactory Testing and Gray Matter Volume: A Combined Approach to Predict the Conversion to Alzheimer
Olfactory Testing and Gray Matter Volume: A Combined Approach to Predict the Conversion to Alzheimer Open
Background/Objectives: Olfactory decline is common in normal aging and frequent in neurodegenerative diseases such as Alzheimer’s disease (AD). Therefore, it has been suggested as a marker for the Mild Cognitive Impairment (MCI) progressio…
View article: Unveiling the Truth in Pain: Neural and Behavioral Distinctions Between Genuine and Deceptive Pain
Unveiling the Truth in Pain: Neural and Behavioral Distinctions Between Genuine and Deceptive Pain Open
Background/Objectives: Fake pain expressions are more intense, prolonged, and include non-pain-related actions compared to genuine ones. Despite these differences, individuals struggle to detect deception in direct tasks (i.e., when asked …
View article: Understanding basic and social emotions in Alzheimer's disease and frontotemporal dementia
Understanding basic and social emotions in Alzheimer's disease and frontotemporal dementia Open
Introduction Recent developments in the field of social cognition have led to a renewed interest in basic and social emotion recognition in early stages of Alzheimer's Disease (AD) and FrontoTemporal Dementia (FTD). Despite the growing att…
View article: Sensitivity and specificity of the action observation network to kinematics, target object, and gesture meaning
Sensitivity and specificity of the action observation network to kinematics, target object, and gesture meaning Open
Hierarchical models have been proposed to explain how the brain encodes actions, whereby different areas represent different features, such as gesture kinematics, target object, action goal, and meaning. The visual processing of action‐rel…
View article: Editorial: The brain in pain: a multidimensional approach
Editorial: The brain in pain: a multidimensional approach Open
Keywords: pain, empathy, Event-Related Potentials (ERPs), Near-InfraRed-Spectroscopy (NIRS), Magnetic Resonance Imaging (MRI), meta-analysis
View article: Effectiveness of patients’ involvement in a medical and nursing pain education programme: a protocol for an open-label randomised controlled trial including qualitative data
Effectiveness of patients’ involvement in a medical and nursing pain education programme: a protocol for an open-label randomised controlled trial including qualitative data Open
Introduction Pain is a multidimensional experience that varies among individuals and has a significant impact on their health. A biopsychosocial approach is recommended for effective pain management; however, health professionals’ educatio…
View article: Spatial attention modulation of the brain network involved in mental time travel.
Spatial attention modulation of the brain network involved in mental time travel. Open
As a result of the shift of spatial attention toward the left, the facilitation in having access to past events is associated with the inhibition of superior frontal gyrus in the left hemisphere, whereas the facilitation in projecting towa…
View article: Evaluation of an interprofessional education intervention in partnership with patient educators.
Evaluation of an interprofessional education intervention in partnership with patient educators. Open
The mean age of participants was 21±3.2 SD years and 76% were female. A paired t-test showed significant changes from before to after the IPE-PE in the mean total RIPLS score (42.7±5.8 SD vs 44.62±5.9 SD, P<0.001) and the mean total JSE-HP…
View article: Words hurt: common and distinct neural substrates underlying nociceptive and semantic pain
Words hurt: common and distinct neural substrates underlying nociceptive and semantic pain Open
Introduction Recent studies have shown that processing semantic pain, such as words associated with physical pain, modulates pain perception and enhances activity in regions of the pain matrix. A direct comparison between activations due t…
View article: “When You’re Smiling”: How Posed Facial Expressions Affect Visual Recognition of Emotions
“When You’re Smiling”: How Posed Facial Expressions Affect Visual Recognition of Emotions Open
Facial imitation occurs automatically during the perception of an emotional facial expression, and preventing it may interfere with the accuracy of emotion recognition. In the present fMRI study, we evaluated the effect of posing a facial …
View article: Neural correlates of emotional valence for faces and words
Neural correlates of emotional valence for faces and words Open
Stimuli with negative emotional valence are especially apt to influence perception and action because of their crucial role in survival, a property that may not be precisely mirrored by positive emotional stimuli of equal intensity. The ai…
View article: Can Disruption of Basal Ganglia-Thalamocortical Circuit in Wilson Disease Be Associated with Juvenile Myoclonic Epilepsy Phenotype?
Can Disruption of Basal Ganglia-Thalamocortical Circuit in Wilson Disease Be Associated with Juvenile Myoclonic Epilepsy Phenotype? Open
In this paper, we describe the multimodal MRI findings in a patient with Wilson disease and a seizure disorder, characterized by an electroclinical picture resembling juvenile myoclonic epilepsy. The brain structural MRI showed a depositio…
View article: Changes in Cancer Patients' and Caregivers' Disease Perceptions While Receiving Early Palliative Care: A Qualitative and Quantitative Analysis
Changes in Cancer Patients' and Caregivers' Disease Perceptions While Receiving Early Palliative Care: A Qualitative and Quantitative Analysis Open
Background Little is known about the underlying mechanisms through which early palliative care (EPC) improves multiple outcomes in patients with cancer and their caregivers. The aim of this study was to qualitatively and quantitatively ana…
View article: Different semantic and affective meaning of the words associated to physical and social pain in cancer patients on early palliative/supportive care and in healthy, pain-free individuals
Different semantic and affective meaning of the words associated to physical and social pain in cancer patients on early palliative/supportive care and in healthy, pain-free individuals Open
Early palliative/supportive care (ePSC) is a medical intervention focused on patient’s needs, that integrates standard oncological treatment, shortly after a diagnosis of advanced/metastatic cancer. ePSC improves the appropriate management…
View article: Pain Mirrors: Neural Correlates of Observing Self or Others’ Facial Expressions of Pain
Pain Mirrors: Neural Correlates of Observing Self or Others’ Facial Expressions of Pain Open
Facial expressions of pain are able to elicit empathy and adaptive behavioral responses in the observer. An influential theory posits that empathy relies on an affective mirror mechanism, according to which emotion recognition relies upon …
View article: Eight Weddings and Six Funerals: An fMRI Study on Autobiographical Memories
Eight Weddings and Six Funerals: An fMRI Study on Autobiographical Memories Open
"Autobiographical memory" (AM) refers to remote memories from one's own life. Previous neuroimaging studies have highlighted that voluntary retrieval processes from AM involve different forms of memory and cognitive functions. Thus, a comp…
View article: Modulation of neural circuits underlying temporal production by facial expressions of pain
Modulation of neural circuits underlying temporal production by facial expressions of pain Open
According to the Scalar Expectancy Theory, humans are equipped with a biological internal clock, possibly modulated by attention and arousal. Both emotions and pain are arousing and can absorb attentional resources, thus causing distortion…
View article: Neural correlates in intertemporal choice of gains and losses.
Neural correlates in intertemporal choice of gains and losses. Open
Intertemporal choices are decisions involving trade-offs among payoffs available at different points in time. We used event-related functional MRI to investigate the neural
\nmechanisms underlying intertemporal preference for symmetric mon…