Fazel Khan
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View article: Ex-vivo Raman spectroscopy and AI-based classification of soft tissue sarcomas
Ex-vivo Raman spectroscopy and AI-based classification of soft tissue sarcomas Open
Soft tissue sarcomas (STS) are a diverse and rare group of malignant tumors arising from the connective tissues of the body, including fibrous tissue, muscles, fat, nerves, and blood vessels. The heterogeneity and infrequency of these tumo…
View article: Improved Accuracy in Pelvic Tumor Resections Using a Real‐Time Vision‐Guided Surgical System
Improved Accuracy in Pelvic Tumor Resections Using a Real‐Time Vision‐Guided Surgical System Open
Pelvic bone tumor resections remain significantly challenging due to complex three‐dimensional anatomy and limited surgical visualization. While accurate, current navigation systems and patient‐specific instruments present limitations, inc…
View article: Application of Raman Spectroscopy Using a Handheld Probe to Characterize Human White Adipose Tissue
Application of Raman Spectroscopy Using a Handheld Probe to Characterize Human White Adipose Tissue Open
Raman spectroscopy analysis has been used successfully to distinguish normal from neoplastic tissue during surgical resection of tumors. However, microscopic Raman spectroscopy is typically time‐consuming and restricted to examining only a…
View article: A Novel Rat Model to Simulate Positive Margins in the Wound Bed of a Resected Sarcoma
A Novel Rat Model to Simulate Positive Margins in the Wound Bed of a Resected Sarcoma Open
Background: One reason for local recurrence is the presence of positive surgical margins after tumor resection. An animal model accurately representing the microtumor burden will improve our understanding of these surgical margins. Using a…
View article: Pubic Aneurysmal Bone Cyst Following Penile Inversion Vaginoplasty: A Case Report.
Pubic Aneurysmal Bone Cyst Following Penile Inversion Vaginoplasty: A Case Report. Open
Although it is impossible to distinguish coincidence from causation in this case, the patient's recency of PIV and development of a rare ABC in a nearby bone warrants the speculation and discussion provided in this report.
View article: Idiopathic Spontaneous Occurrence of Heterotrophic Occurrence During Pregnancy
Idiopathic Spontaneous Occurrence of Heterotrophic Occurrence During Pregnancy Open
Heterotopic ossification (HO) typically presents in the hip, knee, and elbow joints in the setting of trauma or postsurgical intervention. Less commonly, it may occur secondary to neurologic dysfunction or underlying genetic conditions, bu…
View article: The Management of an Open Biopsy Tract Site Infection and Ulceration in the Setting of Osteosarcoma
The Management of an Open Biopsy Tract Site Infection and Ulceration in the Setting of Osteosarcoma Open
Biopsy site infection in the setting of osteosarcoma is a potentially devastating complication. We present the case of a 16-year-old adolescent girl with a distal femur osteosarcoma who developed an open biopsy site ulceration and infectio…
View article: Glomus Tumor of the Lower Extremity Previously Misdiagnosed as Complex Regional Pain Syndrome in Close Proximity to a Myxofibrosarcoma: A Case Report
Glomus Tumor of the Lower Extremity Previously Misdiagnosed as Complex Regional Pain Syndrome in Close Proximity to a Myxofibrosarcoma: A Case Report Open
Complex regional pain syndrome (CRPS) is a potentially devastating condition that can result in severe psychological and social morbidity. It is a diagnosis of exclusion, and other pathologic entities must be ruled out first. Glomus tumors…
View article: A Novel 3D Light Assisted Drawing (3D-LAD) Method to Aid Intraoperative Reproduction of Osteotomy Lines Surrounding a Bone Tumor During Wide Resection: An Experimental Study
A Novel 3D Light Assisted Drawing (3D-LAD) Method to Aid Intraoperative Reproduction of Osteotomy Lines Surrounding a Bone Tumor During Wide Resection: An Experimental Study Open
In summary, we developed a novel 3D-LAD navigation technology. From the experimental study, we demonstrated that the method can improve the ability of surgeons to accurately draw the preoperative osteotomy lines and perform resection of a …
View article: Systemic Mastocytosis Presenting as Pathologic Intertrochanteric Femur Fracture
Systemic Mastocytosis Presenting as Pathologic Intertrochanteric Femur Fracture Open
Systemic mastocytosis (SM) is pathologically characterized by the proliferation of mast cells with infiltrates in various organs, almost always including bone marrow, leading to defects in bone remodeling. Osteoporosis and subsequent fragi…
View article: Inflammatory Myofibroblastic Tumor 12 Years After Treatment for Synovial Sarcoma: A Case Report
Inflammatory Myofibroblastic Tumor 12 Years After Treatment for Synovial Sarcoma: A Case Report Open
Inflammatory myofibroblastic tumors (IMTs) are mesenchymal neoplasms most seen in the abdominopelvic region, lung, and retroperitoneum; and less commonly seen in virtually any other site. We report a case of two lower limb masses consisten…
View article: Treatment Approach for Knee Osteoarthritis with Ipsilateral Femoral Cartilage Tumor: A Case Series
Treatment Approach for Knee Osteoarthritis with Ipsilateral Femoral Cartilage Tumor: A Case Series Open
Osteoarthritis (OA) is a common pathology affecting the knee joint. Twenty percent of the cartilaginous tumors of bone are in the distal femur. This presents a challenge for treating patients with knee OA who also have ipsilateral distal f…
View article: Classification of Soft Tissue Sarcoma Specimens with Raman Spectroscopy as Smart Sensing Technology
Classification of Soft Tissue Sarcoma Specimens with Raman Spectroscopy as Smart Sensing Technology Open
Intraoperative confirmation of negative resection margins is an essential component of soft tissue sarcoma surgery. Frozen section examination of samples from the resection bed after excision of sarcomas is the gold standard for intraopera…
View article: Hip disarticulation with pedicled total leg fillet flap for recurrent fungating sarcoma
Hip disarticulation with pedicled total leg fillet flap for recurrent fungating sarcoma Open
Soft tissue sarcomas may be treated with limb-sparing procedures in the majority of cases; however, certain cases involving significant tumor spread and fungation may call for amputation. In the thigh, hip disarticulation typically involve…
View article: Management of an Unusual Periprosthetic Giant Cell Tumor of Bone of the Proximal Tibia
Management of an Unusual Periprosthetic Giant Cell Tumor of Bone of the Proximal Tibia Open
Giant cell tumor of bone is a relatively rare type of bone tumor, accounting for approximately 4.9% to 9% of all primary osseous neoplasms.1 Management options include intralesional curettage, or more uncommonly, wide resection. This proce…
View article: Abstract: 9.00 The Safety And Efficacy Of Utilizing Negative Pressure Wound Therapy After Sarcoma Resection
Abstract: 9.00 The Safety And Efficacy Of Utilizing Negative Pressure Wound Therapy After Sarcoma Resection Open
INTRODUCTION: The use of Negative-Pressure Wound Therapy (NPWT) on post-sarcoma resection wounds with uncertain margins is controversial due to the fear that it could promote cancer cell growth. There is no clinical or basic science data t…