Federico Giannuzzi
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View article: Longitudinal changes in choroidal thickness in high myopia: Correlation with maculopathy progression and visual outcomes
Longitudinal changes in choroidal thickness in high myopia: Correlation with maculopathy progression and visual outcomes Open
Purpose To evaluate longitudinal changes in choroidal thickness (CT) in highly myopic eyes and their correlation with myopic maculopathy progression and visual outcomes. Methods Retrospective cohort study on 1228 eyes from 781 highly myopi…
View article: Ophthalmological signs and sensorimotor evaluation in mitochondrial chronic progressive external ophthalmoplegia: a multidisciplinary prospective study
Ophthalmological signs and sensorimotor evaluation in mitochondrial chronic progressive external ophthalmoplegia: a multidisciplinary prospective study Open
A significant number of patients not complaining of double vision in casual seeing state showed manifest or latent/manifest strabismus at FAoD and NAoD. Most strabismic patients had a monocular suppression or alternate diplopia and suppres…
View article: Heavy Versus Standard Silicone Oil Tamponade in Primary Retinal Detachment Surgery: a Systematic Review and Meta-Analysis
Heavy Versus Standard Silicone Oil Tamponade in Primary Retinal Detachment Surgery: a Systematic Review and Meta-Analysis Open
Purpose: To compare the anatomical and functional outcomes of heavy and standard silicone oil (HSO and SSO) in primary rhegmatogenous retinal detachment (RRD), along with post-operative complications. Methods: Meta-analysis conducted in ac…
View article: The human amniotic membrane in vitreoretinal surgery: Applications, outcomes and limitations
The human amniotic membrane in vitreoretinal surgery: Applications, outcomes and limitations Open
The human amniotic membrane (hAM) has gained recognition as a valuable biological adjunct in vitreoretinal surgery, with its applications rapidly expanding since its initial use for macular holes (MHs). We examine the development and prese…
View article: The Role of Multidisciplinary Ocular and Periocular Cancers Meetings in Uveal Melanoma Management: A 2-Year Analysis
The Role of Multidisciplinary Ocular and Periocular Cancers Meetings in Uveal Melanoma Management: A 2-Year Analysis Open
Purpose: The objective of this study was to evaluate the implementation of a Multidisciplinary Tumor Board (MDTB) strategy in the treatment of patients with uveal melanoma. Methods: A retrospective analysis was conducted on the implementat…
View article: Testing the Reliability of ChatGPT Assistance for Surgical Choices in Challenging Glaucoma Cases
Testing the Reliability of ChatGPT Assistance for Surgical Choices in Challenging Glaucoma Cases Open
Background: This study’s aim is to assess ChatGPT’s capability to analyze detailed case descriptions in glaucomatous patients and suggest the best possible surgical treatment. Methods: We conducted a retrospective analysis of 60 medical re…
View article: The applications of viscoelastic agents in vitreoretinal surgery
The applications of viscoelastic agents in vitreoretinal surgery Open
View article: Intravitreal Injections of Cord Blood Platelet-Rich Plasma in Dry Age-Related Macular Degeneration: Regenerative Therapy
Intravitreal Injections of Cord Blood Platelet-Rich Plasma in Dry Age-Related Macular Degeneration: Regenerative Therapy Open
View article: Radiomic Feature Extraction from OCT Angiography of Idiopathic Epiretinal Membranes and Correlation with Visual Acuity: A Pilot Study
Radiomic Feature Extraction from OCT Angiography of Idiopathic Epiretinal Membranes and Correlation with Visual Acuity: A Pilot Study Open
View article: Cord blood platelet-rich plasma: proteomics analysis for ophthalmic applications
Cord blood platelet-rich plasma: proteomics analysis for ophthalmic applications Open
Our objective is to determine the protein and complements constituents of Cord blood Platelet-rich plasma (CB-PRP), based on the hypothesis that it contains beneficial components capable of arresting or potentially decelerating the advance…
View article: New combined treatments, surgery and high-dose-rate interventional radiotherapy (brachytherapy), in advanced ocular surface and eyelid cancers
New combined treatments, surgery and high-dose-rate interventional radiotherapy (brachytherapy), in advanced ocular surface and eyelid cancers Open
View article: Testing the power of Google DeepMind: Gemini versus ChatGPT 4 facing a European ophthalmology examination
Testing the power of Google DeepMind: Gemini versus ChatGPT 4 facing a European ophthalmology examination Open
The aim of this study was to compare the performances of Google Gemini and ChatGPT-4, facing a triple simulation of the European Board of Ophthalmologists (EBO) multiple choices exam. Observational study. The EBO multiple choice examinatio…
View article: State of the art, advantages and drawbacks of XEN 63 gel stent in glaucoma surgery
State of the art, advantages and drawbacks of XEN 63 gel stent in glaucoma surgery Open
The XEN gel stent (Allergan) is a minimally-invasive, subconjunctival bleb-forming device designed for glaucoma surgery. Originally available in three sizes (45, 63 and 140 μm), it consists of a flexible, permanent collagen implant that is…
View article: Heavy silicone oil tamponade in retinal detachment surgery: A systematic review and single-arm meta-analysis on Densiron 68 and Oxane HD
Heavy silicone oil tamponade in retinal detachment surgery: A systematic review and single-arm meta-analysis on Densiron 68 and Oxane HD Open
Heavy silicone oils (HSOs) have been introduced in rhegmatogenous retinal detachment (RRD) surgery to support inferior/posterior breaks and proliferative vitreoretinopathy (PVR). This meta-analysis assessed the results and adverse effects …
View article: Optical Coherence Tomography Advanced Parameters in Patients With Multiple Sclerosis: Ophthalmological and Neurological Assessments
Optical Coherence Tomography Advanced Parameters in Patients With Multiple Sclerosis: Ophthalmological and Neurological Assessments Open
Several OCT and OCTA-optic nerve parameters could be useful prognostic biomarkers for the MS disease course in clinical practice. However, it is necessary to do additional research with larger sample sizes in order to validate these findin…
View article: Breast cancer orbital metastases: Clinical, histopathological features and disease related survival in a retrospective case series
Breast cancer orbital metastases: Clinical, histopathological features and disease related survival in a retrospective case series Open
To analyze the clinical, radiological and histopathological features, and long-term follow-up of patients with orbital metastases originating from a primary breast carcinoma. Main outcomes were: demographic characteristics of the populatio…
View article: Large language models as assistance for glaucoma surgical cases: a ChatGPT vs. Google Gemini comparison
Large language models as assistance for glaucoma surgical cases: a ChatGPT vs. Google Gemini comparison Open
View article: Exclusive Ru-106 brachytherapy for the management of a recurrent corneo: Conjunctival squamous cell carcinoma
Exclusive Ru-106 brachytherapy for the management of a recurrent corneo: Conjunctival squamous cell carcinoma Open
Brachytherapy treatment showed optimal management of both corneal and conjunctival involvement, with a free-of-disease follow-up of 24-months. This result suggests that, in specific conditions, Ru-106 brachytherapy could be an effective op…
View article: Ocular Involvement in Systemic Sclerosis: Updated Review and New Insights on Microvascular Impairment
Ocular Involvement in Systemic Sclerosis: Updated Review and New Insights on Microvascular Impairment Open
Systemic sclerosis (SSc) is a chronic multisystemic disease characterized by immunological activation, diffuse vasculopathy, and generalized fibrosis exhibiting a variety of symptoms. A recognized precursor of SSc is Raynaud's phenomenon, …
View article: Ranibizumab Port Delivery System in Neovascular Age-Related Macular Degeneration: Where Do We Stand? Overview of Pharmacokinetics, Clinical Results, and Future Directions
Ranibizumab Port Delivery System in Neovascular Age-Related Macular Degeneration: Where Do We Stand? Overview of Pharmacokinetics, Clinical Results, and Future Directions Open
The ranibizumab (RBZ) port delivery system (PDS) is a device designed to continuously deliver RBZ in the vitreous chamber for the treatment of neovascular age-related macular degeneration (nAMD). It is implanted during a surgical procedure…
View article: Safety Results for Geographic Atrophy Associated with Age-Related Macular Degeneration Using Subretinal Cord Blood Platelet-Rich Plasma
Safety Results for Geographic Atrophy Associated with Age-Related Macular Degeneration Using Subretinal Cord Blood Platelet-Rich Plasma Open
Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
View article: Base-Excision Repair Mutational Signature in Two Sebaceous Carcinomas of the Eyelid
Base-Excision Repair Mutational Signature in Two Sebaceous Carcinomas of the Eyelid Open
Personalized medicine aims to develop tailored treatments for individual patients based on specific mutations present in the affected organ. This approach has proven paramount in cancer treatment, as each tumor carries distinct driver muta…
View article: Ophthalmological signs and sensorimotor evaluation in mitochondrial diseases: a multidisciplinary prospective study
Ophthalmological signs and sensorimotor evaluation in mitochondrial diseases: a multidisciplinary prospective study Open
Background. Primary mitochondrial myopathies (PMM) are disorders that involve defects in oxidative phosphorylation (OXPHOS) and impair mainly, but not exclusively, skeletal muscles. Progressive external ophthalmoplegia (PEO), eyelid ptosis…
View article: Orbital cellulitis and massive chemosis as first sign of a cilio-choroidal malignant melanoma without extraocular extension: A case report
Orbital cellulitis and massive chemosis as first sign of a cilio-choroidal malignant melanoma without extraocular extension: A case report Open
Purpose: To describe a case of cilio-choroidal melanoma presenting as aseptic orbital cellulitis with massive conjunctival chemosis. Methods: Case report. Results: A 51-year-old man with a left retro-iris pigmented lesion had acute lid ede…
View article: Ophthalmic Manifestations in Fabry Disease: Updated Review
Ophthalmic Manifestations in Fabry Disease: Updated Review Open
Fabry disease (FD) is an X-linked lysosomal storage disorder, causing Gb-3 (globotriaosylceramide) buildup in cellular lysosomes throughout the body, in particular in blood vessel walls, neuronal cells, and smooth muscle. The gradual accum…
View article: 3D Da Vinci robotic surgery: is it a risk to the surgeon’s eye health?
3D Da Vinci robotic surgery: is it a risk to the surgeon’s eye health? Open
View article: Early post-operative anterior segment parameters modifications induced by PreserFlo MicroShunt in primary open-angle glaucoma
Early post-operative anterior segment parameters modifications induced by PreserFlo MicroShunt in primary open-angle glaucoma Open
Purpose The aim this study is to determine anterior chamber parameters variations induced by PreserFlo MicroShunt implantation, in the early post-operative days. Methods This is a prospective observational study on 48 eyes undergoing Prese…
View article: Spontaneous ciliary body detachment in a Marfan patient: A case of personalized management
Spontaneous ciliary body detachment in a Marfan patient: A case of personalized management Open
View article: Sutureless scleral fixation Carlevale IOL: a review on the novel designed lens
Sutureless scleral fixation Carlevale IOL: a review on the novel designed lens Open
View article: Supportive treatment to chemotherapy with MMC, in patients with ocular surface squamous neoplasia or conjunctival melanocytic tumor
Supportive treatment to chemotherapy with MMC, in patients with ocular surface squamous neoplasia or conjunctival melanocytic tumor Open