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View article: Real-world survival and prognostic factors in WHO 2021 classified gliomas treated with chemo-radiotherapy
Real-world survival and prognostic factors in WHO 2021 classified gliomas treated with chemo-radiotherapy Open
View article: EP12.04 REAL-WORLD SURVIVAL OUTCOMES AFTER (CHEMO)RADIOTHERAPY FOR WHO 2021-CLASSIFIED GLIOMAS: A MULTICENTER ANALYSIS OF CLINICAL, TREATMENT-RELATED, DOSIMETRIC, AND HEMATOLOGIC PROGNOSTIC FACTORS
EP12.04 REAL-WORLD SURVIVAL OUTCOMES AFTER (CHEMO)RADIOTHERAPY FOR WHO 2021-CLASSIFIED GLIOMAS: A MULTICENTER ANALYSIS OF CLINICAL, TREATMENT-RELATED, DOSIMETRIC, AND HEMATOLOGIC PROGNOSTIC FACTORS Open
BACKGROUND The 2021 WHO classification of gliomas introduced molecular profiling into the diagnostic criteria, reshaping prognosis and therapeutic strategies. However, most existing outcomes data are based on previous classifications, crea…
View article: Penalized-Survival Nomogram Predicts 5-Year Metastasis-Free Survival After Salvage Radiotherapy for Postprostatectomy Patients: A Multicenter Study
Penalized-Survival Nomogram Predicts 5-Year Metastasis-Free Survival After Salvage Radiotherapy for Postprostatectomy Patients: A Multicenter Study Open
This externally validated nomogram provides a practical tool for predicting 5-year DMFS in patients undergoing SRT. It enables personalized risk assessment, guiding intensified surveillance and treatment for high-risk patients.
View article: Real-World Survival Outcomes After (Chemo)radiotherapy for WHO 2021-Classified Gliomas: A Multicenter Analysis of Clinical, Treatment-Related, Dosimetric, and Hematologic Prognostic Factors
Real-World Survival Outcomes After (Chemo)radiotherapy for WHO 2021-Classified Gliomas: A Multicenter Analysis of Clinical, Treatment-Related, Dosimetric, and Hematologic Prognostic Factors Open
The 2021 WHO glioma classification integrates molecular profiling, but outcome data for these patients are limited. We retrospectively analyzed 179 patients (median age 53) with WHO 2021-classified gliomas (grade 2: n = 45, grade 3: n = 51…
View article: CT-Based Radiomics Enhance Respiratory Function Analysis for Lung SBRT
CT-Based Radiomics Enhance Respiratory Function Analysis for Lung SBRT Open
Introduction: Radiomics is the extraction of non-invasive and reproducible quantitative imaging features, which may yield mineable information for clinical practice implementation. Quantification of lung function through radiomics could pl…
View article: Interventional stereotactic radiotherapy (brachytherapy) for unresected brain metastases: Systematic review of outcome and toxicity
Interventional stereotactic radiotherapy (brachytherapy) for unresected brain metastases: Systematic review of outcome and toxicity Open
View article: Harnessing Baseline Radiomic Features in Early-Stage NSCLC: What Role in Clinical Outcome Modeling for SBRT Candidates?
Harnessing Baseline Radiomic Features in Early-Stage NSCLC: What Role in Clinical Outcome Modeling for SBRT Candidates? Open
Aim: An Early-Stage Non-Small Cell Lung Cancer (ES-NSCLC) patient candidate for stereotactic body radiotherapy (SBRT) may start their treatment without a histopathological assessment, due to relevant comorbidities. The aim of this study is…
View article: Exploratory analysis of the professional quality of life in an Italian radiotherapy department: The role of empathy and alexithymia
Exploratory analysis of the professional quality of life in an Italian radiotherapy department: The role of empathy and alexithymia Open
Purpose: Professional quality of life (QoL) is crucial for healthcare workers as it affects performance at work and interaction with patients, but little is known about stressors influencing radiation oncology professionals. The present st…
View article: Understanding the role of nerves in head and neck cancers - a review
Understanding the role of nerves in head and neck cancers - a review Open
Worldwide, head and neck cancers (HNCs) account for approximately 900,000 cases and 500,000 deaths annually, with their incidence continuing to rise. Carcinogenesis is a complex, multidimensional molecular process leading to cancer develop…
View article: Survival outcomes and toxicity profile after CT-guided HDR brachytherapy (interventional radiotherapy) for liver oligometastases in breast cancer patients: The BRALIBREST real world multicenter study
Survival outcomes and toxicity profile after CT-guided HDR brachytherapy (interventional radiotherapy) for liver oligometastases in breast cancer patients: The BRALIBREST real world multicenter study Open
View article: The emerging role of Artificial Intelligence in proton therapy: A review
The emerging role of Artificial Intelligence in proton therapy: A review Open
View article: Half body irradiation (HBI) for bone metastases in the modern radiotherapy technique era – A systematic review
Half body irradiation (HBI) for bone metastases in the modern radiotherapy technique era – A systematic review Open
Bone metastases (BMs) are the most common cause of cancer-related pain and radiation therapy plays a key role in treating pain caused by it. The half-body irradiation (HBI) is a modality that can be used to treat patients with multiple pai…
View article: Image-Guided Stereotactic Body Radiotherapy on Detectable Prostate Bed Recurrence after Prostatectomy in RT-Naïve Patients
Image-Guided Stereotactic Body Radiotherapy on Detectable Prostate Bed Recurrence after Prostatectomy in RT-Naïve Patients Open
Purpose or Objective—The aim of the study is to evaluate the efficacy and safety of SBRT on detectable prostate bed recurrence in RT-naïve prostate cancer patients. Materials and methods: Eighty-six patients who underwent SBRT for macrosco…
View article: Muscle-invasive bladder cancer in elderly and frail people: Is hypofractionated radiotherapy a feasible approach when no other local options are available?
Muscle-invasive bladder cancer in elderly and frail people: Is hypofractionated radiotherapy a feasible approach when no other local options are available? Open
Aim: The study aims to report the feasibility and safety of palliative hypofractionated radiotherapy targeting macroscopic bladder tumors in a monocentric cohort of frail and elderly bladder cancer patients not eligible for curative treatm…
View article: Post-operative KEloids iRradiation (POKER): does the surgery/high-dose interventional radiotherapy association make a winning hand?
Post-operative KEloids iRradiation (POKER): does the surgery/high-dose interventional radiotherapy association make a winning hand? Open
Purpose To report the results involving post-operative interventional radiotherapy (POIRT) in a homogenous cohort of patients affected by keloid and treated at a single institution with the same fractionation schedule. Patients and Methods…
View article: Multi-omics integrative modelling for stereotactic body radiotherapy in early-stage non-small cell lung cancer: clinical trial protocol of the MONDRIAN study
Multi-omics integrative modelling for stereotactic body radiotherapy in early-stage non-small cell lung cancer: clinical trial protocol of the MONDRIAN study Open
Background Currently, main treatment strategies for early-stage non-small cell lung cancer (ES-NSCLC) disease are surgery or stereotactic body radiation therapy (SBRT), with successful local control rates for both approaches. However, regi…
View article: More than Five Decades of Proton Therapy: A Bibliometric Overview of the Scientific Literature
More than Five Decades of Proton Therapy: A Bibliometric Overview of the Scientific Literature Open
Background: The therapeutic potential of proton therapy (PT) was first recognized in 1946 by Robert Wilson, and nowadays, over 100 proton centers are in operation worldwide, and more than 60 are under construction or planned. Bibliometric …
View article: Investigating Nutritional and Inflammatory Status as Predictive Biomarkers in Oligoreccurent Prostate Cancer—A RADIOSA Trial Preliminary Analysis
Investigating Nutritional and Inflammatory Status as Predictive Biomarkers in Oligoreccurent Prostate Cancer—A RADIOSA Trial Preliminary Analysis Open
(1) Background: In the RADIOSA phase II randomized clinical trial (NCT03940235), the biology task entails the identification of predictive and prognostic biomarkers in the context of oligorecurrent, castration-sensitive prostate cancer in …
View article: Automatic Segmentation with Deep Learning in Radiotherapy
Automatic Segmentation with Deep Learning in Radiotherapy Open
This review provides a formal overview of current automatic segmentation studies that use deep learning in radiotherapy. It covers 807 published papers and includes multiple cancer sites, image types (CT/MRI/PET), and segmentation methods.…
View article: Cyberknife Radiosurgery for Prostate Cancer after Abdominoperineal Resection (CYRANO): The Combined Computer Tomography and Electromagnetic Navigation Guided Transperineal Fiducial Markers Implantation Technique
Cyberknife Radiosurgery for Prostate Cancer after Abdominoperineal Resection (CYRANO): The Combined Computer Tomography and Electromagnetic Navigation Guided Transperineal Fiducial Markers Implantation Technique Open
In this technical development report, we present the strategic placement of fiducial markers within the prostate under the guidance of computed tomography (CT) and electromagnetic navigation (EMN) for the delivery of ultra-hypofractionated…
View article: A Bibliometric Analysis of the Oligometastatic State over the Last Two Decades: A Shifting Paradigm for Oncology? An AIRO Oligometastatic Study Group
A Bibliometric Analysis of the Oligometastatic State over the Last Two Decades: A Shifting Paradigm for Oncology? An AIRO Oligometastatic Study Group Open
The term “oligometastasis” represents a relatively novel idea, which denotes a condition characterized by cancer dissemination with a limited number of lesions (usually fewer than five). The aim of the present study is to report a bibliome…
View article: Quo vadis Radiomics? Bibliometric analysis of 10-year Radiomics journey
Quo vadis Radiomics? Bibliometric analysis of 10-year Radiomics journey Open
View article: Blood- and Imaging-Derived Biomarkers for Oncological Outcome Modelling in Oropharyngeal Cancer: Exploring the Low-Hanging Fruit
Blood- and Imaging-Derived Biomarkers for Oncological Outcome Modelling in Oropharyngeal Cancer: Exploring the Low-Hanging Fruit Open
Aims: To assess whether CT-based radiomics and blood-derived biomarkers could improve the prediction of overall survival (OS) and locoregional progression-free survival (LRPFS) in patients with oropharyngeal cancer (OPC) treated with curat…
View article: What is the best time for postoperative radiation therapy in pN1 prostate cancer?
What is the best time for postoperative radiation therapy in pN1 prostate cancer? Open
We retrospectively compared long-term biochemical recurrence rates (BCR) in pN1 PCa patients that underwent adjuvant radiotherapy (aRT) vs. no aRT/early salvage (esRT) after robot-assisted radical prostatectomy and extended pelvic lymphade…
View article: Variation in Body Mass and Skeletal Muscle Indices in Head and Neck Cancer Patients Undergoing (Chemo)Radiotherapy and Nutritional Intervention
Variation in Body Mass and Skeletal Muscle Indices in Head and Neck Cancer Patients Undergoing (Chemo)Radiotherapy and Nutritional Intervention Open
The aim of this study was to analyze variation in body mass index (BMI) and skeletal muscle index (SMI) in head and neck squamous cell carcinoma (HNSCC) patients who underwent exclusive radiotherapy (RT) or concurrent chemo-radiotherapy (R…
View article: Virtual and Augmented Reality as a Novel Opportunity to Unleash the Power of Radiotherapy in the Digital Era: A Scoping Review
Virtual and Augmented Reality as a Novel Opportunity to Unleash the Power of Radiotherapy in the Digital Era: A Scoping Review Open
Although radiation therapy (RT) provides several therapeutic advantages in terms of cancer control and quality of life, it continues to be a poorly understood field by most students and health workers. Theoretical lessons are not sufficien…
View article: Correlation of [18F] FDG-PET/CT with dosimetry data: recurrence pattern after radiotherapy for head and neck carcinoma
Correlation of [18F] FDG-PET/CT with dosimetry data: recurrence pattern after radiotherapy for head and neck carcinoma Open
View article: Impact of covid‐19 pandemic on residency programs in italy: A cross-sectional study
Impact of covid‐19 pandemic on residency programs in italy: A cross-sectional study Open
The current COVID-19 pandemic has imposed a remodulation of hospital activities. This has resulted in an increase in the workload for those sectors directly involved in the emergency (infectious diseases, hygiene and preventive medicine, i…
View article: Correlation of [18F] FDG-PET/CT with dosimetry data: recurrence pattern after radiotherapy for head and neck carcinoma
Correlation of [18F] FDG-PET/CT with dosimetry data: recurrence pattern after radiotherapy for head and neck carcinoma Open
ObjectiveTo analyze the pattern of failure in relation to pre-treatment [18F] FDG-PET/CT uptake in head and neck squamous cell carcinoma (HNSCC) patients treated with definitive radio-chemotherapy (RT-CHT).Methods and MaterialsF…
View article: Radiotherapy in COVID-19 patient affected by multiple myeloma: a case report
Radiotherapy in COVID-19 patient affected by multiple myeloma: a case report Open
In COVID-19 pandemic, cancer patients may be vulnerable for their immunological status and need of immunosuppressive anti-neoplastic treatments. Choosing the best treatment option in COVID-19 positive cancer patients is still a challenging…