Feidi Wang
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View article: Indole-3-acetic acid exerts protective effects on sleep deprivation-induced cognitive impairment
Indole-3-acetic acid exerts protective effects on sleep deprivation-induced cognitive impairment Open
The gut microbiota and its metabolites have increasingly been recognized as crucial factors contributing to the cognitive deficits induced by sleep deprivation (SD), a condition characterized by diminished hippocampal neurogenesis. Neverth…
View article: Microencapsulation alters pyraclostrobin degradation and reshapes soil microbial communities compared to conventional formulations
Microencapsulation alters pyraclostrobin degradation and reshapes soil microbial communities compared to conventional formulations Open
These findings offer critical insights into the soil ecological risks of microencapsulated pesticides from the perspective of formulation-degradation behavior-microbial interactions, providing a critical theoretical foundation for precisel…
View article: The thalamic reticular nucleus orchestrates social memory
The thalamic reticular nucleus orchestrates social memory Open
Social memory has been developed in humans and other animals to recognize familiar conspecifics and is essential for their survival and reproduction. Here, we demonstrated that parvalbumin-positive neurons in the sensory thalamic reticular…
View article: Prostaglandin Metabolome Profiles in Zebrafish (Danio rerio) Exposed to Acetochlor and Butachlor
Prostaglandin Metabolome Profiles in Zebrafish (Danio rerio) Exposed to Acetochlor and Butachlor Open
Prostaglandins (PGs) are critically important signaling molecules that play key roles in normal and pathophysiological processes. Many endocrine-disrupting chemicals have been found to suppress PG synthesis; however, studies about the effe…
View article: Dysregulation of prefrontal parvalbumin interneurons leads to adult aggression induced by social isolation stress during adolescence
Dysregulation of prefrontal parvalbumin interneurons leads to adult aggression induced by social isolation stress during adolescence Open
Social isolation during the juvenile stage results in structural and functional impairment of the brain and deviant adult aggression. However, the specific subregions and cell types that underpin this deviant behavior are still largely unk…
View article: Acute and Chronic Toxicity of Prothioconazole and its Metabolite Prothioconazole-Desthio To Daphnia Magna
Acute and Chronic Toxicity of Prothioconazole and its Metabolite Prothioconazole-Desthio To Daphnia Magna Open
Prothioconazole (PTC) is a broad-spectrum triazole fungicide. Current research has mainly focused on its efficacy and residues, with few studies on its toxicological effects. This study assessed the effects of PTC, and its metabolite proth…
View article: Integration of metabolomics and transcriptomics reveals short-chain chlorinated paraffin-induced hepatotoxicity in male Sprague-Dawley rat
Integration of metabolomics and transcriptomics reveals short-chain chlorinated paraffin-induced hepatotoxicity in male Sprague-Dawley rat Open
Results of this work strongly support the conclusion that low-dose exposure to SCCPs can result in adverse outcomes in the rat model. Significant SCCP-induced inhibition of energy metabolism occurs at environmentally relevant dosages, whic…
View article: MYC overexpression with its prognostic and clinicopathological significance in breast cancer
MYC overexpression with its prognostic and clinicopathological significance in breast cancer Open
Our results showed that MYC overexpression was associated with worse prognosis and high risk of breast cancer, especially in patients with negative hormone receptors, which highlighted the potential of MYC as a significant prognostic bioma…
View article: Clinicopathological and prognostic significance of c-Met overexpression in breast cancer
Clinicopathological and prognostic significance of c-Met overexpression in breast cancer Open
Our results showed that c-Met overexpression was connected with poor survival rates and malignant activities of cancer, including proliferation, migration and invasion, which highlighted the potential of c-Met as significant candidate biom…
View article: Prognostic significance of tumor-associated macrophages in breast cancer: a meta-analysis of the literature
Prognostic significance of tumor-associated macrophages in breast cancer: a meta-analysis of the literature Open
High density of TAMs was associated with poor survival rates of breast cancer. TAMs in stroma are associated with worse outcome than that in nest and using CD68 as a biomarker for TAMs to evaluate the risk is better than CD163 or CD206 alo…