Feifan Xiao
YOU?
Author Swipe
View article: The Discovery of MVT-like Ga-Enriched Sphalerite from the Zhaojinci Area in the South Hunan District (South China)
The Discovery of MVT-like Ga-Enriched Sphalerite from the Zhaojinci Area in the South Hunan District (South China) Open
Gallium (Ga) enrichment in sphalerite has been widely recognized; however, its enrichment mechanisms remain insufficiently understood. The South Hunan district, located at the intersection of the Nanling Region and the Qin-Hang Metallogeni…
View article: Brain development in newborns and infants after ECMO
Brain development in newborns and infants after ECMO Open
Background Extracorporeal membrane oxygenation (ECMO) not only significantly improves survival rates in severely ill neonates but also is associated with long-term neurodevelopmental issues. To systematically review the available literatur…
View article: Incidence of Neonatal Seizures in China Based on Electroencephalogram Monitoring in Neonatal Neurocritical Care Units
Incidence of Neonatal Seizures in China Based on Electroencephalogram Monitoring in Neonatal Neurocritical Care Units Open
Importance Neonatal seizures pose a significant challenge in critical care, and continuous video electroencephalography (cEEG) monitoring holds promise for early detection of seizures. However, large-scale data on the incidence of neonatal…
View article: Fourteen cases of cerebral creatine deficiency syndrome in children: a cohort study in China
Fourteen cases of cerebral creatine deficiency syndrome in children: a cohort study in China Open
The prevalence of CCDS is ~0.39% in Chinese children with developmental delay. A low-protein diet, Cr and, ornithine were useful for patients with GAMT deficiency. Male patients with SLC6A8 deficiency showed only limited improvement on com…
View article: Comparison of Genetic Profiles of Neonates in Intensive Care Units Conceived With or Without Assisted Reproductive Technology
Comparison of Genetic Profiles of Neonates in Intensive Care Units Conceived With or Without Assisted Reproductive Technology Open
Importance A growing number of children are conceived with assisted reproductive technology (ART). However, there is a lack of studies systematically analyzing the genetic landscape of live-born children conceived through ART who need inte…
View article: [Clinical practice of whole-genome sequencing in the rapid diagnosis of critically ill neonates].
[Clinical practice of whole-genome sequencing in the rapid diagnosis of critically ill neonates]. Open
WGS technique can provide a timely and effective diagnosis for critically ill neonates suspected of genetic diseases and provide genetic evidence for clinical treatment of critically ill cases.
View article: Clinical features of infants with SARS-CoV-2 infection: a systematic review and meta-analysis
Clinical features of infants with SARS-CoV-2 infection: a systematic review and meta-analysis Open
This meta-analysis found that 20% of infants with SARS-CoV-2 infections were asymptomatic, while most infants with COVID-19 presented with mild symptoms.
View article: Additional file 4 of Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians
Additional file 4 of Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians Open
Additional file 4. Designed capture regions of CES and WES on CFTR gene.
View article: Additional file 1 of Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians
Additional file 1 of Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians Open
Additional file 1. Manually curated CFTR variants’ pathogenicity.
View article: Diagnostic utility of rapid sequencing in critically ill infants: a systematic review and meta-analysis
Diagnostic utility of rapid sequencing in critically ill infants: a systematic review and meta-analysis Open
Genetic disorders are a major cause of death in critically ill infants. Several studies have assessed the diagnostic yield of rapid genomic sequencing in critically ill infants. This meta-analysis aimed to summarize the diagnostic utility …
View article: Additional file 3 of Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians
Additional file 3 of Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians Open
Additional file 3. Collected variants list of Caucasian-specific CF screening panels.
View article: Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians
Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians Open
Background Cystic fibrosis (CF) is a common, life-threatening genetic disease in Caucasians but rarely reported in Chinese population. The prevalence and population-specific genetic spectrum of CF in China needs to be systematically estima…
View article: Neonatal Metabolic Acidosis in the Neonatal Intensive Care Unit: What Are the Genetic Causes?
Neonatal Metabolic Acidosis in the Neonatal Intensive Care Unit: What Are the Genetic Causes? Open
Neonatal metabolic acidosis (NMA) is a common problem, particularly in critically ill patients in neonatal intensive care units (NICUs). Complex etiologies and atypical clinical signs make diagnosis difficult; thus, it is crucial to invest…
View article: Overcoming the pitfalls of NGS-based molecular diagnosis of Shwachman-Diamond syndrome
Overcoming the pitfalls of NGS-based molecular diagnosis of Shwachman-Diamond syndrome Open
Purpose Shwachman-Diamond syndrome (SDS) is predominately caused by biallelic mutations in the SBDS gene and is characterized by exocrine pancreatic insufficiency, skeletal abnormalities and pancytopenia. Gene conversion between SBDS and i…
View article: High-Frequency Exon Deletion of DNA Cross-Link Repair 1C Accounting for Severe Combined Immunodeficiency May Be Missed by Whole-Exome Sequencing
High-Frequency Exon Deletion of DNA Cross-Link Repair 1C Accounting for Severe Combined Immunodeficiency May Be Missed by Whole-Exome Sequencing Open
Next-generation sequencing (NGS) has been used to detect severe combined immunodeficiency (SCID) in patients, and some patients with DNA cross-link repair 1C ( DCLRE1C ) variants have been identified. Moreover, some compound variants, such…
View article: Protocol of the China Neonatal Genomes Project: an observational study about genetic testing on 100,000 neonates
Protocol of the China Neonatal Genomes Project: an observational study about genetic testing on 100,000 neonates Open
Background: Genetic diseases are caused by gene variants or chromosomal anomalies. The early diagnosis of genetic diseases is vital for patients. Next-generation sequencing has been widely used in the diagnosis of genetic diseases in recen…
View article: Combining Metagenomic Sequencing With Whole Exome Sequencing to Optimize Clinical Strategies in Neonates With a Suspected Central Nervous System Infection
Combining Metagenomic Sequencing With Whole Exome Sequencing to Optimize Clinical Strategies in Neonates With a Suspected Central Nervous System Infection Open
Objectives Central nervous system (CNS) infection has a high incidence and mortality in neonates, but conventional tests are time-consuming and have a low sensitivity. Some rare genetic diseases may have some similar clinical manifestation…
View article: Overdosage of HNF1B Gene Associated With Annular Pancreas Detected in Neonate Patients With 17q12 Duplication
Overdosage of HNF1B Gene Associated With Annular Pancreas Detected in Neonate Patients With 17q12 Duplication Open
The annular pancreas (AP) is a congenital anomaly of the pancreas that can cause acute abdominal pain and vomiting after birth. However, the genetic cause of AP is still unknown, and no study has reported AP in patients with 17q12 duplicat…
View article: Amplitude of low-frequency fluctuation may be an early predictor of delayed motor development due to neonatal hyperbilirubinemia: a fMRI study
Amplitude of low-frequency fluctuation may be an early predictor of delayed motor development due to neonatal hyperbilirubinemia: a fMRI study Open
The ALFF value may be able to serve as an early imaging biomarker and has a greater sensitivity than TSB or BAEP results in predicting long-term motor development (18 m) in HB.
View article: Time Distributions of Common Respiratory Pathogens Under the Spread of SARS-CoV-2 Among Children in Xiamen, China
Time Distributions of Common Respiratory Pathogens Under the Spread of SARS-CoV-2 Among Children in Xiamen, China Open
Objectives: The aim of this study was to observe the effect of COVID-19 prevention and control measures on the transmission of common respiratory viruses in a pediatric population. Methods: This was a retrospective observational study. The…
View article: Supplementary Material for: Differences in the Clinical Manifestations and Mortality of Systemic Lupus Erythematosus Onset in Children and Adults: A Systematic Review and Meta-Analysis
Supplementary Material for: Differences in the Clinical Manifestations and Mortality of Systemic Lupus Erythematosus Onset in Children and Adults: A Systematic Review and Meta-Analysis Open
Introduction: The aim of this study was to assess the differences between childhood-onset and adult-onset systemic lupus erythematosus (cSLE and aSLE) for clinical manifestations and mortality using a meta-analytic approach. Methods: The P…
View article: Children with SARS-CoV-2 infection during an epidemic in China (outside of Hubei province)
Children with SARS-CoV-2 infection during an epidemic in China (outside of Hubei province) Open
Family clustering transmission is currently the main model of transmission in children. Considering the mild symptoms in infected children, the possibility that children may be a source of the transmission should not be ignored.
View article: [Clinical features and SLC6A8 gene mutations of cerebral creatine deficiency syndrome I: an analysis of two families].
[Clinical features and SLC6A8 gene mutations of cerebral creatine deficiency syndrome I: an analysis of two families]. Open
This article reports the clinical and genetic features of two cases of cerebral creatine deficiency syndrome I (CCDSI) caused by SLC6A8 gene mutations. Both children were boys. Boy 1 (aged 2 years and 10 months) and Boy 2 (aged 8 years and…
View article: Neonatal Early-Onset Infection With SARS-CoV-2 in 33 Neonates Born to Mothers With COVID-19 in Wuhan, China
Neonatal Early-Onset Infection With SARS-CoV-2 in 33 Neonates Born to Mothers With COVID-19 in Wuhan, China Open
This cohort study examines medical records of 33 neonates born to women with COVID-19 to provide information on maternal-child transmission and infant outcomes.