Explanipedia

Enhanced recovery and survival after elective surgery for colorectal cancer - propensity score weighting analysis of 2,865 prospective patients Open

Marco Catarci, Stefano Guadagni, Marco Scatizzi, Raffaele De Luca, Paolo Delrio , et al. · 2025

High adherence to ERP was associated to a significant impact on long-term overall survival, supporting the efforts towards proper ERP implementation after CCS.

Length of stay after colorectal surgery in Italy: the gap between “fit for” and “actual” discharge in a prospective cohort of 4529 cases Open

Lorenzo Pandolfini, D Conti, Piercarlo Ballo, S Rollo, Alessandro Falsetto , et al. · 2025

Among other factors, the gap between FFD and AD had an independent impact on LOS. The most frequent reasons for this gap were "not willing to return home" and "social constraint", while the "need for postoperative rehabilitation" had the g…

Bowel preparation for elective colorectal resection: multi-treatment machine learning analysis on 6241 cases from a prospective Italian cohort Open

Marco Catarci, Stefano Guadagni, Francesco Masedu, Giacomo Ruffo, Massimo Viola , et al. · 2024

Abdominal drainage after elective colorectal surgery: propensity score-matched retrospective analysis of an Italian cohort Open

Stefano Guadagni, Marco Catarci, Francesco Masedu, Mohammad Ehsanul Karim, Marco Clementi , et al. · 2024

Background In Italy, surgeons continue to drain the abdominal cavity in more than 50 per cent of patients after colorectal resection. The aim of this study was to evaluate the impact of abdominal drain placement on early adverse events in …

Current status of liver surgery for non-colorectal non-neuroendocrine liver metastases: the NON.LI.MET. Italian Society for Endoscopic Surgery and New Technologies (SICE) and Association of Italian Surgeons in Europe (ACIE) collaborative international survey Open

Annarita Libia, Mauro Podda, Marcello Di Martino, Francesco Pata, Gianluca Pellino , et al. · 2023

PB1472 One-Week versus Extended Antithrombotic Prophylaxis after Laparoscopic Surgery for Colorectal Cancer: An Individual Patient Meta-Analysis Open

Cecilia Becattini, Fabio Rondelli, Ugo Pace, Felice Pirozzi, Giuseppe Camporese , et al. · 2023

stable over recent years.Stratification for subgroups will enable orthopedic surgeons to better inform their patients.

Robotic Ventral Rectopexy for Rectal Prolapse Open

Antonio Sciuto, Luca Montesarchio, Alfredo Pede, Felice Pirozzi · 2023

Rectal prolapse or procidentia is a debilitating condition that typically presents in parous older women but can occur in men and women of all ages. Surgery is the mainstay for the treatment of rectal prolapse and can be performed through …

High adherence to enhanced recovery pathway independently reduces major morbidity and mortality rates after colorectal surgery: a reappraisal of the iCral2 and iCral3 multicenter prospective studies Open

Marco Catarci, Giacomo Ruffo, Massimo Viola, Felice Pirozzi, Paolo Delrio , et al. · 2023

Background: Enhanced recovery after surgery (ERAS) offers lower overall morbidity rates and shorter hospital stay after colorectal surgery (CRS); high adherence rates to ERAS may significantly reduce major morbidity (MM), anastomotic leaka…

Blood Transfusions and Adverse Events after Colorectal Surgery: A Propensity-Score-Matched Analysis of a Hen–Egg Issue Open

Marco Catarci, Stefano Guadagni, Francesco Masedu, L Montemurro, Paolo Ciano , et al. · 2023

Blood transfusions are considered a risk factor for adverse outcomes after colorectal surgery. However, it is still unclear if they are the cause (the hen) or the consequence (the egg) of adverse events. A prospective database of 4529 colo…

Rivaroxaban vs placebo for extended antithrombotic prophylaxis after laparoscopic surgery for colorectal cancer Open

Cecilia Becattini, Ugo Pace, Felice Pirozzi, Annibale Donini, Giampiero Avruscio , et al. · 2022

The clinical benefit of extended prophylaxis for venous thromboembolism (VTE) after laparoscopic surgery for cancer is unclear. The efficacy and safety of direct oral anticoagulants for this indication are unexplored. PROphylaxis of venous…

Could Stoma Be Avoided after Laparoscopic Low Anterior Resection for Rectal Cancer? Experience with Transanal Tube in 195 Cases Open

Antonio Sciuto, Roberto Peltrini, Federica Andreoli, Andrea Gianmario Di Santo Albini, Maria Michela Di Nuzzo , et al. · 2022

Anastomotic leakage is the most-feared complication of rectal surgery. Transanal devices have been suggested for anastomotic protection as an alternative to defunctioning stoma, although evidence is conflicting, and no single device is wid…

Microsatellite Status Detection in Gastrointestinal Cancers: PCR/NGS Is Mandatory in Negative/Patchy MMR Immunohistochemistry Open

Federica Zito Marino, Martina Amato, Andrea Ronchi, Iacopo Panarese, Franca Ferraraccio , et al. · 2022

Background: Microsatellite instability (MSI) is a predictive biomarker for immune checkpoint inhibitors. The main goal was to investigate the discordance between IHC and PCR/NGS for MSI testing in gastrointestinal cancers. Methods: Two ser…

MDCT Findings in Gastrointestinal Perforations and the Predictive Value according to the Site of Perforation Open

Stefania Romano, Carmela Somma, Antonio Sciuto, Warissara Jutidamrongphan, Daniela Pacella , et al. · 2022

Background: Gastrointestinal perforations are a frequent cause of acute abdominal symptomatology for patients in the emergency department. The aim of this study was to investigate the findings of multidetector-row computed tomography of ga…

ERAS program adherence-institutionalization, major morbidity and anastomotic leakage after elective colorectal surgery: the iCral2 multicenter prospective study Open

Marco Catarci, Giacomo Ruffo, Massimo Viola, Felice Pirozzi, Paolo Delrio , et al. · 2021

Impact of neoadjuvant therapy followed by laparoscopic radical gastrectomy with D2 lymph node dissection in Western population: A multi‐institutional propensity score‐matched study Open

Umberto Bracale, Francesco Corcione, Giusto Pignata, Jacopo Andreuccetti, Pasquale Dolce , et al. · 2021

Background and Objectives In the setting of a minimally invasive approach, we aimed to compare short and long‐term postoperative outcomes of patients treated with neoadjuvant therapy (NAT) + surgery or upfront surgery in Western population…

Laparoscopic gastrectomy for stage II and III advanced gastric cancer: long‑term follow‑up data from a Western multicenter retrospective study Open

Umberto Bracale, Giovanni Merola, Giusto Pignata, Jacopo Andreuccetti, Pasquale Dolce , et al. · 2021

Introduction There has been an increasing interest for the laparoscopic treatment of early gastric cancer, especially among Eastern surgeons. However, the oncological effectiveness of Laparoscopic Gastrectomy (LG) for Advanced Gastric Canc…

ICG fluorescence imaging in colorectal surgery: a snapshot from the ICRAL study group Open

Gian Luca Baiocchi, Gianluca Guercioni, Nereo Vettoretto, Stefano Scabini, Paolo Millo , et al. · 2021

Laparoscopic segmental resection for tumours of the Angle of Treitz: a challenging but feasible surgical option. Results from a retrospective case-series analysis Open

Umberto Bracale, Emanuele Pontecorvi, Vania Silvestri, Diego Cuccurullo, Michele D’Ambra , et al. · 2020

Colorectal surgery in Italy during the Covid19 outbreak: a survey from the iCral study group Open

Marco Caricato, Gian Luca Baiocchi, Francesco Crafa, Stefano Scabini, Giuseppe Brisinda , et al. · 2020

Anastomotic leakage after elective colorectal surgery: a prospective multicentre observational study on use of the Dutch leakage score, serum procalcitonin and serum C-reactive protein for diagnosis Open

Marco Catarci, Giacomo Ruffo, Felice Borghi, Alberto Patriti, Paolo Delrio , et al. · 2020

Background The purpose of this study was to test use of the Dutch leakage score (DLS), serum C-reactive protein (CRP) and serum procalcitonin (PCT) in the diagnosis of anastomotic leakage (AL) after elective colorectal resection in a prosp…

Droplet digital PCR quantification of miR-1290 as a circulating biomarker for pancreatic cancer Open

Francesca Tavano, Domenica Gioffreda, Maria Rosa Valvano, Orazio Palmieri, Matteo Tardio , et al. · 2018

Genetic determinants of telomere length and risk of pancreatic cancer: A PANDoRA study Open

Daniele Campa, Martina Matarazzi, William Greenhalf, Maarten F. Bijlsma, Kai‐Uwe Saum , et al. · 2018

Telomere deregulation is a hallmark of cancer. Telomere length measured in lymphocytes (LTL) has been shown to be a risk marker for several cancers. For pancreatic ductal adenocarcinoma (PDAC) consensus is lacking whether risk is associate…

Predictive factors for anastomotic leakage after laparoscopic colorectal surgery Open

Antonio Sciuto, Giovanni Merola, Giovanni Domenico De Palma, Maurizio Sodo, Felice Pirozzi , et al. · 2018

Every colorectal surgeon during his or her career is faced with anastomotic leakage (AL); one of the most dreaded complications following any type of gastrointestinal anastomosis due to increased risk of morbidity, mortality, overall impac…

Lack of Association for Reported Endocrine Pancreatic Cancer Risk Loci in the PANDoRA Consortium Open

Daniele Campa, Ofure Obazee, Manuela Pastore, Francesco Panzuto, Valbona Liço , et al. · 2017

Background: Pancreatic neuroendocrine tumors (PNETs) are rare neoplasms for which very little is known about either environmental or genetic risk factors. Only a handful of association studies have been performed so far, suggesting a small…

Procalcitonin Reveals Early Dehiscence in Colorectal Surgery Open

Valentina Giaccaglia, Pier Federico Salvi, M. Antonelli, Giuseppe Nigri, Felice Pirozzi , et al. · 2015

PCT and CRP demonstrated to have a good negative predictive value for AL, both in 3rd and in 5th POD. Low levels of PCT, together with low CRP values, seem to be early and reliable markers of AL after colorectal surgery. These biomarkers m…

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