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View article: Initiating Empagliflozin and Sacubitril/Valsartan Early After Acute Myocardial Infarction: Mechanistic Study
Initiating Empagliflozin and Sacubitril/Valsartan Early After Acute Myocardial Infarction: Mechanistic Study Open
Background Empagliflozin and sacubitril/valsartan are established in heart failure treatment, but their effects after myocardial infarction (MI) are less clear. This study evaluated early empagliflozin initiation, with or without sacubitri…
View article: Outcomes of ventricular tachycardia ablation facilitated by pre-procedural cardiac imaging-derived scar characterization: a prospective multi-centre international registry
Outcomes of ventricular tachycardia ablation facilitated by pre-procedural cardiac imaging-derived scar characterization: a prospective multi-centre international registry Open
Aims Pre-procedural imaging can facilitate scar-related ventricular tachycardia (VT) ablation, although only limited data have been reported. This prospective registry aimed to analyse procedural data and outcomes in a multi-centre setting…
View article: Left Atrial Structure and Function Following Ethanol Infusion into Vein of Marshall (MR‐SHALL Study)
Left Atrial Structure and Function Following Ethanol Infusion into Vein of Marshall (MR‐SHALL Study) Open
Background Ethanol infusion into the vein of Marshall (EI‐VOM) is an adjunctive therapy to pulmonary vein isolation (PVI), which improves the efficacy of persistent atrial fibrillation (AF) ablation procedures. It is unknown how EI‐VOM sca…
View article: Design and deployment of the STEEER-AF trial to evaluate and improve guideline adherence: a cluster-randomized trial by the European Society of Cardiology and European Heart Rhythm Association
Design and deployment of the STEEER-AF trial to evaluate and improve guideline adherence: a cluster-randomized trial by the European Society of Cardiology and European Heart Rhythm Association Open
Aims The aim is to describe the rationale, design, delivery, and baseline characteristics of the Stroke prevention and rhythm control Treatment: Evaluation of an Educational programme of the European society of cardiology in a cluster-Rand…
View article: Diagnostic yield of a smartphone-operated, 6-lead device in Brugada syndrome
Diagnostic yield of a smartphone-operated, 6-lead device in Brugada syndrome Open
Background The spontaneous type 1 ECG pattern (ECG-T1) is diagnostic of Brugada syndrome (BrS) and implies an increased arrhythmic risk, while pharmacologically-induced ECG-T1 without other clinical features only makes the diagnosis possib…
View article: Tissue composition underlying local impedance in chronic infarction: an histological study
Tissue composition underlying local impedance in chronic infarction: an histological study Open
Background Local impedance (LI) mapping is feasible and provides additional tissue characterization of the ventricular tachycardia (VT) substrate. VT isthmuses are usually located in areas of intermediate LI while low LI regions did not ac…
View article: Implantation of a double allogeneic human engineered tissue graft on damaged heart: insights from the PERISCOPE phase I clinical trial
Implantation of a double allogeneic human engineered tissue graft on damaged heart: insights from the PERISCOPE phase I clinical trial Open
View article: Functional mapping to reveal slow conduction and substrate progression in atrial fibrillation
Functional mapping to reveal slow conduction and substrate progression in atrial fibrillation Open
Aims The aim of our study was to analyse the response to short-coupled atrial extrastimuli to identify areas of hidden slow conduction (HSC) and their relationship with the atrial fibrillation (AF) phenotype. Methods and results Twenty con…
View article: The effect of atrial morphology on atrial function in hypertrophic cardiomyopathy
The effect of atrial morphology on atrial function in hypertrophic cardiomyopathy Open
Background Atrial dysfunction is a relevant marker of disease progression in hypertrophic cardiomyopathy (HCM). Left atrial (LA) longitudinal functional parameters and volumes derived from cardiac magnetic resonance (CMR) are associated wi…
View article: Impact of vein of Marshall ethanol infusion on left atrial function: an MRI study
Impact of vein of Marshall ethanol infusion on left atrial function: an MRI study Open
Funding Acknowledgements Type of funding sources: None. Background Previous data suggested that left atrial (LA) function may be impaired by extensive atrial fibrillation (AF) ablation. Ethanol infusion of Vein of Marshall (EI-VOM) as an a…
View article: Anatomy of the isthmus: unraveling tissue composition of ventricular tachycardia diastolic pathway
Anatomy of the isthmus: unraveling tissue composition of ventricular tachycardia diastolic pathway Open
Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Spanish Ministry of Science and Innovation Background Unequal tissue composition of post-myocardial infarction (MI) scar (via…
View article: Ventricular tachycardia substrate ablation in patients with slightly depressed left ventricular ejection fraction. Predictors of VT-free survival in a prospective multicentre registry
Ventricular tachycardia substrate ablation in patients with slightly depressed left ventricular ejection fraction. Predictors of VT-free survival in a prospective multicentre registry Open
Funding Acknowledgements Type of funding sources: None. Background There is no consensus about the need for ICD implantation in patients with slightly depressed left ventricle ejection fraction (LVEF) after catheter ablation for hemodynami…
View article: CE-452773-4 ANATOMY OF THE ISTHMUS: UNRAVELING TISSUE COMPOSITION OF VENTRICULAR TACHYCARDIA DIASTOLIC PATHWAY
CE-452773-4 ANATOMY OF THE ISTHMUS: UNRAVELING TISSUE COMPOSITION OF VENTRICULAR TACHYCARDIA DIASTOLIC PATHWAY Open
View article: Worldwide survey on implantation of and outcomes for conduction system pacing with His bundle and left bundle branch area pacing leads
Worldwide survey on implantation of and outcomes for conduction system pacing with His bundle and left bundle branch area pacing leads Open
View article: Electrophysiological effects of adipose graft transposition procedure (AGTP) on the post-myocardial infarction scar: A multimodal characterization of arrhythmogenic substrate
Electrophysiological effects of adipose graft transposition procedure (AGTP) on the post-myocardial infarction scar: A multimodal characterization of arrhythmogenic substrate Open
Objective To assess the arrhythmic safety profile of the adipose graft transposition procedure (AGTP) and its electrophysiological effects on post-myocardial infarction (MI) scar. Background Myocardial repair is a promising treatment for p…
View article: Personalized assessment of the cumulative complication risk of the atrial fibrillation ablation track: The AF-TRACK calculator
Personalized assessment of the cumulative complication risk of the atrial fibrillation ablation track: The AF-TRACK calculator Open
The proposed risk model provides individualized estimates of the cumulative risk of complications of undergoing the AF ablation track. The AF-TRACK calculator is a validated, easy-to-use, Web-based clinical tool to calibrate the risk-to-be…
View article: Effect of MRI-Guided Fibrosis Ablation vs Conventional Catheter Ablation on Atrial Arrhythmia Recurrence in Patients With Persistent Atrial Fibrillation
Effect of MRI-Guided Fibrosis Ablation vs Conventional Catheter Ablation on Atrial Arrhythmia Recurrence in Patients With Persistent Atrial Fibrillation Open
ClinicalTrials.gov Identifier: NCT02529319.
View article: Negative SA-VA difference during entrainment of a supraventricular tachycardia: a new criterion for the diagnosis of focal atrial tachycardia
Negative SA-VA difference during entrainment of a supraventricular tachycardia: a new criterion for the diagnosis of focal atrial tachycardia Open
Funding Acknowledgements Type of funding sources: None. Introduction Ventricular overdrive pacing during tachycardia is one of the most common and useful maneuvers to assess de differential diagnosis of supraventricular tachycardia (SVT). …
View article: A Left sided site of origin is associated with adverse cardiovascular outcomes in patients with LV dysfunction undergoing PVC ablation
A Left sided site of origin is associated with adverse cardiovascular outcomes in patients with LV dysfunction undergoing PVC ablation Open
Funding Acknowledgements Type of funding sources: None. Background Epidemiological studies suggested that premature ventricular complexes (PVCs) are associated with cardiac mortality. But data are still inconclusive. Aim This study sought …
View article: Atrial tissue characterization by cardiac magnetic resonance and high-density mapping in patients with atrial fibrillation
Atrial tissue characterization by cardiac magnetic resonance and high-density mapping in patients with atrial fibrillation Open
Funding Acknowledgements Type of funding sources: None. BACKGROUND Left atrial fibrosis is a marker of atrial disease and it has an important role in the pathophysiology of atrial fibrillation (AF). Late gadolinium enhancement cardiac magn…
View article: Prospective evaluation of a hybrid clinical and electrocardiographic algorithm to predict the origin of outflow tract PVCs. A prospective multicenter study
Prospective evaluation of a hybrid clinical and electrocardiographic algorithm to predict the origin of outflow tract PVCs. A prospective multicenter study Open
Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): Beca de la Asociación del Ritmo Cardiaco para Formación en Investigación Post-Residencia en centros españoles. Background To predict the prema…
View article: Inappropriate shock in Brugada syndrome: incidence and predictors in patients with a subcutaneous implantable cardiac defibrillator
Inappropriate shock in Brugada syndrome: incidence and predictors in patients with a subcutaneous implantable cardiac defibrillator Open
Background: Subcutaneous implantable cardioverter defibrillators (S-ICDs) avoid complications secondary to transvenous leads, but inappropriate shocks (ISs) are frequent. Furthermore, IS data from patients with Brugada syndrome (BrS) with …
View article: Reduction in new cardiac electronic device implantations in Catalonia during COVID-19
Reduction in new cardiac electronic device implantations in Catalonia during COVID-19 Open
Aims During the COVID-19 pandemic, concern regarding its effect on the management of non-communicable diseases has been raised. However, there are no data on the impact on cardiac implantable electronic devices (CIED) implantation rates. W…
View article: Atrioventricular Node Ablation to Enhance Resynchronization Therapy Response in a Patient With Complete Atrioventricular Block
Atrioventricular Node Ablation to Enhance Resynchronization Therapy Response in a Patient With Complete Atrioventricular Block Open
View article: Magnetic Resonance Imaging-Guided Fibrosis Ablation for the Treatment of Atrial Fibrillation
Magnetic Resonance Imaging-Guided Fibrosis Ablation for the Treatment of Atrial Fibrillation Open
Background: Myocardial fibrosis is key for atrial fibrillation maintenance. We aimed to test the efficacy of ablating cardiac magnetic resonance (CMR)-detected atrial fibrosis plus pulmonary vein isolation (PVI). Methods: This was an open-…
View article: Transitioning from Preclinical to Clinical Heart Failure with Preserved Ejection Fraction: A Mechanistic Approach
Transitioning from Preclinical to Clinical Heart Failure with Preserved Ejection Fraction: A Mechanistic Approach Open
To better understand heart failure with preserved ejection fraction (HFpEF), we need to better characterize the transition from asymptomatic pre-HFpEF to symptomatic HFpEF. The current emphasis on left ventricular diastolic dysfunction mus…
View article: Atrial Failure as a Clinical Entity
Atrial Failure as a Clinical Entity Open
Atrial dysfunction has been widely considered a marker or consequence of other cardiac conditions rather than the cause itself. Here, we propose the term atrial failure as a clinically relevant entity, defined as any atrial dysfunction cau…
View article: Adipose graft transposition procedure: towards a novel strategy for myocardial scar and fibrosis reduction
Adipose graft transposition procedure: towards a novel strategy for myocardial scar and fibrosis reduction Open
Improvement in cell therapy efficiency by preventing: (i) myocar- dial damage and risk of ventricular arrhythmias from intramyocardial injection; (ii) migration of delivered stem cells into remote organs after systemic/intravenous administ…
View article: Ventricular fibrillation in a patient with Wolff‐Parkinson‐White syndrome unrelated to pre‐excited atrial fibrillation
Ventricular fibrillation in a patient with Wolff‐Parkinson‐White syndrome unrelated to pre‐excited atrial fibrillation Open
A 52‐year‐old man was admitted due to out‐hospital cardiac arrest. Recurrent ventricular fibrillation (VF) occurred under therapeutic hypothermia thereafter. Previously inadverted full pre‐excitation was documented exclusively and immediat…
View article: Preferential regional distribution of atrial fibrosis in posterior wall around left inferior pulmonary vein as identified by late gadolinium enhancement cardiac magnetic resonance in patients with atrial fibrillation
Preferential regional distribution of atrial fibrosis in posterior wall around left inferior pulmonary vein as identified by late gadolinium enhancement cardiac magnetic resonance in patients with atrial fibrillation Open
In patients with AF, the fibrotic area is preferentially located at the posterior wall and floor around the antrum of the left inferior pulmonary vein. Age >60 years was associated with increased fibrosis.