Explanipedia

Unravelling IPAF, VEDOSS and connective tissue diseases classifications through the mixed connective tissue disease spectrum Open

Kévin Chevalier, Benjamin Thoreau, Marc Michel, Bertrand Godeau, C. Agard , et al. · 2025

Background Mixed connective tissue disease (MCTD) has long been debated as an early nonspecific phase/symptom of differentiated connective tissue diseases (dCTD), similarly to interstitial pneumonia with autoimmune features (IPAF) and very…

Treatment of mixed connective tissue disease: A multicenter retrospective study Open

Kévin Chevalier, Benjamin Thoreau, Marc Michel, Bertrand Godeau, C. Agard , et al. · 2025

Pilot Study of Diagnostic Performances of Vascular Biomarkers Soluble fms-Like Tyrosine Kinase and Placental Growth Factor in Scleroderma Renal Crisis Open

A. Kante, Paul Legendre, Bérangère S. Joly, Bertrand Dunogué, Alexandre Hertig , et al. · 2024

Prevalent findings on low-dose CT scan lung cancer screening: a French prospective pilot study Open

Philippe Greniér, Maxence Arutkin, Anne‐Laure Brun, Anne-Cécile Métivier, Édouard Sage , et al. · 2024

Despite significant therapeutic advances, lung cancer remains the biggest killer among cancers. In France, there is no national screening program against lung cancer. Thus, in this perspective, the Foch Hospital decided to implement a pilo…

Tezepelumab for refractory eosinophilic granulomatosis with polyangiitis-related asthma Open

Nina Vincent-Galtié, Quentin Marquant, Émilie Catherinot, Félix Ackermann, A. Magnan , et al. · 2024

The CARMEN-France registry of adult patients with immune thrombocytopenia and autoimmune hemolytic anemia in France Open

Guillaume Moulis, Marc Michel, Bernard Bonnotte, Bertrand Godeau, Félix Ackermann , et al. · 2024

Can Haematological Parameters Discriminate COVID-19 from Influenza? Open

Sahar Gnaba, Dmitry Sukhachev, Tiffany Pascreau, Félix Ackermann, Frédérique Delcominette , et al. · 2023

Symptoms of COVID-19 are similar to the influenza virus, but because treatments and prognoses are different, it is important to accurately and rapidly differentiate these diseases. The aim of this study was to evaluate whether the analysis…

Stratification of COVID-19 Severity Using SeptiCyte RAPID, a Novel Host Immune Response Test Open

Victor Gravrand, François Mellot, Félix Ackermann, Marie‐Christine Ballester, Benjamin Zuber , et al. · 2023

SeptiCyte® RAPID is a gene expression assay measuring the relative expression levels of host response genes PLA2G7 and PLAC8, indicative of a dysregulated immune response during sepsis. As severe forms of COVID-19 may be considered viral s…

Cutaneous Involvement in Catastrophic Antiphospholipid Syndrome in a Multicenter Cohort of 65 Patients Open

Anastasia Dupré, Nathalie Morel, Cécile Yelnik, Philippe Moguelet, Véronique Le Guern , et al. · 2022

Importance Catastrophic antiphospholipid syndrome (CAPS) is a severe, rare complication of antiphospholipid syndrome (APS), but cutaneous involvement has not yet been adequately described. Objective To describe cutaneous involvement during…

Stratification of COVID-19 severity using SeptiCyte RAPID, a novel host immune response test Open

Victor Gravrand, François Mellot, Félix Ackermann, Marie‐Christine Ballester, Benjamin Zuber , et al. · 2022

SeptiCyte ® RAPID is a gene expression assay measuring the relative expression levels of host response genes PLA2G7 and PLAC8, indicative of a dysregulated immune response during sepsis. As severe forms of COVID-19 may be considered viral …

Soluble CD163 and incident cardiovascular events in patients with systemic lupus erythematosus: An observational cohort study Open

C. David, N. Costedoat‐Chalumeau, Drifa Belhadi, Cédric Laouénan, Anne Boutten , et al. · 2022

International audience

Vaccine refusal and burnout: Hospitals need “emergency multidisciplinary team meetings” Open

Henri‐Corto Stoeklé, Félix Ackermann, Philippe Beuzeboc, Christian Hervé · 2022

Why and how should hospitals respond when faced with patients and healthcare workers refusing to be vaccinated against COVID-19 or suffering from burnout? Hospitals need more practical solutions for the concrete management of ethical issue…

Tocilizumab plus dexamethasone versus dexamethasone in patients with moderate-to-severe COVID-19 pneumonia: A randomised clinical trial from the CORIMUNO-19 study group Open

Olivier Hermine, Xavier Mariette, Raphaël Porcher, Félix Djossou, Yann Nguyen , et al. · 2022

Clonal haematopoiesis of indeterminate potential and cardiovascular events in systemic lupus erythematosus (HEMATOPLUS study) Open

C. David, Nicolas Duployez, Philippine Eloy, Drifa Belhadi, J. Chezel , et al. · 2022

Objective The detection of somatic mutations among the genes of myeloid cells in asymptomatic patients—defining clonal haematopoiesis of indeterminate potential (CHIP)—is associated with a predisposition to cardiovascular events (CVEs) in …

»Der Genozid am Belarusischen Volk« als politischer Diskurs und Strafverfolgungspraxis Open

Félix Ackermann · 2021

In diesem Beitrag wird die Verbindung zwischen offizieller Geschichtspolitik der Republik Belarus und der Verfolgung von Anhängern:innen der Protestbewegung beleuchtet. Im Mittelpunkt steht die Frage, wie das sowjetische Narrativ vom Genoz…

Venous thromboembolism during systemic inflammatory and autoimmune diseases associated with myelodysplastic syndromes, chronic myelomonocytic leukaemia and myelodysplastic/myeloproliferative neoplasms: a French multicentre retrospective case-control study Open

Marie Péan de Ponfilly-Sotier, Vincent Jachiet, Y. Benhamou, Constance Lahuna, Benoît de Renzis , et al. · 2021

VTE is a common complication in MDS/CMML-associated SIADSs with an increased risk of bleeding when treated by anticoagulants. In the MDS/CMML subgroup, SIADS flares and MDS/CMML progression seem to be prothrombotic risk factors.

Regression of Coronary Aneurysms With Intravenous Immunoglobulins and Steroids for COVID-19 Adult Multisystem Inflammatory Syndrome Open

Sarah Diakite, Nadine Bousdira, Guillaume Tachon, Félix Ackermann, Matthieu Groh , et al. · 2021

High levels of TNFα in patients with COVID-19 refractory to tocilizumab Open

François‐Xavier Danlos, Félix Ackermann, Julien Rohmer, Mathilde Roumier, Aurélien Marabelle , et al. · 2021

Venous thrombosis and predictors of relapse in eosinophil-related diseases Open

Valériane Réau, Alexandre Vallée, Benjamin Terrier, Aurélie Plessier, Noémie Abisror , et al. · 2021

Eosinophils have widespread procoagulant effects. Eosinophilic cardiovascular toxicity mostly consists of endomyocardial damage or eosinophilic vasculitis, while reported cases of venous thrombosis (VT) are scarce. We aimed to report on th…

A low level of CD16<sup>pos</sup> monocytes in SARS-CoV-2 infected patients is a marker of severity Open

Marc Vasse, Benjamin Zuber, Laurie Goubeau, Marie‐Christine Ballester, Mathilde Roumier , et al. · 2021

Objectives Severe forms of coronavirus disease 2019 (COVID-19) are characterized by an excessive production of inflammatory cytokines. Activated monocytes secrete high levels of cytokines. Human monocytes are divided into three major popul…

Tocilizumab for Severe Worsening COVID-19 Pneumonia: a Propensity Score Analysis Open

Mathilde Roumier, Romain Paule, Alexandre Vallée, Julien Rohmer, Marie Ballester , et al. · 2020

Clinical course of COVID-19 in a cohort of 342 familial Mediterranean fever patients with a long-term treatment by colchicine in a French endemic area Open

R. Bourguiba, M. Delplanque, Caroline Vinit, Félix Ackermann, Léa Savey , et al. · 2020

Hydroxychloroquine levels in patients with systemic lupus erythematosus: whole blood is preferable but serum levels also detect non-adherence Open

Benoı̂t Blanchet, M. Jallouli, Marie Allard, Pascale Ghillani‐Dalbin, Lionel Galicier , et al. · 2020

Evaluation of two serum free light chain quantitation methods, Freelite and Seralite, in the clinical laboratory with a view to switching immunoassay Open

Jennifer Heaney, Félix Ackermann, Michèle Paunet-Bobo, Souad Mehlal, Émilie Jolly , et al. · 2020

COVID-19 in lung-transplanted and cystic fibrosis patients: Be careful Open

Éric Farfour, C. Picard, L. Beaumont, Philippe Lesprit, Marie‐Christine Ballester , et al. · 2020

Interleukin-6 blockade for severe COVID-19 Open

Mathilde Roumier, Romain Paule, Matthieu Groh, Alexandre Vallée, Félix Ackermann · 2020

In the context of COVID-19 pandemic and growing tensions worldwide regarding healthcare facilities, there is an urgent need for effective treatments likely to reduce the crunch of ICU beds. Following the assumption by Mehta and colleagues …

Risk factors for hydroxychloroquine retinopathy in systemic lupus erythematosus: a case–control study with hydroxychloroquine blood-level analysis Open

Tiphaine Lenfant, S. Ben Salah, Gaëlle Leroux, Elodie Bousquet, Véronique Le Guern , et al. · 2020

Objective HCQ is an essential medication in SLE, proven to lengthen survival and reduce flares. Its use, however, is limited by its rare but severe ophthalmological complications. Here, we aimed to analyse factors associated with HCQ retin…

Tocilizumab to Prevent Ventilatory Support for Severe Worsening COVID-19 Pneumonia: A Propensity Score Analysis Open

Mathilde Roumier, Romain Paule, Alexandre Vallée, Julien Rohmer, Marie Ballester , et al. · 2020

The history of the future closure of Brygidki: 150 years of discussion to move the penitentiary outside of Lviv Open

Félix Ackermann · 2019

This text will go back to the 19th century in order to show that the discussion about moving Brygidki to another location started as early as the 1870s when it turned out that the very materiality of the former convent prevented the legal …

Territorialisation and Incarceration: The Nexus between Solitary Confinement, Religious Praxis and Imperial Rule in Nineteenth-Century Poland and Lithuania Open

Félix Ackermann · 2019

Modern prisons are viewed in this paper as highly specific configurations, providing a critical infrastructure for the forging of a new relationship between subjects and the imperial state. The comparison of three rather different temporal…

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