Phuc Félix Nguyen‐Tan
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View article: Surrogate endpoints in clinical trials of p16-positive squamous cell carcinoma of the oropharynx: an individual patient data meta-analysis
Surrogate endpoints in clinical trials of p16-positive squamous cell carcinoma of the oropharynx: an individual patient data meta-analysis Open
View article: Data from Nomogram to Predict the Benefit of Intensive Treatment for Locoregionally Advanced Head and Neck Cancer
Data from Nomogram to Predict the Benefit of Intensive Treatment for Locoregionally Advanced Head and Neck Cancer Open
Purpose:Previous studies indicate that the benefit of therapy depends on patients' risk for cancer recurrence relative to noncancer mortality (ω ratio). We sought to test the hypothesis that patients with head and neck cancer (HNC) with a …
View article: Supplementary Data from Nomogram to Predict the Benefit of Intensive Treatment for Locoregionally Advanced Head and Neck Cancer
Supplementary Data from Nomogram to Predict the Benefit of Intensive Treatment for Locoregionally Advanced Head and Neck Cancer Open
Supplementary Data: Tables S1-S2; Figures S1-S4
View article: Supplementary Data from Nomogram to Predict the Benefit of Intensive Treatment for Locoregionally Advanced Head and Neck Cancer
Supplementary Data from Nomogram to Predict the Benefit of Intensive Treatment for Locoregionally Advanced Head and Neck Cancer Open
Supplementary Data: Tables S1-S2; Figures S1-S4
View article: Data from Nomogram to Predict the Benefit of Intensive Treatment for Locoregionally Advanced Head and Neck Cancer
Data from Nomogram to Predict the Benefit of Intensive Treatment for Locoregionally Advanced Head and Neck Cancer Open
Purpose:Previous studies indicate that the benefit of therapy depends on patients' risk for cancer recurrence relative to noncancer mortality (ω ratio). We sought to test the hypothesis that patients with head and neck cancer (HNC) with a …
View article: Comparing 3D deformations between longitudinal daily CBCT acquisitions using CNN for head and neck radiotherapy toxicity prediction
Comparing 3D deformations between longitudinal daily CBCT acquisitions using CNN for head and neck radiotherapy toxicity prediction Open
Adaptive radiotherapy is a growing field of study in cancer treatment due to it's objective in sparing healthy tissue. The standard of care in several institutions includes longitudinal cone-beam computed tomography (CBCT) acquisitions to …
View article: Long-Term Update of NRG/RTOG 0522: A Randomized Phase 3 Trial of Concurrent Radiation and Cisplatin With or Without Cetuximab in Locoregionally Advanced Head and Neck Cancer
Long-Term Update of NRG/RTOG 0522: A Randomized Phase 3 Trial of Concurrent Radiation and Cisplatin With or Without Cetuximab in Locoregionally Advanced Head and Neck Cancer Open
View article: Magnetic Resonance-Guided Radiation Therapy for Head and Neck Cancers
Magnetic Resonance-Guided Radiation Therapy for Head and Neck Cancers Open
Despite the significant evolution of radiation therapy (RT) techniques in recent years, many patients with head and neck cancer still experience significant toxicities during and after treatments. The increased soft tissue contrast and fun…
View article: Combining dense elements with attention mechanisms for 3D radiotherapy dose prediction on head and neck cancers
Combining dense elements with attention mechanisms for 3D radiotherapy dose prediction on head and neck cancers Open
Purpose External radiation therapy planning is a highly complex and tedious process as it involves treating large target volumes, prescribing several levels of doses, as well as avoiding irradiating critical structures such as organs at ri…
View article: Cross-institutional outcome prediction for head and neck cancer patients using self-attention neural networks
Cross-institutional outcome prediction for head and neck cancer patients using self-attention neural networks Open
In radiation oncology, predicting patient risk stratification allows specialization of therapy intensification as well as selecting between systemic and regional treatments, all of which helps to improve patient outcome and quality of life…
View article: Upfront DPYD Genotyping and Toxicity Associated with Fluoropyrimidine-Based Concurrent Chemoradiotherapy for Oropharyngeal Carcinomas: A Work in Progress
Upfront DPYD Genotyping and Toxicity Associated with Fluoropyrimidine-Based Concurrent Chemoradiotherapy for Oropharyngeal Carcinomas: A Work in Progress Open
Background: 5-FU-based chemoradiotherapy (CRT) could be associated with severe treatment-related toxicities in patients harboring at-risk DPYD polymorphisms. Methods: The studied population included consecutive patients with locoregionally…
View article: 863MO Nomogram for predicting survival for patients receiving definitive chemoradiation in locally advanced squamous cell carcinoma of the head and neck: A secondary analysis of NRG/RTOG 0129, 0522, and 1016
863MO Nomogram for predicting survival for patients receiving definitive chemoradiation in locally advanced squamous cell carcinoma of the head and neck: A secondary analysis of NRG/RTOG 0129, 0522, and 1016 Open
View article: The impact of age on outcome in phase III NRG Oncology/RTOG trials of radiotherapy (XRT) +/− systemic therapy in locally advanced head and neck cancer
The impact of age on outcome in phase III NRG Oncology/RTOG trials of radiotherapy (XRT) +/− systemic therapy in locally advanced head and neck cancer Open
View article: Risk groups of laryngeal cancer treated with chemoradiation according to nomogram scores – A pooled analysis of RTOG 0129 and 0522
Risk groups of laryngeal cancer treated with chemoradiation according to nomogram scores – A pooled analysis of RTOG 0129 and 0522 Open
View article: Dual Inhibition of Autophagy and PI3K/AKT/MTOR Pathway as a Therapeutic Strategy in Head and Neck Squamous Cell Carcinoma
Dual Inhibition of Autophagy and PI3K/AKT/MTOR Pathway as a Therapeutic Strategy in Head and Neck Squamous Cell Carcinoma Open
Genomic analyses of head and neck squamous cell carcinoma (HNSCC) have highlighted alterations in the phosphatidylinositol 3-kinase (PI3K) signaling pathway, presenting a therapeutic target for multiple ongoing clinical trials with PI3K or…
View article: Incidence of osteoradionecrosis of the jaws: A retrospective study of 620 head and neck cancer patients treated by radiotherapy
Incidence of osteoradionecrosis of the jaws: A retrospective study of 620 head and neck cancer patients treated by radiotherapy Open
Background This study aims to assess systemic and local risk factors influencing the development of osteoradionecrosis of the jaws (ORN) and its incidence in head and neck cancer patients undergoing radiotherapy.Methods This was a retrospe…
View article: Single Nucleotide Polymorphism rs6942067 Is a Risk Factor in Young and in Non-Smoking Patients with HPV Negative Head and Neck Squamous Cell Carcinoma
Single Nucleotide Polymorphism rs6942067 Is a Risk Factor in Young and in Non-Smoking Patients with HPV Negative Head and Neck Squamous Cell Carcinoma Open
Genetic factors behind the increasing incidence of human papillomavirus (HPV) negative head and neck squamous cell carcinoma (HNSCC) in young non-smokers are suspected, but have not been identified. Recently, rs6942067, a single nucleotide…
View article: A Nomogram for Outcomes after Chemoradiation for Non-HPV-Related Squamous Cell Carcinomas of the Head and Neck – A Pooled Analysis of NRG Oncology RTOG 0129 and 0522
A Nomogram for Outcomes after Chemoradiation for Non-HPV-Related Squamous Cell Carcinomas of the Head and Neck – A Pooled Analysis of NRG Oncology RTOG 0129 and 0522 Open
View article: Nomogram to Predict the Benefit of Intensive Treatment for Locoregionally Advanced Head and Neck Cancer
Nomogram to Predict the Benefit of Intensive Treatment for Locoregionally Advanced Head and Neck Cancer Open
Purpose: Previous studies indicate that the benefit of therapy depends on patients' risk for cancer recurrence relative to noncancer mortality (ω ratio). We sought to test the hypothesis that patients with head and neck cancer (HNC) with a…
View article: Pre-irradiation dental care: Ready-to-use templates for oropharyngeal cancers
Pre-irradiation dental care: Ready-to-use templates for oropharyngeal cancers Open
Pre-RT dose distribution templates are an objective way to prepare PIDC. Further studies with a larger cohort are needed to validate these templates.
View article: Phase 1-2 Study of De-intensified IMRT and Concurrent Chemotherapy in Locally Advanced Oropharyngeal Carcinoma
Phase 1-2 Study of De-intensified IMRT and Concurrent Chemotherapy in Locally Advanced Oropharyngeal Carcinoma Open
View article: Aetiological heterogeneity of head and neck squamous cell carcinomas: the role of human papillomavirus infections, smoking and alcohol
Aetiological heterogeneity of head and neck squamous cell carcinomas: the role of human papillomavirus infections, smoking and alcohol Open
Tobacco and alcohol consumption are the main risk factors for head and neck squamous cell carcinoma (HNSCC). In addition, human papillomavirus (HPV) infection plays a causal role in oropharyngeal cancer (OPC), a subset of HNSCC. We assesse…
View article: Radiomics strategies for risk assessment of tumour failure in head-and-neck cancer
Radiomics strategies for risk assessment of tumour failure in head-and-neck cancer Open
This collection is a copy of the original publication. The zipped file is stored conveniently in a zipped file for a project I am working on.
View article: Radiomics strategies for risk assessment of tumour failure in head-and-neck cancer
Radiomics strategies for risk assessment of tumour failure in head-and-neck cancer Open
View article: Radiomics strategies for risk assessment of tumour failure in head-and-neck cancer
Radiomics strategies for risk assessment of tumour failure in head-and-neck cancer Open
Quantitative extraction of high-dimensional mineable data from medical images is a process known as radiomics. Radiomics is foreseen as an essential prognostic tool for cancer risk assessment and the quantification of intratumoural heterog…
View article: The <i>KRAS</i>-Variant and Cetuximab Response in Head and Neck Squamous Cell Cancer
The <i>KRAS</i>-Variant and Cetuximab Response in Head and Neck Squamous Cell Cancer Open
clinicaltrials.gov Identifier: NCT00265941.
View article: Exploratory Factor Analysis of NRG Oncology's University of Washington Quality of Life Questionnaire—RTOG Modification
Exploratory Factor Analysis of NRG Oncology's University of Washington Quality of Life Questionnaire—RTOG Modification Open
View article: Quality of Life and Performance Status From a Substudy Conducted Within a Prospective Phase 3 Randomized Trial of Concurrent Accelerated Radiation Plus Cisplatin With or Without Cetuximab for Locally Advanced Head and Neck Carcinoma: NRG Oncology Radiation Therapy Oncology Group 0522
Quality of Life and Performance Status From a Substudy Conducted Within a Prospective Phase 3 Randomized Trial of Concurrent Accelerated Radiation Plus Cisplatin With or Without Cetuximab for Locally Advanced Head and Neck Carcinoma: NRG Oncology Radiation Therapy Oncology Group 0522 Open
View article: Quality of Life and Performance Status From a Substudy Conducted Within a Prospective Phase 3 Randomized Trial of Concurrent Standard Radiation Versus Accelerated Radiation Plus Cisplatin for Locally Advanced Head and Neck Carcinoma: NRG Oncology RTOG 0129
Quality of Life and Performance Status From a Substudy Conducted Within a Prospective Phase 3 Randomized Trial of Concurrent Standard Radiation Versus Accelerated Radiation Plus Cisplatin for Locally Advanced Head and Neck Carcinoma: NRG Oncology RTOG 0129 Open
View article: Prognostic Value of p16 Status on the Development of a Complete Response in Involved Oropharynx Cancer Neck Nodes After Cisplatin-Based Chemoradiation: A Secondary Analysis of NRG Oncology RTOG 0129
Prognostic Value of p16 Status on the Development of a Complete Response in Involved Oropharynx Cancer Neck Nodes After Cisplatin-Based Chemoradiation: A Secondary Analysis of NRG Oncology RTOG 0129 Open