Explanipedia

Associations of night sleep duration and daytime napping with diabetic retinopathy in patients with type 2 diabetes Open

Lei Xi, Xiaohui Sun, Zhimin Feng, Yanan Cao · 2025

Aims The purpose of this study was to evaluate the relationship between night sleep duration, daytime napping, and diabetic retinopathy (DR) in type 2 diabetes (T2D) patients and to explore the potential mediating role of metabolic factors…

Sleep Phenotypes, Genetic Susceptibility, and Risk of Obesity in Patients With Type 2 Diabetes: A National Prospective Cohort Study Open

Lei Xi, Li Li, Songbo Fu, Yuancheng Dai, Juan Shi , et al. · 2025

Background To determine the associations between sleep phenotypes and the risks of specific obesity types and weight gain in patients with type 2 diabetes (T2D), especially in different genetic risk groups. Materials and Methods We conduct…

Anomalous traffic identification method for POST messages based on gambling website templates Open

Zhimin Feng, Dezhi Han, Songyang Wu, Wenqi Sun, Shuxin Shi · 2024

Malicious websites pose significant social risks, necessitating automatic, efficient, and accurate identification methods. This paper proposes a POST traffic classification method based on website templates to identify abnormal traffic fro…

COVID-19 plasma exosomes promote proinflammatory immune responses in peripheral blood mononuclear cells Open

Lechuang Chen, Rui Chen, Min Yao, Zhimin Feng, Guoxiang Yuan , et al. · 2022

Elevated serum cytokine production in COVID-19 patients is associated with disease progression and severity. However, the stimuli that initiate cytokine production in patients remain to be fully revealed. Virus-infected cells release virus…

COVID-19 plasma exosomes promote pro-inflammatory immune responses in peripheral blood mononuclear cells Open

Lechuang Chen, Rui Chen, Min Yao, Zhimin Feng, Guoxiang Yuan , et al. · 2022

Elevated serum cytokine production in COVID-19 patients is associated with disease progression and severity. However, the stimulus that initiates cytokine production in patients remains to be fully revealed. Virus-infected cells can releas…

COVID-19 plasma exosomes promote pro-inflammatory immune responses in peripheral blood mononuclear cells Open

Lechuang Chen, Rui Chen, Min Yao, Zhimin Feng, Guoxiang Yuan , et al. · 2022

Elevated serum cytokine production in COVID-19 patients associates with disease progression and severity. However, the stimulus that initiates cytokine production in patients remains to be fully revealed. Virus-infected cells can release v…

The ChinaMAP reference panel for the accurate genotype imputation in Chinese populations Open

Lin Li, Peide Huang, Xiaohui Sun, Siyu Wang, Min Xu , et al. · 2021

The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals Open

Yanan Cao, Lin Li, Min Xu, Zhimin Feng, Xiaohui Sun , et al. · 2020

Comparative genetic analysis of the novel coronavirus (2019-nCoV/SARS-CoV-2) receptor ACE2 in different populations Open

Yanan Cao, Lin Li, Zhimin Feng, Shengqing Wan, Peide Huang , et al. · 2020

Human Immunodeficiency Virus-Associated Exosomes Promote Kaposi’s Sarcoma-Associated Herpesvirus Infection via the Epidermal Growth Factor Receptor Open

Lechuang Chen, Zhimin Feng, Guoxiang Yuan, Corey C. Emerson, Phoebe L. Stewart , et al. · 2020

Kaposi’s sarcoma-associated herpesvirus (KSHV) is the causal agent for Kaposi’s sarcoma (KS), the most common malignancy in HIV/AIDS patients. Oral transmission through saliva is considered the most common route for spreading the virus amo…

Identification of second primary tumors from lung metastases in patients with esophageal squamous cell carcinoma using whole-exome sequencing Open

Liyan Xue, Lin Li, Xinyi Fan, Zitong Zhao, Wei Zhou , et al. · 2020

Esophageal squamous cell carcinoma (ESCC) patients with a synchronous or metachronous lung tumor can be diagnosed with lung metastasis (LM) or a second primary tumor (SPT), but the accurate discrimination between LM and SPT remains a clini…

Kaposi sarcoma-associated herpesvirus infection in HIV patients: potential role of HIV-associated extracellular vesicles Open

Lechuang Chen, Zhimin Feng, Guoxiang Yuan, Benjamin Reinthal, Fengchun Ye , et al. · 2019

Kaposi sarcoma-associated herpesvirus (KSHV) is the causal agent for Kaposi sarcoma (KS), the most common malignancy in people living with HIV/AIDS. The oral cavity is a major route for KSHV infection and transmission. However, how KSHV br…

Exosomes derived from HIV-1-infected cells promote growth and progression of cancer via HIV TAR RNA Open

Lechuang Chen, Zhimin Feng, Hong Yue, Douglas A. Bazdar, Uri Mbonye , et al. · 2018

People living with HIV/AIDS on antiretroviral therapy have increased risk of non-AIDS-defining cancers (NADCs). However, the underlying mechanism for development and progression of certain NADCs remains obscure. Here we show that exosomes …

Conceptual Perspectives: Bacterial Antimicrobial Peptide Induction as a Novel Strategy for Symbiosis with the Human Host Open

Santosh K. Ghosh, Zhimin Feng, Hisashi Fujioka, Renate Lux, Thomas S. McCormick , et al. · 2018

Human beta defensins (hBDs) are small cationic peptides, expressed in mucosal epithelia and important agents of innate immunity, act as antimicrobial and chemotactic agents at mucosal barriers. In this perspective, we present evidence supp…

Comprehensive genomic analysis of Oesophageal Squamous Cell Carcinoma reveals clinical relevance Open

Peina Du, Peide Huang, Xuanlin Huang, Xiangchun Li, Zhimin Feng , et al. · 2017

Human beta-defensins 2 and -3 cointernalize with human immunodeficiency virus via heparan sulfate proteoglycans and reduce infectivity of intracellular virions in tonsil epithelial cells Open

Rossana Herrera, Michael B. Morris, Kristina W. Rosbe, Zhimin Feng, Aaron Weinberg , et al. · 2015

HBD-3 induces NK cell activation, IFN-γ secretion and mDC dependent cytolytic function Open

Chelsey J. Judge, Elane Reyes-Avilés, Sara J. Conry, Scott F. Sieg, Zhimin Feng , et al. · 2015

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