Feng‐Chang Lin
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View article: An Electronic Health Record Algorithm's Performance to Identify Cognitive Impairment in Primary Care
An Electronic Health Record Algorithm's Performance to Identify Cognitive Impairment in Primary Care Open
Optimization of an EHR algorithm to detect cognitive impairment by combining cognitive impairment-related ICD-10 codes and dementia medications identified people with dementia or mild cognitive impairment in primary care with high specific…
View article: Epidemiology of ovale, vivax and falciparum malaria in the highlands of Cameroon: An integrated community survey of human infection and vector abundance
Epidemiology of ovale, vivax and falciparum malaria in the highlands of Cameroon: An integrated community survey of human infection and vector abundance Open
Despite global malaria control efforts, the disease caused 263 million cases and 597,000 deaths in 2023. While Plasmodium falciparum accounts for most cases in Africa, non-falciparum species, such as P. ovale spp. and P. vivax, can cause r…
View article: Epidemiology of ovale, vivax and falciparum malaria in the highlands of Cameroon: An integrated community survey of human infection and vector abundance
Epidemiology of ovale, vivax and falciparum malaria in the highlands of Cameroon: An integrated community survey of human infection and vector abundance Open
Despite global malaria control efforts, the disease caused 263 million cases and 597,000 deaths in 2023. While Plasmodium falciparum accounts for most cases in Africa, non-falciparum species, such as P. ovale spp . and P. vivax , can cause…
View article: A Comparison of Piperacillin-Tazobactam With Conventional Antibiotics for Prophylaxis in Lower Extremity Type III Open Fractures
A Comparison of Piperacillin-Tazobactam With Conventional Antibiotics for Prophylaxis in Lower Extremity Type III Open Fractures Open
View article: Frailty Trajectories and Social Determinants of Health of Older Adults in Rural and Urban Areas in the U.S.
Frailty Trajectories and Social Determinants of Health of Older Adults in Rural and Urban Areas in the U.S. Open
Older adults, aged 65 years and older, develop and experience frailty at different rates. Yet, this heterogeneity is not well understood, nor are the factors, such as geographical residence, that influence different frailty trajectories an…
View article: High mortality rates after distal femur fractures in patients with end-stage renal disease
High mortality rates after distal femur fractures in patients with end-stage renal disease Open
Objectives: Hip fractures in patients with end-stage renal disease (ESRD) are associated with high mortality rates. The effect of ESRD on mortality after operative treatment of distal femur fractures is not known. Our hypothesis was that d…
View article: Effects of Exercise Snacks on Cardiometabolic Health and Body Composition in Adults: A Systematic Review and Meta‐Analysis
Effects of Exercise Snacks on Cardiometabolic Health and Body Composition in Adults: A Systematic Review and Meta‐Analysis Open
This systematic review and meta‐analysis aims to investigate the impact of exercise snacks (ExSn), which involve incorporating short bursts of high‐intensity physical activity into daily routines, on improving cardiometabolic health and bo…
View article: An Enhanced Social Network Strategy to Increase the Uptake of HIV Services: Protocol for Type I Hybrid Implementation Study (Carolinas RESPOND)
An Enhanced Social Network Strategy to Increase the Uptake of HIV Services: Protocol for Type I Hybrid Implementation Study (Carolinas RESPOND) Open
Background In the United States, persisting new HIV diagnoses among gay, bisexual, and other cisgender men who have sex with men (GBMSM) and transgender women make it unlikely that the United States will meet the Ending the HIV Epidemic’s …
View article: Identifying Older Adults at Risk of Accelerated Decline in Gait Speed and Grip Strength: Insights from the National Health and Aging Trends Study (NHATS)
Identifying Older Adults at Risk of Accelerated Decline in Gait Speed and Grip Strength: Insights from the National Health and Aging Trends Study (NHATS) Open
Gait speed and grip strength are widely used measures of physical function in older adults and are predictive of disability, hospitalization, and mortality. However, there is a limited understanding of the long-term trajectories of these m…
View article: Identifying Older Adults at Risk of Accelerated Decline in Gait Speed and Grip Strength: Insights from the National Health and Aging Trends Study (NHATS)
Identifying Older Adults at Risk of Accelerated Decline in Gait Speed and Grip Strength: Insights from the National Health and Aging Trends Study (NHATS) Open
Gait speed and grip strength are widely used measures of physical function in older adults and are predictive of disability, hospitalization, and mortality. However, there is a limited understanding of the long-term trajectories of these m…
View article: Children with hepatitis B virus infections, Democratic Republic of the Congo
Children with hepatitis B virus infections, Democratic Republic of the Congo Open
Our investigation highlights the importance of subnational prevalence estimates in large countries such as the Democratic Republic of the Congo, and we have identified regions that may benefit from improved childhood vaccination delivery s…
View article: The Association of Neonatal Respiratory Distress With Ciliary Ultrastructure and Genotype in Primary Ciliary Dyskinesia
The Association of Neonatal Respiratory Distress With Ciliary Ultrastructure and Genotype in Primary Ciliary Dyskinesia Open
Objective To evaluate the relationship between ciliary ultrastructure/genotype and prevalence of neonatal respiratory distress (NRD) in primary ciliary dyskinesia (PCD). Study Design This was a retrospective analysis from a multicenter, pr…
View article: Epidemiology of Relapsing and Falciparum Malaria in the Highlands of Cameroon: An Integrated Community Survey of Human Infection and Vector Abundance
Epidemiology of Relapsing and Falciparum Malaria in the Highlands of Cameroon: An Integrated Community Survey of Human Infection and Vector Abundance Open
Despite global malaria control efforts, the disease caused 263 million cases and 597,000 deaths in 2023. While Plasmodium falciparum accounts for most cases in Africa, non-falciparum species, such as P. ovale spp. and P. vivax , can cause …
View article: A discrete-time split-state framework for multi-state modeling with application to describing the course of heart disease
A discrete-time split-state framework for multi-state modeling with application to describing the course of heart disease Open
View article: Disparities in the utilization of genetic testing for non‐acquired infantile epileptic spasms syndrome in a single healthcare center in North Carolina
Disparities in the utilization of genetic testing for non‐acquired infantile epileptic spasms syndrome in a single healthcare center in North Carolina Open
Objective To investigate disparities in the utilization of genetic sequencing among children with Infantile Epileptic Spasms Syndrome (IESS), a severe early‐onset epilepsy where timely diagnosis and treatment are crucial for improving neur…
View article: Fitting cure models using pseudo-observations approaches with the R package pseudoCure
Fitting cure models using pseudo-observations approaches with the R package pseudoCure Open
In survival analysis, it is traditionally assumed that all individuals are susceptible to the event of interest given sufficient time, a premise supported by well-established statistical software. However, scenarios exist where a considera…
View article: Progression of Otologic and Nasal Symptoms in Primary Ciliary Dyskinesia Throughout Childhood
Progression of Otologic and Nasal Symptoms in Primary Ciliary Dyskinesia Throughout Childhood Open
Objective Primary ciliary dyskinesia (PCD) is characterized by upper and lower airway disease. Multiple studies have demonstrated the progression of pulmonary disease; however, longitudinal changes in the otologic and nasal symptoms have n…
View article: Effects of Pharmacologic, Lifestyle, and Combined Interventions on Body Composition and Metabolic Health in Women with Excess Adiposity and Polycystic Ovary Syndrome: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials
Effects of Pharmacologic, Lifestyle, and Combined Interventions on Body Composition and Metabolic Health in Women with Excess Adiposity and Polycystic Ovary Syndrome: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials Open
View article: Investigating context-specific sedentary behaviours and cardiometabolic health in college-based young adults (CONTEXT-SB): a protocol for a longitudinal observational study
Investigating context-specific sedentary behaviours and cardiometabolic health in college-based young adults (CONTEXT-SB): a protocol for a longitudinal observational study Open
Background Sedentary behaviour (SB) is detrimental to cardiometabolic disease (CMD) risk, which can begin in young adulthood. To devise effective SB-CMD interventions in young adults, it is important to understand which context-specific SB…
View article: USING LATENT CLASS GROWTH ANALYSIS TO IDENTIFY SUBGROUPS OF OLDER ADULTS WITH SHARED TRAJECTORIES OF FRAILTY STATUS
USING LATENT CLASS GROWTH ANALYSIS TO IDENTIFY SUBGROUPS OF OLDER ADULTS WITH SHARED TRAJECTORIES OF FRAILTY STATUS Open
Background Frailty is a geriatric syndrome with significant clinical heterogeneity among older adults. Identifying groups experiencing different frailty trajectories is critical for identifying those at high risk of frailty progression and…
View article: Tech + touch: A pilot study to facilitate access to health information technology for Spanish-speaking parents
Tech + touch: A pilot study to facilitate access to health information technology for Spanish-speaking parents Open
Spanish-speaking parents express high interest in HIT. Provision of tablets may augment electronic capacity and facilitate video visits. Greater Spanish-language support is needed for Spanish-speaking parents to meaningfully use portals.
View article: Tech + touch: A pilot study to facilitate access to health information technology for Spanish-speaking parents
Tech + touch: A pilot study to facilitate access to health information technology for Spanish-speaking parents Open
View article: Community-engaged implementation of a safety bundle for pregnancy-related severe hypertension in the outpatient setting: protocol for a type 3 hybrid study with a multiple baseline design
Community-engaged implementation of a safety bundle for pregnancy-related severe hypertension in the outpatient setting: protocol for a type 3 hybrid study with a multiple baseline design Open
This study was registered with ClinicalTrials.gov as "Testing Implementation Strategies to Support Clinic Fidelity to an Outpatient Hypertension Bundle (AC3HIEVE)." Registration number NCT06002165, August 21, 2023: https://clini…
View article: mHealth Physical Activity and Patient-Reported Outcomes in Patients With Inflammatory Bowel Diseases: Cluster Analysis
mHealth Physical Activity and Patient-Reported Outcomes in Patients With Inflammatory Bowel Diseases: Cluster Analysis Open
Background Regular physical activity is associated with improved quality of life in patients with inflammatory bowel diseases (IBDs), although much of the existing research is based on self-reported data. Wearable devices provide objective…
View article: Serum Fructosamine as an Indicator of Perioperative Complications in Patients Undergoing Foot and Ankle Surgery
Serum Fructosamine as an Indicator of Perioperative Complications in Patients Undergoing Foot and Ankle Surgery Open
Background: Patients with poor glycemic control are at increased risk of postoperative complications. Hemoglobin A 1c (HbA 1c ) has traditionally been used to assess preoperative glycemic control, but with limitations. More recently, fruct…
View article: Pre‐post‐evaluation of a dementia‐specific advance care planning toolkit for Japanese primary care clinicians
Pre‐post‐evaluation of a dementia‐specific advance care planning toolkit for Japanese primary care clinicians Open
Background The population of people living with dementia (PLwD) continues to grow in Japan where advance care planning (ACP) for PLwD is relatively new. Our aim was to evaluate the feasibility and cultural acceptability of a dementia‐speci…
View article: Pre‐post‐evaluation of a dementia‐specific advance care planning toolkit for Japanese primary care clinicians
Pre‐post‐evaluation of a dementia‐specific advance care planning toolkit for Japanese primary care clinicians Open
BACKGROUND: The population of people living with dementia (PLwD) continues to grow in Japan where advance care planning (ACP) for PLwD is relatively new. Our aim was to evaluate the feasibility and cultural acceptability of a dementia-spec…
View article: Protocol for a Study Investigating Context-Specific Sedentary Behaviors and Cardiometabolic Health in College-Based Young Adults (CONTEXT-SB)
Protocol for a Study Investigating Context-Specific Sedentary Behaviors and Cardiometabolic Health in College-Based Young Adults (CONTEXT-SB) Open
Background Sedentary behavior (SB) is detrimental to cardiometabolic disease (CMD) risk, which can begin in young adulthood. To devise effective SB-CMD interventions in young adults, it is important to understand which context-specific sed…
View article: The utility of home blood pressure load in predicting average self-measured blood pressure
The utility of home blood pressure load in predicting average self-measured blood pressure Open
Objectives: Average values for self-measured blood pressure (SMBP) more accurately reflect a patient's risk of cardiovascular disease than do office measurements. Oftentimes, however, patients provide lists of individual home blood pressur…
View article: Microheterogeneity of Transmission Shapes Submicroscopic Malaria Carriage in Coastal Tanzania
Microheterogeneity of Transmission Shapes Submicroscopic Malaria Carriage in Coastal Tanzania Open
Background Asymptomatic carriage of malaria parasites persists even as malaria transmission declines. Low-density infections are often submicroscopic, not detected with rapid diagnostic tests (RDTs) or microscopy but detectable by polymera…