Fengguang Zhai
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View article: Author Correction: The role of IGF2BP3/SPOP/c-Myc loop in paclitaxel resistance of endometrial cancer
Author Correction: The role of IGF2BP3/SPOP/c-Myc loop in paclitaxel resistance of endometrial cancer Open
View article: LMNB2-mediated high PD-L1 transcription triggers the immune escape of hepatocellular carcinoma
LMNB2-mediated high PD-L1 transcription triggers the immune escape of hepatocellular carcinoma Open
View article: The role of IGF2BP3/SPOP/c-Myc loop in paclitaxel resistance of endometrial cancer
The role of IGF2BP3/SPOP/c-Myc loop in paclitaxel resistance of endometrial cancer Open
Paclitaxel combination therapy is the main chemotherapy regimen for endometrial cancer (EC); however, subsequent drug resistance is a bottleneck limiting its widespread clinical application. We found that human insulin-like growth factor 2…
View article: Analysis and identification of PTBP2 as an oncogene in hepatocellular carcinoma
Analysis and identification of PTBP2 as an oncogene in hepatocellular carcinoma Open
Our study demonstrated that HCC tissues exhibited increased levels of PTBP2 expression compared to normal liver tissues. Elevated PTBP2 expression has been identified as closely linked to low survival in patients with HCC and could be a cl…
View article: Advances in the understanding of nuclear pore complexes in human diseases
Advances in the understanding of nuclear pore complexes in human diseases Open
Background Nuclear pore complexes (NPCs) are sophisticated and dynamic protein structures that straddle the nuclear envelope and act as gatekeepers for transporting molecules between the nucleus and the cytoplasm. NPCs comprise up to 30 di…
View article: Exploring the Role of Ubiquitin-Proteasome System in the Pathogenesis of Parkinson’s Disease
Exploring the Role of Ubiquitin-Proteasome System in the Pathogenesis of Parkinson’s Disease Open
Parkinson’s disease (PD) is a prevalent neurodegenerative disorder among the elderly population. The pathogenesis of PD encompasses genetic alterations, environmental factors, and age-related neurodegenerative processes. Numerous studies h…
View article: NOLC1 was identified as a tumor suppressor gene in thyroid cancer and correlated with prognosis by bioinformatics
NOLC1 was identified as a tumor suppressor gene in thyroid cancer and correlated with prognosis by bioinformatics Open
Thyroid cancer (THCA) is the most common endocrine malignancy, mainly affecting women's unilateral glandular lobes. However, for relapsed and distant metastasis of THCA patients, the existing early diagnosis and treatment methods were stil…
View article: Roles of NOLC1 in cancers and viral infection
Roles of NOLC1 in cancers and viral infection Open
View article: Regulation of apoptosis by ubiquitination in liver cancer.
Regulation of apoptosis by ubiquitination in liver cancer. Open
Apoptosis is a programmed cell death process critical to cell development and tissue homeostasis in multicellular organisms. Defective apoptosis is a crucial step in the malignant transformation of cells, including hepatocellular carcinoma…
View article: The E3 Ligases in Cervical Cancer and Endometrial Cancer
The E3 Ligases in Cervical Cancer and Endometrial Cancer Open
Endometrial (EC) and cervical (CC) cancers are the most prevalent malignancies of the female reproductive system. There is a global trend towards increasing incidence and mortality, with a decreasing age trend. E3 ligases label substrates …