Fengjiang Wei
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View article: Integrated traditional Chinese and western nursing care of an elderly patient with toxic epidermal necrolysis complicated by malignant tumors of the prostate
Integrated traditional Chinese and western nursing care of an elderly patient with toxic epidermal necrolysis complicated by malignant tumors of the prostate Open
To summarize the experience of integrated traditional Chinese and western nursing care of an elderly patient with toxic epidermal necrolysis complicated by malignant tumors of the prostate. The patient was treated using a combination of tr…
Additional file 1 of Histone deacetylase inhibitors VPA and WT161 ameliorate the pathological features and cognitive impairments of the APP/PS1 Alzheimer’s disease mouse model by regulating the expression of APP secretases Open
Additional file 1: Fig. S1. CCK-8 detects drug toxicity in N2a-APPswe. a Cytotoxic effect of VPA on N2a-APPswe. b Cytotoxic effects of WT161 on N2a-APPswe. Fig. S2. Effect of VPA and WT161 on the expression of histone deacetylases. a Weste…
An early prediction model for type 2 diabetes mellitus based on genetic variants and nongenetic risk factors in a Han Chinese cohort Open
Aims We aimed to construct a prediction model of type 2 diabetes mellitus (T2DM) in a Han Chinese cohort using a genetic risk score (GRS) and a nongenetic risk score (NGRS). Methods A total of 297 Han Chinese subjects who were free from ty…
Histone deacetylase inhibitors VPA and WT161 ameliorate the pathological features and cognitive impairments of the Alzheimer's disease mouse model by regulating the expression of App secretases Open
Background Alzheimer's disease (AD) is a degenerative neurological disorder. Recent studies have indicated that histone deacetylases (HDACs) are among the most prominent epigenetic therapy targets and that HDAC inhibitors have therapeutic …
<span> PGF <sub>2α</sub> </span> facilitates pathological retinal angiogenesis by modulating endothelial <span>FOS</span> ‐driven <span>ELR</span> <sup>+</sup> <span>CXC</span> chemokine expression Open
The pathological retinal angiogenesis often causes blindness. Current anti-angiogenic therapy for proliferative retinopathy targets the vascular endothelial growth factor (VEGF), but many patients do not radically benefit from this therapy…
An Early Prediction Model for Chronic Kidney Disease Open
Background: Identifying individuals predisposed to chronic kidney disease (CKD) is crucial for intervention and treatment, however, risk equations were relatively rare among the middle-aged and elderly in China.Methods: Eventually, 116 CKD…
Association of hypertension and hypertriglyceridemia on incident hyperuricemia: An 8-year prospective cohort study Open
Background Hypertension and high triglyceride are two of the most important risk factors for hyperuricemia. Epidemiological records show that hypertension and dyslipidemia often coexist and may significantly increase the risk of target org…
Association of Hypertension and Hypertriglyceridemia on Incident Hyperuricemia: An 8-year Prospective Cohort Study Open
BackgroundHypertension and high triglyceride are two of the most important risk factors for hyperuricemia. Epidemiological records show that hypertension and dyslipidemia often coexist and may significantly increase the risk of target orga…
View article: Higher Serum Uric Acid Level Predicts Non-alcoholic Fatty Liver Disease: A 4-Year Prospective Cohort Study
Higher Serum Uric Acid Level Predicts Non-alcoholic Fatty Liver Disease: A 4-Year Prospective Cohort Study Open
Background: Non-alcoholic fatty liver disease (NAFLD) has become a serious disease affecting people's health in the world. This article studies the causal relationship between NAFLD and serum uric acid (SUA) levels. Methods: During the 4 y…
Triglyceride is an independent predictor of type 2 diabetes among middle-aged and older adults: a prospective study with 8-year follow-ups in two cohorts Open
Background Although there is abundant evidence indicating the connection between triglyceride and type 2 diabetes mellitus (T2DM), few reports or cohort studies confirm that high TG concentration may predict the incidence of T2DM independe…