Fengwei Wang
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View article: An integrated transcriptomic analysis of brain aging and strategies for healthy aging
An integrated transcriptomic analysis of brain aging and strategies for healthy aging Open
Background It is been noted that the expression levels of numerous genes undergo changes as individuals age, and aging stands as a primary factor contributing to age-related diseases. Nevertheless, it remains uncertain whether there are co…
View article: The Potential Therapeutic Targets of Anlotinib in Osteosarcoma: Characterization Based on Patient‐Derived Xenografts and Next‐Generation Sequencing
The Potential Therapeutic Targets of Anlotinib in Osteosarcoma: Characterization Based on Patient‐Derived Xenografts and Next‐Generation Sequencing Open
Background The aim of this study was to analyze the potential therapeutic targets of anlotinib using the patient‐derived xenografts (PDX) and evaluate the efficacy of the combination of chemotherapy and anlotinib in osteosarcoma patients b…
View article: METTL3 confers oxaliplatin resistance through the activation of G6PD-enhanced pentose phosphate pathway in hepatocellular carcinoma
METTL3 confers oxaliplatin resistance through the activation of G6PD-enhanced pentose phosphate pathway in hepatocellular carcinoma Open
View article: An efficient improved singular spectrum analysis for processing GNSS position time series with missing data
An efficient improved singular spectrum analysis for processing GNSS position time series with missing data Open
SUMMARY The improved SSA (ISSA) method is widely recognized for directly extracting signals from gappy time-series without requiring prior interpolation. However, it is rather time consuming, particularly for long time-series with large wi…
View article: An improved Gaussian process for filling the missing data in GNSS position time series considering the influence of adjacent stations
An improved Gaussian process for filling the missing data in GNSS position time series considering the influence of adjacent stations Open
View article: Practical and privacy-preserving geo-social-based POI recommendation
Practical and privacy-preserving geo-social-based POI recommendation Open
With the rapid development of location-based services and online social networks, POI recommendation services considering geographic and social factors have received extensive attention. Meanwhile, the vigorous development of cloud computi…
View article: YTHDC1 delays cellular senescence and pulmonary fibrosis by activating ATR in an m6A-independent manner
YTHDC1 delays cellular senescence and pulmonary fibrosis by activating ATR in an m6A-independent manner Open
Accumulation of DNA damage in the lung induces cellular senescence and promotes age-related diseases such as idiopathic pulmonary fibrosis (IPF). Hence, understanding the mechanistic regulation of DNA damage repair is important for anti-ag…
View article: KRAS status predicted by pretreatment MRI radiomics was associated with lung metastasis in locally advanced rectal cancer patients
KRAS status predicted by pretreatment MRI radiomics was associated with lung metastasis in locally advanced rectal cancer patients Open
Background Mutated KRAS may indicate an invasive nature and predict prognosis in locally advanced rectal cancer (LARC). We aimed to establish a radiomic model using pretreatment T2W MRIs to predict KRAS status and explore the association b…
View article: MRI-based radiomics to predict neoadjuvant chemoradiotherapy outcomes in locally advanced rectal cancer: A multicenter study
MRI-based radiomics to predict neoadjuvant chemoradiotherapy outcomes in locally advanced rectal cancer: A multicenter study Open
View article: Security and Privacy Threats to Federated Learning: Issues, Methods, and Challenges
Security and Privacy Threats to Federated Learning: Issues, Methods, and Challenges Open
Federated learning (FL) has nourished a promising method for data silos, which enables multiple participants to construct a joint model collaboratively without centralizing data. The security and privacy considerations of FL are focused on…
View article: MRI radiomics independent of clinical baseline characteristics and neoadjuvant treatment modalities predicts response to neoadjuvant therapy in rectal cancer
MRI radiomics independent of clinical baseline characteristics and neoadjuvant treatment modalities predicts response to neoadjuvant therapy in rectal cancer Open
View article: Author response for "Cyr61 from adipose‐derived stem cells promotes colorectal cancer metastasis and vasculogenic mimicry formation via integrin α V β 5"
Author response for "Cyr61 from adipose‐derived stem cells promotes colorectal cancer metastasis and vasculogenic mimicry formation via integrin α V β 5" Open
Adipose-derived stem cells (ADSCs) play a vital role in colorectal cancer (CRC) progression, but the mechanism remains largely unknown. Herein, we found that ADSCs isolated from CRC patients produced more cysteine-rich 61 (Cyr61) than thos…
View article: The complete chloroplast genome sequence of <i>Actinidia arguta</i> var<i>. giraldii</i>
The complete chloroplast genome sequence of <i>Actinidia arguta</i> var<i>. giraldii</i> Open
The complete chloroplast (cp) genome sequence of Actinidia arguta var. giraldii (Diels) Vorosch. was assembled and characterized by Illumina pair-end sequencing date. The complete plastid genome was 156,729 bp in length, cont…
View article: Tumor-intrinsic CD47 signal regulates glycolysis and promotes colorectal cancer cell growth and metastasis
Tumor-intrinsic CD47 signal regulates glycolysis and promotes colorectal cancer cell growth and metastasis Open
Rationale: CD47 plays a vital role in the immune escape of tumor cells, but its role in regulating immune-unrelated biological processes such as proliferation and metastasis remains unclear. We seek to explore the immune-independent…
View article: Exosomes from mesenchymal stromal cells reduce murine colonic inflammation via a macrophage-dependent mechanism
Exosomes from mesenchymal stromal cells reduce murine colonic inflammation via a macrophage-dependent mechanism Open
Conventional treatments for inflammatory bowel disease (IBD) have multiple potential side effects. Therefore, alternative treatments are desperately needed. This work demonstrated that systemic administration of exosomes from human bone ma…
View article: Privacy-Preserving Collaborative Model Learning Scheme for E-Healthcare
Privacy-Preserving Collaborative Model Learning Scheme for E-Healthcare Open
With the advances of data mining and the pervasiveness of cloud computing, online medical diagnosis service has been extensively applied in e-heathcare field, and brought great conveniences to people's life. However, due to the insufficien…
View article: Multistage virtual screening and identification of novel HIV-1 protease inhibitors by integrating SVM, shape, pharmacophore and docking methods
Multistage virtual screening and identification of novel HIV-1 protease inhibitors by integrating SVM, shape, pharmacophore and docking methods Open
View article: Extraction Salidroside with Aqueous Two-phase System
Extraction Salidroside with Aqueous Two-phase System Open
Extraction salidroside with the aqueous two-phase system.Through several single-factor tests: Polyethylene glycol (PEG) molecular weight, the mass fraction of PEG, the kinds of salt, the salt mass fraction and ionic strength.Get changes Sa…
View article: Study on Distribution Behavior in Aqueous Two-phase System about Four Kinds of Alkaloids in Coptis Chinensis
Study on Distribution Behavior in Aqueous Two-phase System about Four Kinds of Alkaloids in Coptis Chinensis Open
Using aqueous two-phase to extract alkaloids in coptis chinensis.By changing the aqueous two-phase systems (molecular weight and concentration of polyethylene glycol (PEG), kinds and concentration of salt), and researched the distribution …