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View article: Astaxanthin Prevents Oxidative Damage and Cell Apoptosis Under Oxidative Stress Involving the Restoration of Mitochondrial Function
Astaxanthin Prevents Oxidative Damage and Cell Apoptosis Under Oxidative Stress Involving the Restoration of Mitochondrial Function Open
Oxidative stress (OS) is one of the factors that result in cell damage and the development of neurological diseases such as Alzheimer's disease (AD). Astaxanthin (ASTA), a natural compound known for its potent antioxidant properties, shows…
View article: Roles of TREM2 in the Pathological Mechanism and the Therapeutic Strategies of Alzheimer's Disease
Roles of TREM2 in the Pathological Mechanism and the Therapeutic Strategies of Alzheimer's Disease Open
Alzheimer's disease (AD) is an age-related degenerative disease, which is characteristic by the deposition of senile plaques (SP) outside the cells, the neurofibrillary tangles (NFTs) inside the neurons, and the loss of synapse and neurons…
View article: Design Strategies and Precautions for Using Vaccinia Virus in Tumor Virotherapy
Design Strategies and Precautions for Using Vaccinia Virus in Tumor Virotherapy Open
Oncolytic virotherapy has emerged as a novel form of cancer immunotherapy. Oncolytic viruses (OVs) can directly infect and lyse the tumor cells, and modulate the beneficial immune microenvironment. Vaccinia virus (VACV) is a promising onco…
View article: Protective Effect of Zeaxanthin against Tunicamycin-induced Cell Damage in SH-SY5Y Cell
Protective Effect of Zeaxanthin against Tunicamycin-induced Cell Damage in SH-SY5Y Cell Open
Endoplasmic reticulum (ER) stress and the resulting neuronal cell damage have been implicated in the development and progression of Alzheimer's disease. Tunicamycin (TM) induces ER stress in vitro, and the protective effects of the caroten…
View article: Naturally Occurring Cinnamic Acid Sugar Ester Derivatives
Naturally Occurring Cinnamic Acid Sugar Ester Derivatives Open
Cinnamic acid sugar ester derivatives (CASEDs) are a class of natural product with one or several phenylacrylic moieties linked with the non-anomeric carbon of a glycosyl skeleton part through ester bonds. Their notable anti-depressant and…