Fengzhen Cui
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View article: Role of c-Myc activating the transcription of PD-L1 in immune escape during benzene-induced malignant transformation of human lymphoblasts
Role of c-Myc activating the transcription of PD-L1 in immune escape during benzene-induced malignant transformation of human lymphoblasts Open
Benzene is a widely used industrial raw material. Benzene and its metabolite hydroquinone are believed to be related to the occurrence of benzene-related leukemia. Epidemiological studies have revealed the link between benzene exposure and…
View article: Maternal phthalates exposure promotes neural stem cell differentiation into phagocytic astrocytes and synapse engulfment via IRE1α/XBP1s pathway
Maternal phthalates exposure promotes neural stem cell differentiation into phagocytic astrocytes and synapse engulfment via IRE1α/XBP1s pathway Open
Humans are widely exposed to phthalates, a common chemical plasticizer. Previous cohort studies have revealed that maternal exposure to monobutyl phthalate (MBP), a key metabolite of phthalates, is associated with neurodevelopmental defect…
View article: A simple polydopamine‐based platform for engineering extracellular vesicles with brain‐targeting peptide and imaging probes to improve stroke outcome
A simple polydopamine‐based platform for engineering extracellular vesicles with brain‐targeting peptide and imaging probes to improve stroke outcome Open
Extracellular vesicles (EVs) have shown great potential for treating various diseases. Translating EVs‐based therapy from bench to bedside remains challenging due to inefficient delivery of EVs to the injured area and lack of techniques to…
View article: Environmental monobutyl phthalate exposure promotes liver cancer via reprogrammed cholesterol metabolism and activation of the IRE1α-XBP1s pathway
Environmental monobutyl phthalate exposure promotes liver cancer via reprogrammed cholesterol metabolism and activation of the IRE1α-XBP1s pathway Open
Humans are widely exposed to phthalates, a major chemical plasticizer that accumulates in the liver. However, little is known about the impact of chronic phthalate exposure on liver cancer development. In this study, we applied a long-term…
View article: Interaction Between the PERK/ATF4 Branch of the Endoplasmic Reticulum Stress and Mitochondrial One-Carbon Metabolism Regulates Neuronal Survival After Intracerebral Hemorrhage
Interaction Between the PERK/ATF4 Branch of the Endoplasmic Reticulum Stress and Mitochondrial One-Carbon Metabolism Regulates Neuronal Survival After Intracerebral Hemorrhage Open
Recent investigations have revealed that oxidative stress can lead to neuronal damage and disrupt mitochondrial and endoplasmic reticulum functions after intracerebral hemorrhage (ICH). However, there is limited evidence elucidating their …
View article: Integrated analysis of single-cell and bulk transcriptomics develops a robust neuroendocrine cell-intrinsic signature to predict prostate cancer progression
Integrated analysis of single-cell and bulk transcriptomics develops a robust neuroendocrine cell-intrinsic signature to predict prostate cancer progression Open
Neuroendocrine prostate cancer (NEPC) typically implies severe lethality and limited treatment options. The precise identification of NEPC cells holds paramount significance for both research and clinical applications, yet valid NEPC bioma…
View article: Mapping of Soil Liquefaction Associated with the 2021 Mw 7.4 Maduo (Madoi) Earthquake Based on the UAV Photogrammetry Technology
Mapping of Soil Liquefaction Associated with the 2021 Mw 7.4 Maduo (Madoi) Earthquake Based on the UAV Photogrammetry Technology Open
The 2021 Mw 7.4 Maduo (Madoi) earthquake that struck the northern Tibetan Plateau resulted in widespread coseismic deformation features, such as surface ruptures and soil liquefaction. By utilizing the unmanned aerial vehicle (UAV) photogr…
View article: Association of exposure to per- and polyfluoroalkyl substances with hemoglobin and hematocrit during pregnancy
Association of exposure to per- and polyfluoroalkyl substances with hemoglobin and hematocrit during pregnancy Open
Maternal PFASs exposure was positive with serum Hb and HCT. Moreover, maternal iron supplementation may play a modifying effect in influencing the relationship between PFASs and HCT and Hb.
View article: A novel prognostic signature in osteosarcoma characterised from the perspective of unfolded protein response
A novel prognostic signature in osteosarcoma characterised from the perspective of unfolded protein response Open
Osteosarcoma (OS) is the most common primary malignant tumour of bone with variable molecular biology and prognosis. This makes better patient stratification and precision treatment an urgent clinical need.1 Activation of the unfolded prot…
View article: Maternal Benzophenone Exposure Impairs Hippocampus Development and Cognitive Function in Mouse Offspring (Adv. Sci. 23/2021)
Maternal Benzophenone Exposure Impairs Hippocampus Development and Cognitive Function in Mouse Offspring (Adv. Sci. 23/2021) Open
Maternal Benzophenone Exposure In article number 2102686 by Shunqing Xu, Yaohui Tang, Xia Sheng, and co‐workers, it is reported that maternal exposure to benzophenone and its major metabolite 4‐hydroxybenzophenone during pregnancy causes e…
View article: Maternal Benzophenone Exposure Impairs Hippocampus Development and Cognitive Function in Mouse Offspring
Maternal Benzophenone Exposure Impairs Hippocampus Development and Cognitive Function in Mouse Offspring Open
Benzophenones are widely supplemented in personal care products, but little is known about its neurodevelopmental toxicity. The previous epidemiological study discovered a negative correlation between maternal exposure to a benzophenone me…
View article: Characterization of Molecular Subtypes in Head and Neck Squamous Cell Carcinoma With Distinct Prognosis and Treatment Responsiveness
Characterization of Molecular Subtypes in Head and Neck Squamous Cell Carcinoma With Distinct Prognosis and Treatment Responsiveness Open
Head and neck squamous cell carcinoma (HNSCC) is one of the most aggressive malignancies with complex phenotypic, etiological, biological, and clinical heterogeneities. Previous studies have proposed different clinically relevant subtypes …