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View article: Clinical Characteristics, Treatment Approaches, and Survival Predictors in Adult Acute Myeloid Leukemia: Interim Results from the Turkish Society of Hematology AML Registry
Clinical Characteristics, Treatment Approaches, and Survival Predictors in Adult Acute Myeloid Leukemia: Interim Results from the Turkish Society of Hematology AML Registry Open
Background: Acute myeloid leukemia (AML) is an aggressive and biologically diverse hematologic cancer that disproportionately affects older individuals. Despite advances in molecular profiling and therapy, long-term outcomes remain unsatis…
Allogeneic Hematopoietic Stem Cell Transplantation in Relapsed Refractory Multiple Myeloma Open
Objectives: Allo-Hematopoietic Stem Cell Transplantation (HSCT) offers a curative option for relapsed and refractory multiple myeloma in younger aged and fit patients with high-risk cytogenetic properties. Material and Methods: This study …
HARMONIZATION OF TREATMENT APPROACHES: DRAWING INSPIRATION FROM PEDIATRIC TREATMENTS IN ADULT ACUTE LYMPHOBLASTIC LEUKEMIA THERAPY Open
Age, genetic characteristics, comorbidities, and minimal residual disease determine prognosis in patients with Acute Lymphoblastic Leukemia (ALL). Advanced age, the presence of adverse genetic markers and reduced treatment intensity typica…
INTERVENTIONAL PROCEDURE IN HEMOPHILIA A PATIENT WITH EXTENDED HALF-LIFE FACTOR THERAPY- CIRCUMCISION- CASE REPORT Open
Case Report: Hemophilia A is a hereditary bleeding disorder due to factor VIII deficiency. With the advances in the treatment of hemophilia in recent years, the average life expectancy of patients has reached the healthy population. Along …
Prognostic Value of Hyperlactatemia and Lactate Clearance in Septic Patients With Hematological Malignancies Open
Background: The coexistence of sepsis and hematological malignancies increases patient vulnerability, revealing the need for precise prognostic markers. This study explores the prognostic significance of lactate levels and clearance in sep…
EFFECT OF HEREDITARY THROMBOPHILIA ON ARTERIAL THROMBOSIS Open
Objective: Screening for hereditary thrombophilia is recommended for venous thrombosis, but there is conflicting information about the causal relation with arterial thrombosis. In this study, in order to clarify these conflicting results a…
Allogeneic Hematopoietic Stem Cell Transplantation in Relapsed Refractory Multiple Myeloma Open
Objectives Allo-Hematopoietic Stem Cell Transplantation (HSCT) offers a curative option for relapsed and refractory multiple myeloma in younger aged and fit patients with high-risk cytogenetic properties. Material and Methods This study re…
Real life data comparing weekly VCD and twice weekly VCD protocols in newly diagnosed multiple myeloma patients Open
Background This study aimed to evaluate the efficacy and side effects of bortezomib, cyclophosphamide, and dexamethasone (VCD) treatment, which is frequently preferred in primary care in patients with multiple myeloma in our country, with …
Comparison of low dose cytosine arabinoside, azacitidine and azacitidine venetoclax combination treatment as remission induction in elderly acute myeloid leukemia patients Open
Aims: Low-intensity therapies are widely preferred in the treatment of advanced age, fragile acute myeloid leukemia (AML) patients. In this study, we aimed to compare hematological recovery rates after first cycle chemotherapy and overall …
Long-term Results of Imatinib Discontinuation in Patients with Chronic-phase Chronic Myeloid Leukemia: A National Multicenter Prospective Study Open
Objective: The discovery of imatinib was a milestone for chronic myeloid leukemia (CML). As the life expectancy of CML patients has approached that of the general population, research has shifted towards improving quality of life and econo…
View article: Prospective Real-World Outcomes of Acute Myeloid Leukemia
Prospective Real-World Outcomes of Acute Myeloid Leukemia Open
Background: It is evident that treatment outcomes improve with the clinical studies, in this study we aimed to investigate the demographics and treatment modalities of the acute myeloid leukemia (AML) patients in a large population-based c…
Long-term Results of Imatinib Discontinuation in Patients with Chronic Phase Chronic Myeloid Leukemia: National Multicenter Prospective Study Open
Tyrosine kinase inhibitor discontinuation with close molecular monitoring is a safe option and provides important national economic benefits for chronic phase CML patients. This approach should be considered for all eligible patients. This…
Salvage Autologous Hematopoietic Stem Cell Transplantation Versus Chemoimmunotherapy in Relapsed Multiple Myeloma Patients After First Transplantation; Single Center Data Open
Objectives: Multiple myeloma (MM) is an uncurable disease and standard therapy for relapsed MM is still not clear.We aimed to compare salvage treatments for relapsed refractory MM. Materials and Methods:Sixty patients who relapsed after fi…
Darbepoietin Alfa Treatment in Myelodysplastic Syndrome: Single Center Data Open
Amaç: Düşük riskli miyelodisplastik sendrom (MDS) hastalarında eritropoezi uyarıcı ilaçların özellikle eritropoetin düzeyi 500 U/L altındaki hastalarda transfüzyon bağımsızlığını sağlamada yararı gösterilmiştir.Çalışmada merkezimizde MDS i…
Perioperative Management of Patients with Rare Congenital Factor Deficiency Open
Objectives: Fibrinogen, prothrombin, factor V, VII, X, XI, XIII and V+VIII deficiencies are defined as rare congenital factor deficiencies (RCD).Due to small number of patients and lack of data, perioperative management can be challeging.W…
Opioid Administration for Mucositis-related-Pain Using Patient Controlled Analgesia (PCA) Method is Associated with the Development of Early Posttransplant Complications Open
Introduction: Mucositis is one of the major complications of allogeneic hematopoietic stem cell transplantation with myeloablative conditioning.Several measures have been developed to improve pain palliation and quality of life in transpla…
A Giant Mass in the Eyelid: Peripheral T-Cell Lymphoma, Not Otherwise Specified Open
Purpose: To report a case with an unusual giant mass in the eyelid which was diagnosed as peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS). Methods: A 40-year-old woman was referred with a 1-year history of rapidly and consta…
COVID-19 Disease in Patients with Hematological Disease-Single Center Data Open
Objectives: Coronavirus disease-2019 (COVID-19) is a pandemic that has been the main issue of the healthcare since December 2019.There are difficulties in treatment and follow-up for hematology patients.In this study, we aimed to share dat…
View article: Standart Prophylactic Granulocyte Colony Stimulating Factor Usage As A Part Of Autologous Stem Cell Transplantation Procedure
Standart Prophylactic Granulocyte Colony Stimulating Factor Usage As A Part Of Autologous Stem Cell Transplantation Procedure Open
Introduction: One of the major causes of morbidity and mortality of autologous hematopoietic stem cell transplantation (ASCT) is infections during prolonged neutropenia.In this study, we aimed to investigate the effect of prophylactic G-CS…
Hypofibrinogenemia caused by tigecycline use in a patient with acute cholecystitis: a case report and review of the literature Open
Tigecycline is the first member of glicylcycline class of antibiotics, which has a broad spectrum of action. In previous reports, coagulopathy and hypofibrinogenemia caused by tigecycline use was described. We aimed to present a case of hy…
View article: Does Immunohistochemically CD5 Positivity Matter In Diffuse Large B-Cell Lymphoma Patients? Turkish Multicenter Study
Does Immunohistochemically CD5 Positivity Matter In Diffuse Large B-Cell Lymphoma Patients? Turkish Multicenter Study Open
Background: Diffuse large B-cell lymphoma (DLBCL) is the most common sub-type of Non-Hodgkin lymphomas (NHL) and it is a very heterogeneous group of diseases. CD5 positivity is profound in a substantial patient population in DLBCL. In this…
View article: Clinical Characteristics and Outcomes of COVID-19 in Turkish Patients with Hematological Malignancies
Clinical Characteristics and Outcomes of COVID-19 in Turkish Patients with Hematological Malignancies Open
Patients with hematological malignancy infected with SARS-CoV-2 have an increased risk of severe disease and mortality.
Massive Platelet Clumping on Peripheral Blood Smear and Pseudothrombocytopenia in a Patient with COVID-19 Open
FIG. 1. Pseudothrombocytopenia with massive platelet clumping in a patient with COVID 19.
View article: Infections in hematopoietic stem cell transplant patients admitted to Hematology intensive care unit: a single-center study
Infections in hematopoietic stem cell transplant patients admitted to Hematology intensive care unit: a single-center study Open
It was concluded that early or late post-HSCT infections and related complications (sepsis, organ failure, etc.) constituted a major part of the reasons for ICU admission, ICU mortality and ICU morbidities.
Comparison of Post-Remission Strategies in Acute Myeloid Leukemia: Autologous Hematopoietic Stem Cell Transplantation versus Consolidation Chemotherapy Open
Autologous Hematopoietic Stem Cell Transplantation (auto-HSCT) has become a therapeutic option for first-line consolidation in Acute Myeloid Leukemia (AML) patients with favorable and intermediate risk features. A total of 101 AML patients…