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View article: Carbamate insecticide bendiocarb induces complex embryotoxic effects, including morphological, behavioral, transcriptional, and immunological alterations in zebrafish
Carbamate insecticide bendiocarb induces complex embryotoxic effects, including morphological, behavioral, transcriptional, and immunological alterations in zebrafish Open
The emergence and spread of vector-borne diseases necessitate the increased use of insecticides, such as carbamates, raising concerns about their potential toxicological risks to non-target organisms, including humans. Bendiocarb, frequent…
View article: New Light on an Old Story: Lymphocystis Disease in Copperband Butterflyfish (Chelmon rostratus) and Orbicular Batfish (Platax orbicularis)
New Light on an Old Story: Lymphocystis Disease in Copperband Butterflyfish (Chelmon rostratus) and Orbicular Batfish (Platax orbicularis) Open
Although the clinical course and pathogenesis of lymphocystis disease virus (LCDV) infection have been extensively described in freshwater and seawater environments, lymphocystis disease has not been studied in the copperband butterflyfish…
View article: First record of <i>Argulus japonicus</i> infestation on <i>Cyprinus carpio</i> in Hungary, and the first description of <i>Argulus japonicus</i> subsp. <i>europaeus</i> subsp. nov. Keve, 2025
First record of <i>Argulus japonicus</i> infestation on <i>Cyprinus carpio</i> in Hungary, and the first description of <i>Argulus japonicus</i> subsp. <i>europaeus</i> subsp. nov. Keve, 2025 Open
Species belonging to the genus Argulus are globally distributed fish parasites. Their veterinary significance primarily lies in their disruptive presence and their role as mechanical vectors. Although Argulus japonicus Thiele, 1900 is a wi…
View article: Toxicity of Low-Level Multiple-Mycotoxin Mixture in Nile Tilapia (Oreochromis niloticus) Is Prevented with Organically Modified Clinoptilolite Feed Additive
Toxicity of Low-Level Multiple-Mycotoxin Mixture in Nile Tilapia (Oreochromis niloticus) Is Prevented with Organically Modified Clinoptilolite Feed Additive Open
Organically modified clinoptilolite (member of the zeolite family of minerals; MinazelPlus®) feed additive, with an average weight of 30 ± 2 g, was used to prevent mycotoxicosis in Nile tilapia (Oreochromis niloticus) through its supplemen…
View article: First Experimental Application of DNA-Layered Salmonid Alphavirus-Based Replicon Vaccine in Non-Salmonid Fish: Induced Early Semi-Specific Protection against Spring Viraemia of Carp Virus (SVCV) in Common Carp (Cyprinus carpio)
First Experimental Application of DNA-Layered Salmonid Alphavirus-Based Replicon Vaccine in Non-Salmonid Fish: Induced Early Semi-Specific Protection against Spring Viraemia of Carp Virus (SVCV) in Common Carp (Cyprinus carpio) Open
Our study demonstrates the first application of the salmonid alphavirus-based replicon vector system (pSAV) as a DNA vaccine in a non-salmonid fish species, in common carp (Cyprinus carpio) against spring viraemia of carp virus (SVCV). SAV…
View article: Discovery and Characterization of RGH-122, a Potent, Selective, and Orally Bioavailable V1a Receptor Antagonist
Discovery and Characterization of RGH-122, a Potent, Selective, and Orally Bioavailable V1a Receptor Antagonist Open
The V1a receptor is a major contributor in mediating the social and emotional effects of arginine-vasopressin (AVP); therefore it represents a promising target in the treatment of several neuropsychiatric conditions. The aim of this resear…
View article: New Insights into the Morphological Diversity of Saprolegnia parasitica (Oomycota) Strains under In Vitro Culture Conditions
New Insights into the Morphological Diversity of Saprolegnia parasitica (Oomycota) Strains under In Vitro Culture Conditions Open
Saprolegnia parasitica Coker, 1923 is a primary fish pathogen and one of the most common water molds in freshwater ecosystems. In our study, nineteen strains of S. parasitica were isolated, identified, and characterized using morphological…
View article: Herbivorous Juvenile Grass Carp (Ctenopharyngodon idella) Fed with Genetically Modified MON 810 and DAS-59122 Maize Varieties Containing Cry Toxins: Intestinal Histological, Developmental, and Immunological Investigations
Herbivorous Juvenile Grass Carp (Ctenopharyngodon idella) Fed with Genetically Modified MON 810 and DAS-59122 Maize Varieties Containing Cry Toxins: Intestinal Histological, Developmental, and Immunological Investigations Open
Feeding experiments with juvenile grass carp (Ctenopharyngodon idella) fed with genetically modified maize MON 810 or DAS-59122 dried leaf biomass were carried out with 1-, 3- and 6-month exposures. Dosages of 3–7 μg/fish/day Cry1Ab or 18-…
View article: Synthesis and Characterization of New V<sub>1A</sub> Antagonist Compounds: The Separation of Four Atropisomeric Stereoisomers
Synthesis and Characterization of New V<sub>1A</sub> Antagonist Compounds: The Separation of Four Atropisomeric Stereoisomers Open
A new class of selective vasopressin receptor 1A (V1A) antagonists was identified, where "methyl-scan" was performed around the benzene ring of the 5-hydroxy-triazolobenzazepine core. This led to the synthesis of two 10-methyl derivatives,…
View article: Intussusception caused by intestinal neoplasia in mature rainbow trout (<i>Oncorhynchus mykiss</i>, Walbaum 1792)
Intussusception caused by intestinal neoplasia in mature rainbow trout (<i>Oncorhynchus mykiss</i>, Walbaum 1792) Open
The aquaculture industry is growing and includes the farming and breeding of more than 580 aquatic species worldwide. The rainbow trout ( Oncorhynchus mykiss , Walbaum 1792) is the most commonly bred trout species in Hungary. As broodfish …
View article: Kisspeptin Neurons in the Infundibular Nucleus of Ovariectomized Cats and Dogs Exhibit Unique Anatomical and Neurochemical Characteristics
Kisspeptin Neurons in the Infundibular Nucleus of Ovariectomized Cats and Dogs Exhibit Unique Anatomical and Neurochemical Characteristics Open
Neurons co-synthesizing kisspeptin (KP), neurokinin B (NKB), and dynorphin (“KNDy neurons”) in the hypothalamic arcuate/infundibular nucleus (INF) form a crucial component of the gonadotropin-releasing hormone (GnRH)/luteinizing hormone (L…
View article: Family aggregation analysis shows a possible heritable background of equine grass sickness (dysautonomia) in a Hungarian stud population
Family aggregation analysis shows a possible heritable background of equine grass sickness (dysautonomia) in a Hungarian stud population Open
Equine grass sickness (also known as dysautonomia) is a life-threatening polyneuropathic disease affecting horses with approx. 80% mortality. Since its first description over a century ago, several factors, such as the phenotype, intestina…
View article: Detection of cyprinid herpesvirus 1 (CyHV-1) in barbel (Barbus barbus): First molecular evidence for the presence of CyHV-1 in fish other than carp (Cyprinus carpio)
Detection of cyprinid herpesvirus 1 (CyHV-1) in barbel (Barbus barbus): First molecular evidence for the presence of CyHV-1 in fish other than carp (Cyprinus carpio) Open
Two adult barbels ( Barbus barbus ) with visible skin tumours were subjected to histopathological and molecular examinations. The fish were caught in the River Danube near Budapest. Papillomas were found around their oral cavity, at the op…
View article: Differential survival of 3rd stage larvae of Contracaecum rudolphii type B infecting common bream (Abramis brama) and common carp (Cyprinus carpio)
Differential survival of 3rd stage larvae of Contracaecum rudolphii type B infecting common bream (Abramis brama) and common carp (Cyprinus carpio) Open
The main fish host reaction to an infection with third stage anisakid nematode larvae is a response in which host immune cells (macrophages, granulocytes, lymphocytes) in affected internal organs initially are attracted to the parasite whe…
View article: Family aggregation analysis reveals a heritable background of equine grass sickness (dysautonomia)
Family aggregation analysis reveals a heritable background of equine grass sickness (dysautonomia) Open
Equine grass sickness (also known as dysautonomia) is a life-threatening polyneuropathic disease affecting horses with approx. 80% mortality. Since it’s first description over a hundred years ago, several factors including phenotypic, envi…
View article: Characterization of new, efficient Mycobacterium tuberculosis topoisomerase-I inhibitors and their interaction with human ABC multidrug transporters
Characterization of new, efficient Mycobacterium tuberculosis topoisomerase-I inhibitors and their interaction with human ABC multidrug transporters Open
Drug resistant tuberculosis (TB) is a major worldwide health problem. In addition to the bacterial mechanisms, human drug transporters limiting the cellular accumulation and the pharmacological disposition of drugs also influence the effic…
View article: Discovery of <i>N</i>-[4-(Quinolin-4-yloxy)phenyl]benzenesulfonamides as Novel AXL Kinase Inhibitors
Discovery of <i>N</i>-[4-(Quinolin-4-yloxy)phenyl]benzenesulfonamides as Novel AXL Kinase Inhibitors Open
The overexpression of AXL kinase has been described in many types of cancer. Due to its role in proliferation, survival, migration, and resistance, AXL represents a promising target in the treatment of the disease. In this study we present…
View article: Applicability of fetal thoracic aortic diameter measurement in the prediction of birth weight in Holstein-Friesian cows — Short communication
Applicability of fetal thoracic aortic diameter measurement in the prediction of birth weight in Holstein-Friesian cows — Short communication Open
Transabdominal ultrasonography has been shown to be a useful and reliable method for assessing fetal well-being in horses and cattle. To test the applicability of fetal aortic diameter measurement in cattle, 44 late-term pregnant cows and …
View article: <scp>l</scp>-Alpha Glycerylphosphorylcholine as a Potential Radioprotective Agent in Zebrafish Embryo Model
<span>l</span>-Alpha Glycerylphosphorylcholine as a Potential Radioprotective Agent in Zebrafish Embryo Model Open
This work establishes the zebrafish embryo model for ionizing radiation (IR) modifier research and also evaluates the protective effect of l-alpha glycerylphosphorylcholine (GPC). Embryos were exposed to a single-fraction whole-body gamma …
View article: Pregnancy-associated changes of serum biochemical values in Lipizzaner broodmares
Pregnancy-associated changes of serum biochemical values in Lipizzaner broodmares Open
The aims of this study were to detect physiological changes in blood biochemical parameters throughout gestation, to compare the findings in nonpregnant and pregnant Lipizzaner mares in early-mid and late pregnancy, and to provide referenc…
View article: Fetal heart rate and fetal heart rate variability in Lipizzaner broodmares
Fetal heart rate and fetal heart rate variability in Lipizzaner broodmares Open
Monitoring fetal heart rate (FHR) and fetal heart rate variability (FHRV) helps to understand and evaluate normal and pathological conditions in the foal. The aim of this study was to establish normal heart rate reference values for the on…
View article: CCDC 901358: Experimental Crystal Structure Determination
CCDC 901358: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Sarcocystis-infection of cattle in Hungary
Sarcocystis-infection of cattle in Hungary Open
S. cruzi appears to be the most prevalent Sarcocystis sp. in cattle in Hungary, followed by the zoonotic S. hominis. However, the rate of infection with both species was shown to differ between cattle breeds. The suspected role of Sarcocys…