Ferhat Ferhatoğlu
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View article: The efficacy of second-line chemotherapy in the management of classic and iatrogenic Kaposi sarcoma: An analysis of real-world data
The efficacy of second-line chemotherapy in the management of classic and iatrogenic Kaposi sarcoma: An analysis of real-world data Open
Kaposi sarcoma (KS) is a rare angioproliferative malignancy linked to human herpesvirus 8 infection. While systemic therapy is often unnecessary for classic and iatrogenic KS, advanced cases may require chemotherapy. This study aims to eva…
View article: Therapeutic efficacy of high-dose chemotherapy with autologous stem-cell transplantation in 44 relapsed or refractory germ-cell tumor patients: A retrospective cohort study
Therapeutic efficacy of high-dose chemotherapy with autologous stem-cell transplantation in 44 relapsed or refractory germ-cell tumor patients: A retrospective cohort study Open
Despite having a higher mortality risk than conventional chemotherapeutics, high-dose chemotherapy (HDCT) has the potential to be curative in relapsed/refractory germ-cell tumors. Therefore, selecting the best patient group for this treatm…
View article: Disease characteristics and prognostic factors of colorectal cancer patients with bone metastasis: A real-world data from Turkey
Disease characteristics and prognostic factors of colorectal cancer patients with bone metastasis: A real-world data from Turkey Open
Background: Bone metastasis is rarely seen in colorectal cancer (CRC) patients, and there is insufficient data available regarding such cases. The study aimed to identify the prognostic factors and characteristics associated with overall s…
View article: Is there any diagnostic value of serum caveolin-1 levels on the determination of pancreatic adenocarcinoma?
Is there any diagnostic value of serum caveolin-1 levels on the determination of pancreatic adenocarcinoma? Open
Background: Caveolin-1 (CAV-1) is a vital component in cancer pathogenesis, as its expression determines the survival of patients with cancer. This study investigates CAV-1 serum levels in pancreatic adenocarcinoma (PA) patients and their …
View article: Efficacy of Neoadjuvant Chemotherapy in Lobular and Rare Subtypes of Breast Cancer
Efficacy of Neoadjuvant Chemotherapy in Lobular and Rare Subtypes of Breast Cancer Open
Neoadjuvant chemotherapy, Non-ductal breast cancer, Lobular carcinoma.
View article: The effect of parity, breastfeeding history, and duration on clinical and pathological characteristics of breast cancer patients
The effect of parity, breastfeeding history, and duration on clinical and pathological characteristics of breast cancer patients Open
Breast cancer is seen at a later age in patients who are parous than those who have never given birth. Patients who are parous and have breastfed tend to present with a higher stage of the disease.
View article: Efficacy and outcomes of systemic chemotherapy in posttransplant and immunosuppression associated Kaposi sarcoma: Twenty years experience of a tertiary cancer center
Efficacy and outcomes of systemic chemotherapy in posttransplant and immunosuppression associated Kaposi sarcoma: Twenty years experience of a tertiary cancer center Open
Kaposi sarcoma is a malignant angioproliferative disease, and human herpesvirus-8 plays a major role in its etiology. Iatrogenic Kaposi sarcoma (IKS) can occur in patients undergoing immunosuppressive therapy. The treatment strategy for pa…
View article: Validity and Reliability of Study of Osteoporotic Fractures Index in the Diagnosis of Sarcopenia in Turkish Geriatric Patients
Validity and Reliability of Study of Osteoporotic Fractures Index in the Diagnosis of Sarcopenia in Turkish Geriatric Patients Open
Objective:The objective of this study was to evaluate the reliability and validity of the Turkish version of the study of osteoporotic fractures (SOF) index, and to investigate the prognostic power of the SOF index in predicting the risk f…
View article: Weekly paclitaxel treatment in the first-line therapy of classic Kaposi sarcoma: A real-life study
Weekly paclitaxel treatment in the first-line therapy of classic Kaposi sarcoma: A real-life study Open
Kaposi sarcoma is an angioproliferative disease associated with human herpes virus 8 infection. Classic Kaposi sarcoma (CKS) usually develops in older age. Although CKS often does not require systemic therapy, systemic therapy can be admin…
View article: Fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) regimen in the first-line treatment of metastatic gastric cancer: A single-center experience
Fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) regimen in the first-line treatment of metastatic gastric cancer: A single-center experience Open
Objective: The median survival time for metastatic gastric cancer that has a poor prognosis is usually shorter than 1 year. The fluorouracil, oxaliplatin, and docetaxel (FLOT) regimen is observed to be effective in the neo-adjuvant treatme…
View article: Evaluation of clinical features and risk factors related to late recurrence (>5 years) in patients with breast cancer
Evaluation of clinical features and risk factors related to late recurrence (>5 years) in patients with breast cancer Open
Background/Aim: Over the years, disease-free survival (DFS) has been considerably prolonged with effective treatments in resectable breast cancer patients. However, a limited number of studies evaluating the predictive and prognostic facto…
View article: Systemic Treatment Outcomes of Progressive Medullary Thyroid Carcinoma from the Registries of a Tertiary Cancer Center
Systemic Treatment Outcomes of Progressive Medullary Thyroid Carcinoma from the Registries of a Tertiary Cancer Center Open
Aim:Medullary thyroid carcinoma (MTC) originating from parafollicular C cells is a sporadic endocrine tumor. A unique aspect of the disease is that it is 25% familial and component of multiple endocrine neoplasia 2 syndromes. Surgical rese…
View article: High-dose chemotherapy followed by autologous stem cell transplantation for adult patients With first relapse of Ewing’s sarcoma: A single institution experience
High-dose chemotherapy followed by autologous stem cell transplantation for adult patients With first relapse of Ewing’s sarcoma: A single institution experience Open
The prognosis of patients with Ewing’s sarcoma family of tumors (ESFT) relapse is poor; the 5-year overall survival (OS) is 13%. We evaluated the effectivity of high-dose therapy (HDT) with autologous stem cell transplantation (ASCT) in ad…
View article: Risk Factors for Cutaneous Melanomas and Level of Awareness in Society
Risk Factors for Cutaneous Melanomas and Level of Awareness in Society Open
Background: Skin cancers have become a significant public health problem and increasing over the years.Two crucial risk factors for skin cancers are; phenotypic traits and sun-induced ultraviolet exposure.The risk of disease can be signifi…
View article: Frequency, Demographic and Clinicopathological Characteristics of Skin Cancer Patients Treated and Followed Up in the Medical Oncology Outpatient Clinic
Frequency, Demographic and Clinicopathological Characteristics of Skin Cancer Patients Treated and Followed Up in the Medical Oncology Outpatient Clinic Open
Background: Patients with skin cancer apply to medical oncology outpatient clinics for follow-up after the completion of local treatments or in case of progression despite locoregional treatments (surgical and/or radiotherapy).In this stud…
View article: Toxicity management and efficacy of carboplatin desensitization therapy for recurrent epithelial ovarian carcinoma: A real-world study
Toxicity management and efficacy of carboplatin desensitization therapy for recurrent epithelial ovarian carcinoma: A real-world study Open
Epithelial Ovarian cancer (EOC) is the most lethal gynecologic cancer worldwide. Carboplatin (CP) is the main chemotherapeutic agent in the treatment of ovarian cancer. However, the development of a hypersensitivity reaction (HSR) in 10% t…
View article: Evaluation of clinicopathological features determining treatment response in patients with ALK mutant NSCLC
Evaluation of clinicopathological features determining treatment response in patients with ALK mutant NSCLC Open
ALK (anaplastic lymphoma kinase) inhibitors may be used to treat patients with ALK mutant metastatic nonsmall cell cancer (NSCLC). This study aimed to investigate the factors affecting the patients response to treatment with ALK-positive m…
View article: Evaluation of Prognostic Factors and Trastuzumab-based Treatments in HER2/Neu-positive Metastatic Gastric Cancer
Evaluation of Prognostic Factors and Trastuzumab-based Treatments in HER2/Neu-positive Metastatic Gastric Cancer Open
Gastric cancer, Trastuzumab, Chemotherapy, Prognostic factors.
View article: Cutaneous melanoma survival rates of the elderly are not worse than those of the young, yet they have some specific differences
Cutaneous melanoma survival rates of the elderly are not worse than those of the young, yet they have some specific differences Open
Introduction: The incidence of cutaneous melanoma among the elderly has increased significantly. Unfavorable survival rates are associated with insufficient patient managements and poor prognostic features in the elderly. We aimed to compa…
View article: Outcomes of thymoma after multimodal therapy and determinants of survival: A 16-year experience of a tertiary cancer center
Outcomes of thymoma after multimodal therapy and determinants of survival: A 16-year experience of a tertiary cancer center Open
Background: In this study, we aimed to evaluate the factors that contribute to survival outcomes in patients with thymoma treated with multimodal approaches. Methods: A total of 203 patients (105 males, 98 females; median age: 49 years; ra…
View article: Does Nutritional Status Affect Treatment Tolarability, Response and Survival in Metastatic Colorectal Cancer Patients? Results of a Prospective Multicenter Study
Does Nutritional Status Affect Treatment Tolarability, Response and Survival in Metastatic Colorectal Cancer Patients? Results of a Prospective Multicenter Study Open
Background: The efficacy and tolerability of modern cytotoxic chemotherapy regimens used in malnourished metastatic colorectal cancer (mCRC) patients is uncertain. The aim of this study was to investigate the effect of malnutrition on effi…
View article: P2.17-23 The Role Adjuvant Chemotherapy in Resected Stage 1 NSCLC with High Risk Factors: A Turkish Oncology Group Study
P2.17-23 The Role Adjuvant Chemotherapy in Resected Stage 1 NSCLC with High Risk Factors: A Turkish Oncology Group Study Open
Adjuvant chemotherapy is accepted as a standard treatment for suitable patients who have undergone surgery for T2N0 non-small cell lung cancer with tumors larger than 4 cm. Despite similar relapse rates, the benefit of adjuvant chemotherap…
View article: A rare phenomenon creating dilemma for the surgeon: Pneumoperitoneum after colonoscopy
A rare phenomenon creating dilemma for the surgeon: Pneumoperitoneum after colonoscopy Open
Pneumoperitoneum is free air existence in abdomen and usually caused by the perforation in gastrointestinal system. Peptic ulcer disease is the most common cause of perforation and pneumoperitoneum. The presence of free air in abdomen usua…
View article: Brown Tumors: A Case Report and Review of the Literature
Brown Tumors: A Case Report and Review of the Literature Open
Brown tumors are focal bone lesions, encountered in patients with uncontrolled hyperparathyroidism. They can be located in any part of the skeleton. Clinically significant lesions in the craniofacial bones are rare. Craniofacial involvemen…