Fernanda C. Lessa
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View article: Evaluation of COVID-19 and Influenza-like Illness Surveillance Case Definitions in a Prospective Cohort of Healthcare Personnel in Peru
Evaluation of COVID-19 and Influenza-like Illness Surveillance Case Definitions in a Prospective Cohort of Healthcare Personnel in Peru Open
Background Public health agencies employ case definitions for influenza virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections to optimize surveillance, monitor disease trends, and inform decision-making, particu…
View article: Rapid screening for carbapenemase-producing carbapenem-resistant <i>Enterobacterales</i> : clinical implementation of an immunochromatographic test using broth-enriched rectal swabs
Rapid screening for carbapenemase-producing carbapenem-resistant <i>Enterobacterales</i> : clinical implementation of an immunochromatographic test using broth-enriched rectal swabs Open
Carbapenemase-producing carbapenem-resistant Enterobacterales (CP-CRE) poses a public health issue. Rapid detection of CP-CRE colonization is challenging; existing methods are either expensive or time-consuming. We evaluated an immunochrom…
View article: Incidence of and Risk Factors for SARS-CoV-2 Infection Among Vaccinated Healthcare Workers During Emergence of SARS-CoV-2 Gamma Variant in the Amazon Region, Brazil, 2021
Incidence of and Risk Factors for SARS-CoV-2 Infection Among Vaccinated Healthcare Workers During Emergence of SARS-CoV-2 Gamma Variant in the Amazon Region, Brazil, 2021 Open
Background The emergence of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants poses a significant threat to public health and healthcare workers (HCWs). The SARS-CoV-2 Gamma variant emerged in Manaus, Brazil, in Dec…
View article: COVID-19 Exposure, Protective Measures, Symptom Assessment, and Risk Perception Among Healthcare Workers in Peru: A Longitudinal Cohort Study (2020–2021)
COVID-19 Exposure, Protective Measures, Symptom Assessment, and Risk Perception Among Healthcare Workers in Peru: A Longitudinal Cohort Study (2020–2021) Open
Background The coronavirus disease 2019 (COVID-19) pandemic placed significant pressure on healthcare workers (HCWs) globally, exposing them to high risks of infection and psychological stress. This study assessed dynamic risks and protect…
View article: Antibody Response in Healthcare Workers During the SARS-CoV-2 Gamma Variant Outbreak in Manaus, Brazil
Antibody Response in Healthcare Workers During the SARS-CoV-2 Gamma Variant Outbreak in Manaus, Brazil Open
Background This study aimed to evaluate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–specific binding and neutralizing antibody responses in healthcare workers (HCWs) who received coronavirus disease 2019 (COVID-19) vaccine…
View article: Validation of immunochromatographic test in broth-enriched rectal swab specimens
Validation of immunochromatographic test in broth-enriched rectal swab specimens Open
View article: Multicenter Evaluation of Antibiotic Use and Antibiotic Stewardship Programs in Latin American Hospitals
Multicenter Evaluation of Antibiotic Use and Antibiotic Stewardship Programs in Latin American Hospitals Open
Background There is limited knowledge on the extent of antimicrobial stewardship program (ASP) implementation in health care facilities (HCFs) in Latin America. Methods We performed an evaluation of ASPs in Latin American HCFs from March 2…
View article: Corrigendum to “Nasopharyngeal carriage of Streptococcus pneumoniae among children and their household members in southern Mozambique five years after PCV10 introduction” Vaccine, Volume 47, 15 February 2025, 126,691
Corrigendum to “Nasopharyngeal carriage of Streptococcus pneumoniae among children and their household members in southern Mozambique five years after PCV10 introduction” Vaccine, Volume 47, 15 February 2025, 126,691 Open
View article: Identifying context-specific determinants to inform improvement of antimicrobial stewardship implementation in healthcare facilities in Asia: results from a scoping review and web-based survey among local experts
Identifying context-specific determinants to inform improvement of antimicrobial stewardship implementation in healthcare facilities in Asia: results from a scoping review and web-based survey among local experts Open
International guidelines are available for the assessment and improvement of antimicrobial stewardship (AMS) programmes: an important strategy to address the escalating global antimicrobial resistance problem. However, existing AMS assessm…
View article: Utilizing Whole Genome Sequencing to Investigate a COVID-19 Cluster Among Healthcare Workers in a Tertiary Care Facility in the Philippines: Insights and Implications for Infection Prevention and Control
Utilizing Whole Genome Sequencing to Investigate a COVID-19 Cluster Among Healthcare Workers in a Tertiary Care Facility in the Philippines: Insights and Implications for Infection Prevention and Control Open
Background The coronavirus disease 2019 (COVID-19) pandemic has highlighted the importance of genomic surveillance and whole genome sequencing (WGS) for identifying mutations and supporting epidemiologic investigations. Healthcare workers …
View article: P-186. Trends in Antimicrobial Resistance Among Adults Across 6 Hospitals in Argentina, Brazil, and Chile, 2018-2022
P-186. Trends in Antimicrobial Resistance Among Adults Across 6 Hospitals in Argentina, Brazil, and Chile, 2018-2022 Open
Background In 2019, an estimated 1.27 million deaths were attributed to bacterial antimicrobial resistance (AR) globally. During the Coronavirus Disease 2019 (COVID-19) Pandemic, additional strain was placed on healthcare systems that may …
View article: Nasopharyngeal carriage of Streptococcus pneumoniae among children and their household members in southern Mozambique five years after PCV10 introduction
Nasopharyngeal carriage of Streptococcus pneumoniae among children and their household members in southern Mozambique five years after PCV10 introduction Open
View article: Trends in inpatient antibiotic use in Indonesia and the Philippines during the COVID-19 pandemic
Trends in inpatient antibiotic use in Indonesia and the Philippines during the COVID-19 pandemic Open
Objective: Increased antibiotic use (AU) has been reported globally during the COVID-19 pandemic despite low rates of bacterial co-infection. We assessed changes in AU during the COVID-19 pandemic in Indonesia and the Philippines. Methods:…
View article: Epidemiology of pneumococcal meningitis in sentinel hospital surveillance of Viet Nam, 2015–2018
Epidemiology of pneumococcal meningitis in sentinel hospital surveillance of Viet Nam, 2015–2018 Open
Background Streptococcus pneumoniae (S. pneumoniae) , Haemophilus influenzae (H. influenzae) , and Neisseria meningitidis ( N. meningitidis ) are leading causes of childhood bacterial meningitis and preventable by vaccines. The aim of this…
View article: Antibiotic Use in Medical–Surgical Intensive Care Units and General Wards in Latin American Hospitals
Antibiotic Use in Medical–Surgical Intensive Care Units and General Wards in Latin American Hospitals Open
Background The objective of this study was to identify antibiotic stewardship (AS) opportunities in Latin American medical–surgical intensive care units (MS-ICUs) and general wards (Gral-wards). Methods We conducted serial cross-sectional …
View article: Long-term impact of 10-valent pneumococcal conjugate vaccine in Kenya: Nasopharyngeal carriage among children in a rural and an urban site six years after introduction
Long-term impact of 10-valent pneumococcal conjugate vaccine in Kenya: Nasopharyngeal carriage among children in a rural and an urban site six years after introduction Open
Six years post-PCV10-GSK introduction, the prevalence of pneumococcal carriage among children has decreased, and the impact of PCV10-GSK on vaccine-type carriage has plateaued. Kenya recently changed from PCV10-GSK to Pneumosil™ (Serum Ins…
View article: Impact of Transitioning to Single-Patient Rooms on Prevention of Multidrug-Resistant Organisms in a Resource-Limited Facility
Impact of Transitioning to Single-Patient Rooms on Prevention of Multidrug-Resistant Organisms in a Resource-Limited Facility Open
Background: Healthcare-associated infections (HAI) substantially increase hospital costs and lead to poor patient outcomes, particularly when caused by multidrug-resistant organisms (MDRO). To decrease MDRO transmission, isolation of colon…
View article: Knowledge, attitudes and perceptions of Latin American healthcare workers relating to antibiotic stewardship and antibiotic use: a cross-sectional multi-country study
Knowledge, attitudes and perceptions of Latin American healthcare workers relating to antibiotic stewardship and antibiotic use: a cross-sectional multi-country study Open
Background The burden of antimicrobial resistance (AMR) in Latin America is high. Little is known about healthcare workers’ (HCWs) knowledge, attitudes, and perceptions of antimicrobial stewardship (AS), AMR, and antibiotic use (AU) in the…
View article: 1240. Perceptions of Antimicrobial Stewardship and Antibiotic Use by Healthcare Workers in Latin America
1240. Perceptions of Antimicrobial Stewardship and Antibiotic Use by Healthcare Workers in Latin America Open
Background The burden of antimicrobial resistance (AMR) in Latin America is high. Little is known about healthcare workers’ (HCWs) perceptions of antimicrobial stewardship (AS) and antibiotic use (AU) in the region. Methods HCWs from 42 ho…
View article: Defining access without excess: expanding appropriate use of antibiotics targeting multidrug-resistant organisms
Defining access without excess: expanding appropriate use of antibiotics targeting multidrug-resistant organisms Open
View article: Antibiotic Resistance: A Global Problem and the Need to Do More
Antibiotic Resistance: A Global Problem and the Need to Do More Open
View article: Antibiotic Consumption During the Coronavirus Disease 2019 Pandemic and Emergence of Carbapenemase-Producing <i>Klebsiella pneumoniae</i> Lineages Among Inpatients in a Chilean Hospital: A Time-Series Study and Phylogenomic Analysis
Antibiotic Consumption During the Coronavirus Disease 2019 Pandemic and Emergence of Carbapenemase-Producing <i>Klebsiella pneumoniae</i> Lineages Among Inpatients in a Chilean Hospital: A Time-Series Study and Phylogenomic Analysis Open
Background The impact of coronavirus disease 2019 (COVID-19) on antimicrobial use (AU) and resistance has not been well evaluated in South America. These data are critical to inform national policies and clinical care. Methods At a tertiar…
View article: Prescribing of Outpatient Antibiotics Commonly Used for Respiratory Infections Among Adults Before and During the Coronavirus Disease 2019 Pandemic in Brazil
Prescribing of Outpatient Antibiotics Commonly Used for Respiratory Infections Among Adults Before and During the Coronavirus Disease 2019 Pandemic in Brazil Open
Background The coronavirus disease 2019 (COVID-19) pandemic may have impacted outpatient antibiotic prescribing in low- and middle-income countries such as Brazil. However, outpatient antibiotic prescribing in Brazil, particularly at the p…
View article: Deep Dive Into Gaps and Barriers to Implementation of Antimicrobial Stewardship Programs in Hospitals in Latin America
Deep Dive Into Gaps and Barriers to Implementation of Antimicrobial Stewardship Programs in Hospitals in Latin America Open
Background Antimicrobial resistance has worsened in Latin America. There is an urgent need to understand the development of antimicrobial stewardship programs (ASPs) and the barriers to implementing effective ASPs in light of limited natio…
View article: Trends in Inpatient Antibiotic Use Among Adults Hospitalized During the Coronavirus Disease 2019 Pandemic in Argentina, Brazil, and Chile, 2018–2021
Trends in Inpatient Antibiotic Use Among Adults Hospitalized During the Coronavirus Disease 2019 Pandemic in Argentina, Brazil, and Chile, 2018–2021 Open
Background High rates of antibiotic use (AU) among inpatients with coronavirus disease 2019 (COVID-19) despite low rates of bacterial coinfection and secondary infection have been reported. We evaluated the impact of the COVID-19 pandemic …
View article: Impact of the COVID-19 pandemic on inpatient antibiotic use in Indonesia and the Philippines
Impact of the COVID-19 pandemic on inpatient antibiotic use in Indonesia and the Philippines Open
Background: The coronavirus disease 2019 (COVID-19) pandemic severely affected Southeast Asia, with >35 million cases and ~360,000 deaths. Despite relatively low rates of secondary bacterial infection among inpatients with COVID-19, severa…
View article: Nasopharyngeal colonization by Streptococcus pneumoniae in children and adults before the introduction of the 10-valent conjugate vaccine, Paraguay
Nasopharyngeal colonization by Streptococcus pneumoniae in children and adults before the introduction of the 10-valent conjugate vaccine, Paraguay Open
Streptococcus pneumoniae is a cause of invasive diseases such as pneumonia, meningitis, and other serious infections among children and adults in Paraguay. This study was conducted to establish S . pneumoniae baseline prevalence, serotype …
View article: S1 Table. Pneumococcal carriage dataset Paraguay
S1 Table. Pneumococcal carriage dataset Paraguay Open
Database containing 1,444 nasopharyngeal swabs, 718 from children aged 2 to 59 months and 726 from healthy adults ≥ 60 years, taken between April and July 2012.
View article: S1 Table. Pneumococcal carriage dataset Paraguay
S1 Table. Pneumococcal carriage dataset Paraguay Open
Database containing 1,444 nasopharyngeal swabs, 718 from children aged 2 to 59 months and 726 from healthy adults ≥ 60 years, taken between April and July 2012.
View article: S1 Table. Pneumococcal carriage dataset Paraguay
S1 Table. Pneumococcal carriage dataset Paraguay Open
Database containing 1,444 nasopharyngeal swabs, 718 from children aged 2 to 59 months and 726 from healthy adults ≥ 60 years, taken between April and July 2012.