Massimo Lombardi
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View article: The New Frontier in Small-Cell Lung Cancer: Can Atezolizumab Ensure Enduring Stability?
The New Frontier in Small-Cell Lung Cancer: Can Atezolizumab Ensure Enduring Stability? Open
Small-cell lung cancer (SCLC) is an aggressive malignancy with poor prognosis despite initial responsiveness to chemotherapy. Platinum-based chemotherapy with etoposide has long been the standard first-line treatment, but recent advances i…
View article: IMPORTÂNCIA DA CULTURA E DO ANTIBIOGRAMA NA IDENTIFICAÇÃO E MANEJO DA UROLITÍASE POR ESTRUVITA EM CÃES
IMPORTÂNCIA DA CULTURA E DO ANTIBIOGRAMA NA IDENTIFICAÇÃO E MANEJO DA UROLITÍASE POR ESTRUVITA EM CÃES Open
View article: Cardio-Respiratory, Functional and Antalgic Effects of the Integrated Thermal Care Protocol After Breast Cancer Surgery
Cardio-Respiratory, Functional and Antalgic Effects of the Integrated Thermal Care Protocol After Breast Cancer Surgery Open
Background: In the cardio-respiratory rehabilitation field, thermal medicine represents an interesting complementary therapy approach. It can aid in complex medical contexts characterized by cardio-respiratory deficiency, functional limita…
View article: CarDiac magnEtic Resonance for prophylactic Implantable cardioVerter defibrillAtor ThErapy in Non-Dilated Left Ventricular Cardiomyopathy: a sub-study from the DERIVATE registry
CarDiac magnEtic Resonance for prophylactic Implantable cardioVerter defibrillAtor ThErapy in Non-Dilated Left Ventricular Cardiomyopathy: a sub-study from the DERIVATE registry Open
Aims Accurate risk stratification for patients with non-dilated left ventricular cardiomyopathy (NDLVC) remains challenging due to lack of dedicated clinical trials. This post hoc analysis aims to delineate the arrhythmic risk and assess t…
View article: Insights in mitral annulus disjunction geometry, prevalence and extent in healthy subjects vs. patients with mitral valve prolapse and non-significant mitral regurgitation
Insights in mitral annulus disjunction geometry, prevalence and extent in healthy subjects vs. patients with mitral valve prolapse and non-significant mitral regurgitation Open
View article: Unveiling early cardiac remodelling in mitral valve prolapse with non-significant mitral regurgitation: A comprehensive CMR study
Unveiling early cardiac remodelling in mitral valve prolapse with non-significant mitral regurgitation: A comprehensive CMR study Open
View article: Liquid biopsy-based technologies: a promising tool for biomarker identification in her2-low breast cancer patients for improved therapeutic outcomes
Liquid biopsy-based technologies: a promising tool for biomarker identification in her2-low breast cancer patients for improved therapeutic outcomes Open
The molecular classification of breast cancer plays a pivotal role in developing personalized treatment strategies, with the aim of improving therapeutic outcomes. Despite significant advancements, current diagnostic workflows are hindered…
View article: Cardiovascular magnetic resonance insights into anomalies of the mitral valve apparatus in Fabry cardiomyopathy and hypertrophic cardiomyopathy
Cardiovascular magnetic resonance insights into anomalies of the mitral valve apparatus in Fabry cardiomyopathy and hypertrophic cardiomyopathy Open
Background and aims Despite different etiopathogenesis, Fabry Disease cardiomyopathy (FDc) and sarcomeric hypertrophic cardiomyopathy (HCM) share a similar hypertrophic phenotype, including anomalies of the mitral valve apparatus (AMVA). S…
View article: Diabetic cardiomyopathy: pathophysiology, imaging assessment and therapeutical strategies
Diabetic cardiomyopathy: pathophysiology, imaging assessment and therapeutical strategies Open
View article: When Paying Attention Pays Back: Missense Mutation c.1006G>A p. (Val336Ile) in PRKAG2 Gene Causing Left Ventricular Hypertrophy and Conduction Abnormalities in a Caucasian Patient: Case Report and Literature Review
When Paying Attention Pays Back: Missense Mutation c.1006G>A p. (Val336Ile) in PRKAG2 Gene Causing Left Ventricular Hypertrophy and Conduction Abnormalities in a Caucasian Patient: Case Report and Literature Review Open
PRKAG2 cardiomyopathy is a rare genetic disorder that manifests early in life with an autosomal dominant inheritance pattern. It harbors left ventricular hypertrophy (LVH), ventricular pre-excitation and progressively worsening conduction …
View article: Left ventricle diastolic vortex ring characterization in ischemic cardiomyopathy: insight into atrio-ventricular interplay
Left ventricle diastolic vortex ring characterization in ischemic cardiomyopathy: insight into atrio-ventricular interplay Open
View article: Effects of Enzyme Replacement Therapy on Cardiac MRI Findings in Fabry Disease: A Systematic Review and Meta-Analysis
Effects of Enzyme Replacement Therapy on Cardiac MRI Findings in Fabry Disease: A Systematic Review and Meta-Analysis Open
Purpose To perform a systematic review and meta-analysis to assess the effect of enzyme replacement therapy on cardiac MRI parameters in patients with Fabry disease. Materials and Methods A systematic literature search was conducted from J…
View article: Cardiac magnetic resonance in the assessment of the anomalous right coronary artery originating from the left sinus of Valsalva
Cardiac magnetic resonance in the assessment of the anomalous right coronary artery originating from the left sinus of Valsalva Open
no abstract available
View article: Lumped-parameter model as a non-invasive tool to assess coronary blood flow in AAOCA patients
Lumped-parameter model as a non-invasive tool to assess coronary blood flow in AAOCA patients Open
Ceserani V, Lo Rito M, Agnifili ML, Pascaner AF, Rosato A, Anglese S, Deamici M, Negri J, Corrado C, Bedogni F, Secchi F, Lombardi M, Auricchio F, Frigiola A, Conti M. Lumped-parameter model as a non-invasive tool to assess coronary blood …
View article: Lumped-parameter model as a non-invasive tool to assess coronary blood flow in AAOCA patients
Lumped-parameter model as a non-invasive tool to assess coronary blood flow in AAOCA patients Open
Ceserani V, Lo Rito M, Agnifili ML, Pascaner AF, Rosato A, Anglese S, Deamici M, Negri J, Corrado C, Bedogni F, Secchi F, Lombardi M, Auricchio F, Frigiola A, Conti M. Lumped-parameter model as a non-invasive tool to assess coronary blood …
View article: Impaired Left Atrial Function as a Sign of Diastolic Dysfunction and Heart Failure in Congenitally Corrected Transposition of Great Arteries
Impaired Left Atrial Function as a Sign of Diastolic Dysfunction and Heart Failure in Congenitally Corrected Transposition of Great Arteries Open
View article: Left Ventricle Diastolic Vortex Ring Characterization in Ischemic Cardiomyopathy: Insight into Atrio-ventricular Interplay
Left Ventricle Diastolic Vortex Ring Characterization in Ischemic Cardiomyopathy: Insight into Atrio-ventricular Interplay Open
View article: Fabry Disease Mistaken for HCM: The Diagnostic Impact of T1 Mapping
Fabry Disease Mistaken for HCM: The Diagnostic Impact of T1 Mapping Open
View article: Arrhythmic Mitral Valve Prolapse Phenotype: An Unsupervised Machine-learning Analysis Using a Multi-center Registry
Arrhythmic Mitral Valve Prolapse Phenotype: An Unsupervised Machine-learning Analysis Using a Multi-center Registry Open
View article: Unveiling the Distinctive Phenotypes of Arrhythmic Mitral Valve Prolapse by High-density Myocardial Strain Imaging and Late-gadolinium-enhancement Microstructure Analysis
Unveiling the Distinctive Phenotypes of Arrhythmic Mitral Valve Prolapse by High-density Myocardial Strain Imaging and Late-gadolinium-enhancement Microstructure Analysis Open
View article: Digital Ulcers and Ventricular Arrhythmias as Red Flags to Predict Replacement Myocardial Fibrosis in Systemic Sclerosis
Digital Ulcers and Ventricular Arrhythmias as Red Flags to Predict Replacement Myocardial Fibrosis in Systemic Sclerosis Open
Background: Cardiac involvement in systemic sclerosis (SSc) affects the prognosis of the disease. Echocardiography is the first line imaging tool to detect cardiac involvement, but it is not able to routinely detect myocardial fibrosis. La…
View article: Sex differences in cognitive impairment and association with all-cause mortality: a report from a contemporary cohort of patients with atrial fibrillation
Sex differences in cognitive impairment and association with all-cause mortality: a report from a contemporary cohort of patients with atrial fibrillation Open
Background Cognitive impairment (Cogn-Imp) in patients with atrial fibrillation (AF) has been associated with adverse outcomes. The impact of sex on the association between AF and Cogn-Imp is complex and there are limited data on specific …
View article: Diastolic disfunction in systemic right ventricle: a cardiac magnetic resonance study on atrial function in congenital corrected transposition of great arteries patients
Diastolic disfunction in systemic right ventricle: a cardiac magnetic resonance study on atrial function in congenital corrected transposition of great arteries patients Open
Background congenital corrected transposition of great arteries (ccTGA) leads to systemic position of the right ventricle (sRV). Patients with ccTGA are usually asymptomatic in the first decades of life but over time sRV will fail to suppo…
View article: Cardiovascular Magnetic Resonance in Patients with Cardiac Electronic Devices: Evidence from a Multicenter Study
Cardiovascular Magnetic Resonance in Patients with Cardiac Electronic Devices: Evidence from a Multicenter Study Open
Background: Most recent cardiac implantable electronic devices (CIEDs) can safely undergo a cardiovascular magnetic resonance (CMR) scan under certain conditions, but metal artifacts may degrade image quality. The aim of this study was to …
View article: Lumped-parameter model as a non-invasive tool to assess coronary blood flow in AAOCA patients
Lumped-parameter model as a non-invasive tool to assess coronary blood flow in AAOCA patients Open
View article: Endothelial dysfunction and P2X7 antagonism in TToP system
Endothelial dysfunction and P2X7 antagonism in TToP system Open
View article: Diastolic vortex ring derangements in ischemic cardiomyopathy left ventricles: a 4D Flow MRI study
Diastolic vortex ring derangements in ischemic cardiomyopathy left ventricles: a 4D Flow MRI study Open
Funding Acknowledgements Type of funding sources: Private hospital(s). Main funding source(s): This work was supported by IRCCS Policlinico San Donato, a Clinical Research Hospital partially funded by the Italian Ministry of Health. Introd…
View article: Cardiac magnetic resonance phenotypes and cardiovascular prognosis in classical vs cardiac variant of Fabry disease
Cardiac magnetic resonance phenotypes and cardiovascular prognosis in classical vs cardiac variant of Fabry disease Open
Funding Acknowledgements Type of funding sources: None. Background Fabry disease (FD) is an X-linked lysosomal storage disorder due to a deficiency/absence of alfa-galattosidase A enzyme activity. More than 1000 GLA gene mutations have bee…
View article: Ebstein valve rotation angle: a novel quantitative index of anatomical severity and higher clinical risk in Ebstein's anomaly
Ebstein valve rotation angle: a novel quantitative index of anatomical severity and higher clinical risk in Ebstein's anomaly Open
Funding Acknowledgements Type of funding sources: None. Introduction The study aimed to identify cardiovascular magnetic resonance (CMR) imaging parameters representative of Ebstein's Anomaly (EA) anatomical and clinical severity. Material…
View article: Intracavitary blood flow dynamics in the systemic right ventricle: a 4D-Flow MRI study
Intracavitary blood flow dynamics in the systemic right ventricle: a 4D-Flow MRI study Open
Funding Acknowledgements Type of funding sources: None. Background Failure of the systemic right ventricle (SRV) is based on morphological differences between right and left ventricles (RVs and LVs). RV adaptation to systemic afterload inc…