Fernando Revert
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View article: Unicellular ancestry and mechanisms of diversification of Goodpasture antigen–binding protein
Unicellular ancestry and mechanisms of diversification of Goodpasture antigen–binding protein Open
The emergence of the basement membrane (BM), a specialized form of extracellular matrix, was essential in the unicellular transition to multicellularity. However, the mechanism is unknown. Goodpasture antigen-binding protein (GPBP), a BM p…
View article: Selective targeting of collagen IV in the cancer cell microenvironment reduces tumor burden
Selective targeting of collagen IV in the cancer cell microenvironment reduces tumor burden Open
Goodpasture antigen-binding protein (GPBP) is an exportable1 Ser/Thr kinase that induces collagen IV expansion and has been associated with chemoresistance following epithelial-to-mesenchymal transition (EMT). Here we demonstrate that canc…