Importance Climate change can adversely affect mental health, but the association of ambient temperature with psychiatric symptoms remains poorly understood. Objective To assess the association of ambient temperature exposure with internalizing, externalizing, and attention problems in adolescents from 2 population-based birth cohorts in Europe. Design, Setting, and Participants This cohort study analyzed data from the Dutch Generation R Study and the Spanish INMA (Infancia y Medio Ambiente) Project. Generation R …

Whether greenspace affects lung function is unclear. We explored associations between the level of greenness or presence of urban green space near the home with lung function measures taken repeatedly during childhood and adolescence in five European birth cohorts. Lung function was measured by spirometry between six and 22 years (2-3 times), and 9,206 participants from BAMSE (Sweden), GINI/LISA South and GINI/LISA North (Germany), PIAMA (The Netherlands) and INMA (Spain) contributed at least one lung function mea…

Mercury (Hg), particularly methylmercury (MeHg), is a widespread environmental toxicant linked to early-life cardiometabolic risk. This study examined associations between pre- and postnatal total blood mercury (THg) exposure and cardiometabolic outcomes in children, exploring telomere length (TL) as a potential mediator and polymorphisms in the TERT and CLPTM1L genes as effect modifiers. The analysis included 1,301 mother-child pairs from six European cohorts in the HELIX project. THg was measured in maternal and…

Objective The existence of catch-up lung function growth and its predictors is uncertain. We aimed to identify lung function trajectories and their predictors in a population-based birth cohort. Methods We applied group-based trajectory modelling to z-scores of forced expiratory volume in 1 second (zFEV 1 ) and z-scores of forced vital capacity (zFVC) from 1151 children assessed at around 4, 7, 9, 10, 11, 14 and 18 years. Multinomial logistic regression models were used to test whether potential prenatal and postn…

Since its emergence, the COVID-19 pandemic has profoundly and extensively affected global health and society. Numerous studies have focused on detecting SARS-CoV-2 in air samples collected in healthcare indoor spaces, but few have analysed its presence in air samples from other public community spaces. In addition, limited studies have surveyed indoor spaces where it was not known if individuals with COVID-19 were present or had been present at the time of sampling. This study aimed to determine the SARS-CoV-2 gen…