Fiachra Sweeney
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View article: Derivation of a Personalized Congestion Score Using a Chronic Implantable Inferior Vena Cava Management System in Heart Failure: An Analysis From the FUTURE-HF Trial Portfolio
Derivation of a Personalized Congestion Score Using a Chronic Implantable Inferior Vena Cava Management System in Heart Failure: An Analysis From the FUTURE-HF Trial Portfolio Open
View article: Synthetic yeast chromosome XI design provides a testbed for the study of extrachromosomal circular DNA dynamics
Synthetic yeast chromosome XI design provides a testbed for the study of extrachromosomal circular DNA dynamics Open
We describe construction of the synthetic yeast chromosome XI (synXI) and reveal the effects of redesign at non-coding DNA elements. The 660-kb synthetic yeast genome project (Sc2.0) chromosome was assembled from synthesized DNA fra…
View article: Viral emissions into the air and environment after SARS-CoV-2 human challenge: a phase 1, open label, first-in-human study
Viral emissions into the air and environment after SARS-CoV-2 human challenge: a phase 1, open label, first-in-human study Open
UK Vaccine Taskforce of the Department for Business, Energy and Industrial Strategy of Her Majesty's Government.
View article: Safety and performance of a novel implantable sensor in the inferior vena cava under acute and chronic intravascular volume modulation
Safety and performance of a novel implantable sensor in the inferior vena cava under acute and chronic intravascular volume modulation Open
Aims The management of congestion is one of the key treatment targets in heart failure. Assessing congestion is, however, difficult. The purpose of this study was to investigate the safety and dynamic response of a novel, passive, inferior…
View article: Synthetic yeast chromosome XI design enables extrachromosomal circular DNA formation on demand
Synthetic yeast chromosome XI design enables extrachromosomal circular DNA formation on demand Open
Summary We describe construction of the 660 kilobase synthetic yeast chromosome XI ( synXI ) and reveal how synthetic redesign of non-coding DNA elements impact the cell. To aid construction from synthesized 5 to 10 kilobase DNA fragments,…
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View article: Mutations that adapt SARS-CoV-2 to mink or ferret do not increase fitness in the human airway
Mutations that adapt SARS-CoV-2 to mink or ferret do not increase fitness in the human airway Open
SARS-CoV-2 has a broad mammalian species tropism infecting humans, cats, dogs, and farmed mink. Since the start of the 2019 pandemic, several reverse zoonotic outbreaks of SARS-CoV-2 have occurred in mink, one of which reinfected humans an…
View article: Viral Emissions into the Air and Environment after SARS-CoV-2 Human Challenge: A Phase 1, Open Label, First-in-Human Study
Viral Emissions into the Air and Environment after SARS-CoV-2 Human Challenge: A Phase 1, Open Label, First-in-Human Study Open
View article: Mutations that adapt SARS-CoV-2 to mustelid hosts do not increase fitness in the human airway.
Mutations that adapt SARS-CoV-2 to mustelid hosts do not increase fitness in the human airway. Open
SARS-CoV-2 has a broad mammalian species tropism infecting humans, cats, dogs and farmed mink. Since the start of the 2019 pandemic several reverse zoonotic outbreaks of SARS-CoV-2 have occurred in mink, one of which reinfected humans and …
View article: Mutations that adapt SARS-CoV-2 to mustelid hosts do not increase fitness in the human airway
Mutations that adapt SARS-CoV-2 to mustelid hosts do not increase fitness in the human airway Open
SARS-CoV-2 has a broad mammalian species tropism infecting humans, cats, dogs and farmed mink. Since the start of the 2019 pandemic several reverse zoonotic outbreaks of SARS-CoV-2 have occurred in mink, one of which reinfected humans and …