Filia Apostolakou
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View article: Cystatin C as Biomarker for the Evaluation of Renal Outcome in <scp>AL</scp> Amyloidosis
Cystatin C as Biomarker for the Evaluation of Renal Outcome in <span>AL</span> Amyloidosis Open
Cystatin C (CysC) has emerged as a novel and potentially more reliable biomarker for the estimation of glomerular filtration in the general population in patients with various conditions. In AL amyloidosis, the current renal staging system…
View article: Longitudinal Analysis of Antibody Response Following SARS-CoV-2 Infection Depending on Disease Severity: A Prospective Cohort Study
Longitudinal Analysis of Antibody Response Following SARS-CoV-2 Infection Depending on Disease Severity: A Prospective Cohort Study Open
Objective: Severe coronavirus disease 19 (COVID-19) is characterized by a dysregulated inflammatory response, with humoral immunity playing a central role in the disease course. The objective of this study was to assess the immune response…
View article: Immune response and adverse events after vaccination against <scp>SARS‐CoV</scp>‐2 in adult patients with transfusion‐dependent thalassaemia
Immune response and adverse events after vaccination against <span>SARS‐CoV</span>‐2 in adult patients with transfusion‐dependent thalassaemia Open
Summary Patients with transfusion‐dependent thalassaemia (TDT) are considered an at increased‐risk population for severe and/or morbid coronavirus disease 2019 (COVID‐19) infection. Timely vaccination is the main preventive method for seve…
View article: Kinetics of Anti-Sars-Cov-2 Antibody Responses 3 Months Post Complete Vaccination with BNT162b2; A Prospective Study in 283 Health Workers
Kinetics of Anti-Sars-Cov-2 Antibody Responses 3 Months Post Complete Vaccination with BNT162b2; A Prospective Study in 283 Health Workers Open
Background: Levels of neutralizing antibodies (NΑbs) against SARS-CoV-2 correlate with clinically relevant immune protection from COVID-19. However, a slight decline in antibody titers has become evident even at one month following the sec…
View article: Comparative kinetics of SARS-CoV-2 anti-spike protein RBD IgGs and neutralizing antibodies in convalescent and naïve recipients of the BNT162b2 mRNA vaccine versus COVID-19 patients
Comparative kinetics of SARS-CoV-2 anti-spike protein RBD IgGs and neutralizing antibodies in convalescent and naïve recipients of the BNT162b2 mRNA vaccine versus COVID-19 patients Open
View article: Kinetics of Anti-SARS-CoV-2 Antibody Responses 3 Months Post Complete Vaccination with BNT162b2; A Prospective Study in 283 Health Workers
Kinetics of Anti-SARS-CoV-2 Antibody Responses 3 Months Post Complete Vaccination with BNT162b2; A Prospective Study in 283 Health Workers Open
The aim of this study was to investigate the kinetics of neutralizing antibodies (NAbs) and anti-SARS-CoV-2 anti-S-RBD IgGs up to three months after the second vaccination dose with the BNT162b2 mRNA vaccine. NAbs and anti-S-RBD levels wer…
View article: Systemic IL-15, IFN-γ, and IP-10/CXCL10 signature associated with effective immune response to SARS-CoV-2 in BNT162b2 mRNA vaccine recipients
Systemic IL-15, IFN-γ, and IP-10/CXCL10 signature associated with effective immune response to SARS-CoV-2 in BNT162b2 mRNA vaccine recipients Open
View article: Increased Serum Concentrations of High Mobility Group Box 1 (HMGB1) Protein in Children with Autism Spectrum Disorder
Increased Serum Concentrations of High Mobility Group Box 1 (HMGB1) Protein in Children with Autism Spectrum Disorder Open
High mobility group box 1 protein (HMGB1) has been suggested to be involved in the immune dysfunction and inflammation reported in autism spectrum disorder (ASD). We aimed to assess HMGB1 serum concentrations (SCs) in high-functioning ASD …
View article: Age‐dependent and gender‐dependent antibody responses against <scp>SARS‐CoV</scp>‐2 in health workers and octogenarians after vaccination with the <scp>BNT162b2 mRNA</scp> vaccine
Age‐dependent and gender‐dependent antibody responses against <span>SARS‐CoV</span>‐2 in health workers and octogenarians after vaccination with the <span>BNT162b2 mRNA</span> vaccine Open
Efficacy of vaccines against SARS-CoV-2 virus is of great importance to mitigate the Covid-19 pandemic.1 The BNT162b2 mRNA vaccine (Comirnaty) is the first approved by both FDA and EMA, due to its efficacy in apparently healthy adults.2 Re…
View article: Systemic IL-15, IFN-γ and IP-10/CXCL10 Signature Associated With Effective Immune Response in BNT162b2 mRNA Vaccine Recipients
Systemic IL-15, IFN-γ and IP-10/CXCL10 Signature Associated With Effective Immune Response in BNT162b2 mRNA Vaccine Recipients Open
View article: Increased Diurnal Salivary Cortisol and Morning Serum Triglycerides and Decreased Apo A1 Concentrations in Children and Adolescents with Clinical Depression
Increased Diurnal Salivary Cortisol and Morning Serum Triglycerides and Decreased Apo A1 Concentrations in Children and Adolescents with Clinical Depression Open
Data available on possible associations of lipids, steroid levels, and depression are conflicting. This study investigated their possible associations in a sample of youth with depression. Ninety-eight youth with depression and individuall…
View article: Only vulnerable adults show change in chronic low-grade inflammation after contemplative mental training: evidence from a randomized clinical trial
Only vulnerable adults show change in chronic low-grade inflammation after contemplative mental training: evidence from a randomized clinical trial Open
View article: Acute psychosocial stress increases serum BDNF levels: an antagonistic relation to cortisol but no group differences after mental training
Acute psychosocial stress increases serum BDNF levels: an antagonistic relation to cortisol but no group differences after mental training Open
View article: Growth differentiation factor-15 is a new biomarker for survival and renal outcomes in light chain amyloidosis
Growth differentiation factor-15 is a new biomarker for survival and renal outcomes in light chain amyloidosis Open
Key Points GDF-15 level is a new prognostic factor for survival in AL amyloidosis, and its reduction after therapy is associated with better outcome. GDF-15 level is probably the strongest predictor for renal outcomes in patients with AL a…
View article: Salivary biomarkers may measure stress responses in critically ill children
Salivary biomarkers may measure stress responses in critically ill children Open
Objective: Measurement of salivary biomarkers can provide important information regarding hypothalamic–pituitary–adrenal axis activity both under normal conditions as well as in response to psychological or physical stress. Our aim was to …