Filippo Luca Fimognari
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View article: Palliative geriatrics and dementia: key issues and challenges
Palliative geriatrics and dementia: key issues and challenges Open
Palliative care enhances the quality of life for patients and families facing life-threatening illnesses by addressing physical, psychosocial, and spiritual needs. Dementia, characterized by its progressive and terminal trajectory, present…
View article: Glioblastoma cancer: comparing the effectiveness of 3D conformal radiation therapy and volumetric modulated radiotherapy - an artificial intelligence-based survival prediction
Glioblastoma cancer: comparing the effectiveness of 3D conformal radiation therapy and volumetric modulated radiotherapy - an artificial intelligence-based survival prediction Open
This study aimed to evaluate the survival efficacy of different radiotherapy strategies in patients with glioblastoma (GBM). Furthermore, by utilizing various artificial intelligence algorithms and machine learning models, including neural…
View article: A survey among hospital members of the Italian Hospital and Territory Society
A survey among hospital members of the Italian Hospital and Territory Society Open
To describe hospital activities distributed across the national territory, we conducted an online survey, addressed to all hospital members of the Italian Hospital and Territory Society (SIGOT) by email, and disseminated using SIGOT social…
View article: Respiratory failure, underlying acute illnesses, and hospital outcomes: the S. Giovanni-Addolorata–SIGOT GRACE Study
Respiratory failure, underlying acute illnesses, and hospital outcomes: the S. Giovanni-Addolorata–SIGOT GRACE Study Open
Although respiratory failure (RF) is frequent among older medical patients admitted to non-intensive hospital units, inherent data are scarce. We determined whether RF predicted adverse hospital outcomes independently of its causative illn…
View article: Antidepressant use in dementia: Assessing effective strategies for a vulnerable population
Antidepressant use in dementia: Assessing effective strategies for a vulnerable population Open
Depression is closely associated with dementia and may serve as a risk factor, an early symptom, or a prodromal feature, particularly in Alzheimer's disease, the most common form of dementia. It can also emerge during disease progression, …
View article: Clinical activities of out-of-hospital Italian public geriatrics: a survey of members of the Italian Society of Geriatrics Hospital and Territory
Clinical activities of out-of-hospital Italian public geriatrics: a survey of members of the Italian Society of Geriatrics Hospital and Territory Open
The out-of-hospital public geriatrician is a key professional figure to address the challenges of the complexity of old patients and to act as a bridge between general and local medical services and increasingly crowded hospitals. This is …
View article: Analysis of predictive factors for hospitalization outcomes in older patients: the Geriatric Risk Assessment and Care Evaluation (GRACE) study protocol by the <i>Azienda Ospedaliera San Giovanni-Addolorata</i> (AOSGA) and the Italian Society of Hospital and Community Geriatrics (SIGOT)
Analysis of predictive factors for hospitalization outcomes in older patients: the Geriatric Risk Assessment and Care Evaluation (GRACE) study protocol by the <i>Azienda Ospedaliera San Giovanni-Addolorata</i> (AOSGA) and the Italian Society of Hospital and Community Geriatrics (SIGOT) Open
Acute care hospitalization for older people is a major issue in terms of mortality, loss of functional independence, and reduced quality of life. The Geriatric Comprehensive Assessment may be crucial in promoting predictive models of hospi…
View article: Italian out-of-hospital Centers for Cognitive Disorders and Dementias: a survey of members of the Italian Society of Geriatrics Hospital and Territory
Italian out-of-hospital Centers for Cognitive Disorders and Dementias: a survey of members of the Italian Society of Geriatrics Hospital and Territory Open
The Italian Society of Geriatrics Hospital and Territory conducted a survey regarding the Centers for Cognitive Disorders and Dementias in which territorial geriatricians work. The main characteristics of these centers were considered. Par…
View article: A rare case of right-sided chylothorax induced by vertebral osteophytosis in a nonagenarian patient
A rare case of right-sided chylothorax induced by vertebral osteophytosis in a nonagenarian patient Open
Background: Chylothorax is an abnormal accumulation of lymphatic fluid in the pleural cavity, and it develops because of chyle leaking from the thoracic duct. The clinical presentation can be varied, while symptoms depend on its size and t…
View article: Combining high-flow nasal cannula oxygen therapy with repeated toilet bronchoscopies for respiratory failure due to excessive infected airway secretions: a case report and series from a non-intensive hospital ward
Combining high-flow nasal cannula oxygen therapy with repeated toilet bronchoscopies for respiratory failure due to excessive infected airway secretions: a case report and series from a non-intensive hospital ward Open
Fiberoptic bronchoscopy (FBO) has diagnostic or therapeutic purposes but can cause respiratory deterioration, particularly in patients with pre-existing acute respiratory failure (ARF). Non-invasive ventilation (NIV) and high-flow nasal ca…
View article: Position paper on essential strategies for healthy aging: focus on preventing sarcopenia and cardiovascular diseases from the 38<sup>th</sup> National Congress of the Italian Society of Geriatrics Hospital and Territory (SIGOT)
Position paper on essential strategies for healthy aging: focus on preventing sarcopenia and cardiovascular diseases from the 38<sup>th</sup> National Congress of the Italian Society of Geriatrics Hospital and Territory (SIGOT) Open
Italy’s demographic setting is rapidly evolving and is characterized by a substantial increase in the older population segment. This trend, driven by prolonged life expectancy and declining birth rates, positions Italy as a leader in globa…
View article: The Interplay among Respiratory Failure, Delirium, Frailty and Severity of Illness in Hospitalized Older Medical Patients: A Nationwide Multicenter Observational Study
The Interplay among Respiratory Failure, Delirium, Frailty and Severity of Illness in Hospitalized Older Medical Patients: A Nationwide Multicenter Observational Study Open
Background: Prevalence, correlates and outcomes of respiratory failure (RF) were never studied in large populations of older patients hospitalized in acute care medical settings. Little is known about the possible association between RF an…
View article: Improved Arterial Oxygenation by High Flow Nasal Cannula Oxygen Therapy in Older Patients with Severe Respiratory Failure in a Non-intensive Hospital Ward
Improved Arterial Oxygenation by High Flow Nasal Cannula Oxygen Therapy in Older Patients with Severe Respiratory Failure in a Non-intensive Hospital Ward Open
Background. There are scant data about the effectiveness of high flow nasal cannula (HFNC) oxygen therapy in patients hospitalized with severe acute respiratory failure (ARF) in non-intensive medical wards, particularly regarding the effec…
View article: Methemoglobinemia and acute hemolysis induced by high intravenous doses of vitamin C in a COVID-19 patient with unrecognized glucose-6- phosphate-dehydrogenase deficiency
Methemoglobinemia and acute hemolysis induced by high intravenous doses of vitamin C in a COVID-19 patient with unrecognized glucose-6- phosphate-dehydrogenase deficiency Open
In glucose-6-phosphate-dehydrogenase deficiency (favism), exposure to oxidant agents can trigger hemolytic crises. The intravenous administration of very high doses of vitamin C was proposed as a treatment for severe coronavirus disease 20…
View article: Meta-research in geriatric medicine: a survey of the Italian Society of Hospital and Community Geriatrics (SIGOT)
Meta-research in geriatric medicine: a survey of the Italian Society of Hospital and Community Geriatrics (SIGOT) Open
The need for major information in meta-research (i.e. the part of medicine interested in systematic reviews [SRs] and meta-analyses [MAs]) is increasing. In the last years we are observing an exponential rate of publications as SRs/MAs in …
View article: The Multidimensional Prognostic Index (MPI) for the prognostic stratification of hospitalized older patients with COVID-19: a prospective multicenter observational cohort study. Objectives, study design and expected outcomes (MPI_COVID-19)
The Multidimensional Prognostic Index (MPI) for the prognostic stratification of hospitalized older patients with COVID-19: a prospective multicenter observational cohort study. Objectives, study design and expected outcomes (MPI_COVID-19) Open
The emergent coronavirus-19 disease (COVID-19) pandemic posed and still poses serious issues in the management of the inpatients and in the resource allocation, in particular for those patients requiring Intensive Care Unit (ICU) managemen…
View article: Agreement of a Short Form of the Self-Administered Multidimensional Prognostic Index (SELFY-MPI-SF): A Useful Tool for the Self-Assessment of Frailty in Community-Dwelling Older People
Agreement of a Short Form of the Self-Administered Multidimensional Prognostic Index (SELFY-MPI-SF): A Useful Tool for the Self-Assessment of Frailty in Community-Dwelling Older People Open
Alberto Cella,1 Alberto Ferrari,2 Giuseppe Rengo,3 Vincenzo Solfrizzi,4 Nicola Veronese,5 Matteo Puntoni,6 Sabrina Zora,1 Alberto Pilotto,1,4 Filippo Fimognari7 On behalf of the SELFY-MPI SIGOT Investigators1Geriatric Unit, Department of G…
View article: <p>Agreement of a Short Form of the Self-Administered Multidimensional Prognostic Index (SELFY-MPI-SF): A Useful Tool for the Self-Assessment of Frailty in Community-Dwelling Older People</p>
Agreement of a Short Form of the Self-Administered Multidimensional Prognostic Index (SELFY-MPI-SF): A Useful Tool for the Self-Assessment of Frailty in Community-Dwelling Older People Open
The SELFY-MPI-SF showed strong agreement and precision when compared with the standard SELFY-MPI in people aged 65 and older and can therefore be successfully used as a quicker self-administered frailty instrument in community-dwelling old…
View article: Aging changes complexity of heart rate dynamics assessed by entropy and Lyapunov exponent analysis
Aging changes complexity of heart rate dynamics assessed by entropy and Lyapunov exponent analysis Open
In recent years, many research groups are trying to quantify the physiological signals of an individual, proposing new models to assess the complex dynamics of biological control systems. Indeed, life coincides with the good handling of th…
View article: Drug Prescription and Delirium in Older Inpatients
Drug Prescription and Delirium in Older Inpatients Open
Polypharmacy is significantly associated with delirium only in surgical units, raising the issue of the relevance of medication review in different clinical settings. Specific drug classes are associated with delirium depending on the clin…
View article: Delirium, Dementia, and In-Hospital Mortality: The Results From the Italian Delirium Day 2016, A National Multicenter Study
Delirium, Dementia, and In-Hospital Mortality: The Results From the Italian Delirium Day 2016, A National Multicenter Study Open
Delirium and delirium superimposed on dementia were highly prevalent among older hospitalized patients and significantly increased in-hospital mortality. Clinicians should systematically assess these conditions and recognize them as marker…
View article: Wissenschaftlicher Beirat / Impressum / Inhalt
Wissenschaftlicher Beirat / Impressum / Inhalt Open
View article: The Respiratory “Overlap Syndrome”: Efficacy and Usefulness of the Combined Double Bronchodilation
The Respiratory “Overlap Syndrome”: Efficacy and Usefulness of the Combined Double Bronchodilation Open
The coexistence of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea syndrome in a single patient is known as “overlap syndrome,” and worsens the prognosis of the affected subjects. A marked bronchodilation may be us…
View article: Community acquired pneumonia in the elderly: the Pneumonia in Italian Acute Care for Elderly units (PIACE) study protocol by the Italian Society of Hospital and Community Geriatrics (SIGOT)
Community acquired pneumonia in the elderly: the Pneumonia in Italian Acute Care for Elderly units (PIACE) study protocol by the Italian Society of Hospital and Community Geriatrics (SIGOT) Open
Pneumonia is a frequent cause of hospital admission in elderly patients. Diagnosis of pneumonia in elderly persons with comorbidity may be challenging, due to atypical presentation and complex clinical scenarios. Community-acquired pneumon…
View article: The Severity of Acute Illness and Functional Trajectories in Hospitalized Older Medical Patients
The Severity of Acute Illness and Functional Trajectories in Hospitalized Older Medical Patients Open
The severity of illnesses was strongly associated with adverse functional outcomes around hospitalization, but frailty, intended as functional vulnerability to the acute disease before hospitalization, was a stronger predictor of HAD than …