Federico Marchetti
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View article: Multicentre study on nirsevimab: Bayesian analysis reveals persisting risk for preterm infants
Multicentre study on nirsevimab: Bayesian analysis reveals persisting risk for preterm infants Open
Objective To evaluate whether the timing and effectiveness of nirsevimab prophylaxis vary by gestational age. Design Retrospective cohort study conducted during two identical epidemic seasons: 2023–2024 (before nirsevimab introduction) and…
View article: Unraveling the cellular mechanisms of thiopurine-induced pancreatitis in pediatric inflammatory bowel disease: Insights from induced pluripotent stem cell models
Unraveling the cellular mechanisms of thiopurine-induced pancreatitis in pediatric inflammatory bowel disease: Insights from induced pluripotent stem cell models Open
Thiopurines are effective drugs for inflammatory bowel disease, but their use is limited by side effects such as pancreatitis, whose mechanism remains unknown and may be more severe in children. This study investigated in a personalized wa…
View article: Pediatric healthcare service utilization after the end of COVID-19 state of emergency in Northern Italy: a 6-year quasi-experimental study using interrupted time-series analysis
Pediatric healthcare service utilization after the end of COVID-19 state of emergency in Northern Italy: a 6-year quasi-experimental study using interrupted time-series analysis Open
Background Evidence exists on the major disruptions in pediatric healthcare services occurred during the COVID-19 pandemic, but what happened when all restrictions were lifted is unclear. This study examined trends in pediatric hospital ad…
View article: Dexmedetomidine as a Promising Neuroprotective Sedoanalgesic in Neonatal Therapeutic Hypothermia: A Systematic Review and Meta-Analysis
Dexmedetomidine as a Promising Neuroprotective Sedoanalgesic in Neonatal Therapeutic Hypothermia: A Systematic Review and Meta-Analysis Open
Introduction: Hypoxic-ischemic encephalopathy (HIE) is a leading cause of neonatal mortality and neurodevelopmental disabilities. Therapeutic hypothermia (TH) is the standard of care, but optimized sedoanalgesic strategies remain critical.…
View article: Impact of general vs. neuraxial anesthesia on neonatal outcomes in non-elective cesarean sections
Impact of general vs. neuraxial anesthesia on neonatal outcomes in non-elective cesarean sections Open
Background Cesarean section is a common surgical procedure, usually performed under neuraxial anesthesia and, more rarely, under general anesthesia. The choice of anesthesia in cesarean sections can significantly influence neonatal outcome…
View article: Implementation of the WHO Standards to assess quality of paediatric care at the facility level using service users’ perspective as source of data: a multicentre quality improvement study in Italy
Implementation of the WHO Standards to assess quality of paediatric care at the facility level using service users’ perspective as source of data: a multicentre quality improvement study in Italy Open
Objectives There is little experience in the use of the WHO Standards for improving the quality of care (QOC) for children at the facility level. We describe the use of 75 WHO Standard based Quality Measures to assess paediatric QOC, using…
View article: Evaluation of the WHO standards to assess quality of care for children with acute respiratory infections: findings of a baseline multicentre assessment (CHOICE) in Italy
Evaluation of the WHO standards to assess quality of care for children with acute respiratory infections: findings of a baseline multicentre assessment (CHOICE) in Italy Open
Background Experience is lacking on the implementation of the WHO standards for improving the quality of care (QOC) for children at facility level. We describe the use of 10 prioritised WHO standard-based quality measures to assess provisi…
View article: Implementation of the WHO standards to assess quality of care for children with acute pain in EDs: findings of a multicentre study (CHOICE) in Italy
Implementation of the WHO standards to assess quality of care for children with acute pain in EDs: findings of a multicentre study (CHOICE) in Italy Open
Background There is little experience on the use of the WHO Standards for improving the quality of care (QOC) for children. We describe the use of four prioritised WHO Standard-based Quality Measures to assess the provision of care for chi…
View article: Effects of COVID-19-targeted non-pharmaceutical interventions on pediatric emergency department use: a quasi-experimental study interrupted time-series analysis in North Italian hospitals, 2017 to 2022
Effects of COVID-19-targeted non-pharmaceutical interventions on pediatric emergency department use: a quasi-experimental study interrupted time-series analysis in North Italian hospitals, 2017 to 2022 Open
Background The use of Non-Pharmaceutical Interventions (NPIs) during the COVID-19 pandemic is debated. Understanding the consequences these measures may have on vulnerable populations including children and adolescents is important. Method…
View article: Clinical characteristics and diagnostic workup in severe asthma: data from the database of the Italian Pediatric Respiratory Society
Clinical characteristics and diagnostic workup in severe asthma: data from the database of the Italian Pediatric Respiratory Society Open
Although rare in children, severe asthma is responsible for a heavy burden on families and society. Being a rare condition, every center follows only a limited number of patients, and there is a solid rationale for setting up networks to c…
View article: Effects of COVID-19-targeted non-pharmaceutical interventions on pediatric hospital admissions in North Italian hospitals, 2017 to 2022: a quasi-experimental study interrupted time-series analysis
Effects of COVID-19-targeted non-pharmaceutical interventions on pediatric hospital admissions in North Italian hospitals, 2017 to 2022: a quasi-experimental study interrupted time-series analysis Open
Background The use of Non-Pharmaceutical Interventions (NPIs), such as lockdowns, social distancing and school closures, against the COVID-19 epidemic is debated, particularly for the possible negative effects on vulnerable populations, in…
View article: Fetal-Type Rhabdomyoma of the Cheek: A Conservative Management
Fetal-Type Rhabdomyoma of the Cheek: A Conservative Management Open
Extracardiac rhabdomyomas are rare benign mesenchymal tumors diagnosed upon radiological and hystologic investigations and the treatment of choice is surgical exertion. There aren’t any similar cases managed conservatively reported in lite…
View article: Il gioco delle parti: bronchiolite e drepanocitosi
Il gioco delle parti: bronchiolite e drepanocitosi Open
The case of a 2-month-old Senegalese infant with severe anaemia and RSV-related bronchiolitis is described. The Authors stress the role of common infections in leading to the diagnosis of sickle cell anaemia.
View article: La linea dei sintomi in un disturbo da sintomi somatici
La linea dei sintomi in un disturbo da sintomi somatici Open
The case of a 10-year-old boy affected by somatic disorder syndrome is presented. The graphic representation of symptoms and adverse events together with a timeline helped the mother to interpret her child’s disorder and to manage fears an…
View article: La riforma europea della legislazione farmaceutica
La riforma europea della legislazione farmaceutica Open
The European reform of pharmaceutical legislation: more available, more affordable and more innovative medicines: dream or reality?
View article: Maintenance Therapy for Children and Adolescents with Asthma: Guidelines and Recommendations from the Emilia-Romagna Asthma (ERA) Study Group
Maintenance Therapy for Children and Adolescents with Asthma: Guidelines and Recommendations from the Emilia-Romagna Asthma (ERA) Study Group Open
Asthma is the most frequent chronic disease of childhood, affecting up to 20% of children worldwide. The main guidelines on asthma maintenance therapy in pediatrics suggest different approaches and describe different stages of asthma to de…
View article: La meningite da Streptococcus pyogenes: avete visto mai?
La meningite da Streptococcus pyogenes: avete visto mai? Open
The case of a 12-year-old girl presenting with severe headache and a septic status finally diagnosed as mastoiditis related to meningitis due to Streptococcus pyogenes is described.
View article: Multisystem Inflammatory Syndrome in Children: Tools for a Timely Diagnosis in the Emergency Department from an Italian Multicenter Survey
Multisystem Inflammatory Syndrome in Children: Tools for a Timely Diagnosis in the Emergency Department from an Italian Multicenter Survey Open
Objective: To assess the most frequent clinical features of Multisystem Inflammatory Syndrome in children (MIS-C) at presentation to the Emergency Department (ED) in a large multicenter cohort of patients, in order to define useful tools f…
View article: Antibiotic Prophylaxis for the Prevention of Urinary Tract Infections in Children: Guideline and Recommendations from the Emilia-Romagna Pediatric Urinary Tract Infections (UTI-Ped-ER) Study Group
Antibiotic Prophylaxis for the Prevention of Urinary Tract Infections in Children: Guideline and Recommendations from the Emilia-Romagna Pediatric Urinary Tract Infections (UTI-Ped-ER) Study Group Open
Background: Urinary tract infection (UTI) represents one of the most common infectious diseases and a major cause of antibiotic prescription in children. To prevent recurrent infections and long-term complications, low-dose continuous anti…
View article: Frequency and type of domestic injuries among children during COVID-19 lockdown: what changes from the past? An Italian multicentre cohort study
Frequency and type of domestic injuries among children during COVID-19 lockdown: what changes from the past? An Italian multicentre cohort study Open
Accidents are the main cause of injury in children, more than half events happen at home. Aims of this study were to assess if SARS-CoV-2 lockdown influence emergency department (ED) visits due to children domestic accident (DAs) and to id…
View article: SARS-CoV-2-related bronchiolitis: a multicentre international study
SARS-CoV-2-related bronchiolitis: a multicentre international study Open
Background Bronchiolitis is the main acute lower respiratory tract infection in infants. Data regarding SARS-CoV-2-related bronchiolitis are limited. Objective To describe the main clinical characteristics of infants with SARS-CoV-2-relate…
View article: Keep me safe at home! Epidemiological study on domestic injuries among children and risk of hospitalization
Keep me safe at home! Epidemiological study on domestic injuries among children and risk of hospitalization Open
Population Medicine considers the following types of articles:• Research Papers -reports of data from original research or secondary dataset analyses.• Review Papers -comprehensive, authoritative, reviews within the journal's scope.These i…