Filomena Rossi
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View article: New Insights into the Behavior of NHC-Gold Complexes in Cancer Cells
New Insights into the Behavior of NHC-Gold Complexes in Cancer Cells Open
Among the non-platinum antitumor agents, gold complexes have received increased attention owing to their strong antiproliferative effects, which generally occur through non-cisplatin-like mechanisms of action. Several studies have revealed…
View article: Forward Precision Medicine: Micelles for Active Targeting Driven by Peptides
Forward Precision Medicine: Micelles for Active Targeting Driven by Peptides Open
Precision medicine is based on innovative administration methods of active principles. Drug delivery on tissue of interest allows improving the therapeutic index and reducing the side effects. Active targeting by means of drug-encapsulated…
View article: Silver (I) N-Heterocyclic Carbene Complexes: A Winning and Broad Spectrum of Antimicrobial Properties
Silver (I) N-Heterocyclic Carbene Complexes: A Winning and Broad Spectrum of Antimicrobial Properties Open
The evolution of antibacterial resistance has arisen as the main downside in fighting bacterial infections pushing researchers to develop novel, more potent and multimodal alternative drugs.Silver and its complexes have long been used as a…
View article: Systematic overview of soft materials as a novel frontier for MRI contrast agents
Systematic overview of soft materials as a novel frontier for MRI contrast agents Open
Gd(iii)-nanostructurated Constrast Agents (CAs) for Magnetic Resonance Imaging (MRI) can be designed and developed by manipulating soft material, including fibers, hydrogels and nanogels, in the nanometer scale.
View article: Peptide-Based Drug-Delivery Systems in Biotechnological Applications: Recent Advances and Perspectives
Peptide-Based Drug-Delivery Systems in Biotechnological Applications: Recent Advances and Perspectives Open
Peptides of natural and synthetic sources are compounds operating in a wide range of biological interactions. They play a key role in biotechnological applications as both therapeutic and diagnostic tools. They are easily synthesized thank…
View article: Synthesis, Crystal Structure and Anti-leukemic Activity of 4-{4-[(4-(2-Oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl)benzyl]}-3-phenyl-3H-pyrrolo[2,3-c]quinoline
Synthesis, Crystal Structure and Anti-leukemic Activity of 4-{4-[(4-(2-Oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl)benzyl]}-3-phenyl-3H-pyrrolo[2,3-c]quinoline Open
View article: OC-0160: DCIS treated with breast conservative surgery and radiotherapy: a national multicentre experience
OC-0160: DCIS treated with breast conservative surgery and radiotherapy: a national multicentre experience Open
View article: CCDC 888296: Experimental Crystal Structure Determination
CCDC 888296: Experimental Crystal Structure Determination Open
View article: Synthesis and Antiproliferative Effect of Ethyl 4‐[4‐(4‐Substituted Piperidin‐1‐yl)]benzylpyrrolo[1,2‐<i>a</i>]quinoxalinecarboxylate Derivatives on Human Leukemia Cells
Synthesis and Antiproliferative Effect of Ethyl 4‐[4‐(4‐Substituted Piperidin‐1‐yl)]benzylpyrrolo[1,2‐<i>a</i>]quinoxalinecarboxylate Derivatives on Human Leukemia Cells Open
Acute leukemia is a hematological malignancy with high incidence and recurrence rates and is characterized by an accumulation of blasts in bone marrow due to proliferation of immature lymphoid or myeloid cells associated with a blockade of…
View article: CCDC 888295: Experimental Crystal Structure Determination
CCDC 888295: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 888294: Experimental Crystal Structure Determination
CCDC 888294: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Synthesis and evaluation of the cytotoxic activity of novel ethyl 4-[4-(4-substitutedpiperidin-1-yl)]benzyl-phenylpyrrolo[1,2-a]quinoxaline-carboxylate derivatives in myeloid and lymphoid leukemia cell lines
Synthesis and evaluation of the cytotoxic activity of novel ethyl 4-[4-(4-substitutedpiperidin-1-yl)]benzyl-phenylpyrrolo[1,2-a]quinoxaline-carboxylate derivatives in myeloid and lymphoid leukemia cell lines Open
View article: CCDC 891811: Experimental Crystal Structure Determination
CCDC 891811: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 891814: Experimental Crystal Structure Determination
CCDC 891814: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 891815: Experimental Crystal Structure Determination
CCDC 891815: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1014944: Experimental Crystal Structure Determination
CCDC 1014944: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 891817: Experimental Crystal Structure Determination
CCDC 891817: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 891816: Experimental Crystal Structure Determination
CCDC 891816: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 891813: Experimental Crystal Structure Determination
CCDC 891813: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 891812: Experimental Crystal Structure Determination
CCDC 891812: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Conformational Ensembles Explored Dynamically from Disordered Peptides Targeting Chemokine Receptor CXCR4
Conformational Ensembles Explored Dynamically from Disordered Peptides Targeting Chemokine Receptor CXCR4 Open
This work reports on the design and the synthesis of two short linear peptides both containing a few amino acids with disorder propensity and an allylic ester group at the C-terminal end. Their structural properties were firstly analyzed b…