Fiona M. Wood
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View article: Sex-Based Differences in Long-Term Lipid Metabolism, Inflammation and Stress Regulation After Non-Severe Paediatric Burns
Sex-Based Differences in Long-Term Lipid Metabolism, Inflammation and Stress Regulation After Non-Severe Paediatric Burns Open
Paediatric burn injuries are a global health concern with long-term health consequences, such as psychological, immune, and cardiovascular complications, that can persist even after non-severe injuries. Emerging evidence suggests that biol…
View article: Unveiling the Link: The Potential Roles of Vitamin D in Keloid Pathophysiology
Unveiling the Link: The Potential Roles of Vitamin D in Keloid Pathophysiology Open
Keloid disease, a fibroproliferative skin disorder, is characterised by scar tissue growth that extends beyond the original wound boundaries. Despite advancements, current treatments, particularly surgical excision, often result in high re…
View article: Clinical prediction of wound re-epithelisation outcomes in non-severe burn injury using the plasma lipidome
Clinical prediction of wound re-epithelisation outcomes in non-severe burn injury using the plasma lipidome Open
Whilst wound repair in severe burns has received substantial research attention, non-severe burns (0.7), whilst high-density lipoprotein subfractions, phosphatidylinositols, phosphatidylcholines, and phosphatidylserines were associated wit…
View article: Genetic influence on scar vascularity after burn injury in individuals of European ancestry: A prospective cohort study
Genetic influence on scar vascularity after burn injury in individuals of European ancestry: A prospective cohort study Open
After burn injury there is considerable variation in scar outcome, partially due to genetic factors. Scar vascularity is one characteristic that varies between individuals, and this study aimed to identify genetic variants contributing to …
View article: A randomised investigation of film-forming silicone gel in superficial partial thickness face and neck burn patients: Indication of improved early scar pigmentation outcomes
A randomised investigation of film-forming silicone gel in superficial partial thickness face and neck burn patients: Indication of improved early scar pigmentation outcomes Open
Film-forming silicone gel had comparable effects to standard of care emollient on wound healing of superficial partial thickness burns of the face and neck. Silicone treated wounds were associated with a significant improvement in scar pig…
View article: Barriers and Facilitators to the Implementation of 20 Minutes of Cool Running Water into Emergency Clinical Practice as a First Aid Treatment for Burn Injuries: A Mixed Methods Investigation
Barriers and Facilitators to the Implementation of 20 Minutes of Cool Running Water into Emergency Clinical Practice as a First Aid Treatment for Burn Injuries: A Mixed Methods Investigation Open
View article: Nonsevere Burn Induces a Prolonged Systemic Metabolic Phenotype Indicative of a Persistent Inflammatory Response Postinjury
Nonsevere Burn Induces a Prolonged Systemic Metabolic Phenotype Indicative of a Persistent Inflammatory Response Postinjury Open
Globally, burns are a significant cause of injury that can cause substantial acute trauma as well as lead to increased incidence of chronic comorbidity and disease. To date, research has primarily focused on the systemic response to severe…
View article: Living in Western Australia induces some physiological adaptations of seasonal acclimatisation in the surgical burns team
Living in Western Australia induces some physiological adaptations of seasonal acclimatisation in the surgical burns team Open
Seasonal acclimatization is known to result in adaptations that can improve heat tolerance. Staff who operate on burn injuries are exposed to thermally stressful conditions and seasonal acclimatization may improve their thermoeffector resp…
View article: 881 Content Evaluation of First Aid Information of Burn Centre Websites Worldwide
881 Content Evaluation of First Aid Information of Burn Centre Websites Worldwide Open
While the internet is an invaluable resource for both patients and healthcare providers in the management of burns, websites are often unregulated and highly variable in the quality of their content. Burns centres are in the unique positio…
View article: Clinical prediction of wound re-epithelisation outcomes in non-severe burn injury using the plasma lipidome
Clinical prediction of wound re-epithelisation outcomes in non-severe burn injury using the plasma lipidome Open
Whilst wound repair in severe burns has received substantial research attention, non-severe burns (<20% total body surface area) remain relatively understudied, despite causing considerable physiological impact and constituting most of the…
View article: Non-severe burns induce a prolonged systemic metabolic phenotype indicative of a persistent inflammatory response post-injury
Non-severe burns induce a prolonged systemic metabolic phenotype indicative of a persistent inflammatory response post-injury Open
Globally, burns are a significant cause of injury that can cause substantial acute trauma as well as lead to increased incidence of chronic co-morbidity and disease. To date, research has primarily focused on the systemic response to sever…
View article: Sampling the skin surface chemistry for diagnosis and prognosis
Sampling the skin surface chemistry for diagnosis and prognosis Open
Skin and wound blotting are non‐invasive techniques used to sample the skin and wound surface chemistry, whereby a nitrocellulose membrane is applied to an intact or broken cutaneous surface to detect biomarkers. However, there has been no…
View article: Corticosteroid Injection Alone or Combined with Surgical Excision of Keloids versus Other Therapies Including Ionising Radiotherapy: A Systematic Review and Meta-Analysis of Randomised Controlled Trials
Corticosteroid Injection Alone or Combined with Surgical Excision of Keloids versus Other Therapies Including Ionising Radiotherapy: A Systematic Review and Meta-Analysis of Randomised Controlled Trials Open
Keloid scars are difficult to manage and remain a therapeutic challenge. Corticosteroid therapy alone or ionising radiation (radiotherapy) alone or combined with surgery are first-line treatments, but the scientific justification for these…
View article: Two-photon polymerisation 3D printed freeform micro-optics for optical coherence tomography fibre probes
Two-photon polymerisation 3D printed freeform micro-optics for optical coherence tomography fibre probes Open
View article: A population-based comparison study of the mental health of patients with intentional and unintentional burns
A population-based comparison study of the mental health of patients with intentional and unintentional burns Open
Background A number of studies report high prevalence of mental health conditions among burn patients. However there is a need to understand differences in the temporal relationship between mental health conditions and intentional and unin…
View article: Coherency image analysis to quantify collagen architecture: implications in scar assessment
Coherency image analysis to quantify collagen architecture: implications in scar assessment Open
A novel technique for the fast and robust quantification of collagen architecture following scarring.
View article: A retrospective cohort study to compare post-injury admissions for infectious diseases in burn patients, non-burn trauma patients and uninjured people
A retrospective cohort study to compare post-injury admissions for infectious diseases in burn patients, non-burn trauma patients and uninjured people Open
Background Injury triggers a range of systemic effects including inflammation and immune responses. This study aimed to compare infectious disease admissions after burn and other types of injury using linked hospital admissions data. Metho…
View article: Long-term mental health outcomes after unintentional burns sustained during childhood: a retrospective cohort study
Long-term mental health outcomes after unintentional burns sustained during childhood: a retrospective cohort study Open
Background Burns are a devastating injury that can cause physical and psychological issues. Limited data exist on long-term mental health (MH) after unintentional burns sustained during childhood. This study assessed long-term MH admission…
View article: An objective measure for the assessment and management of fluid shifts in acute major burns
An objective measure for the assessment and management of fluid shifts in acute major burns Open
Background Major burns are life threatening. Fluid resuscitation is required for survival to maintain intravascular volumes and prevent hypovolemic shock. Bioimpedance spectroscopy (BIS) has been recognised as a potential method of monitor…
View article: Resistance training for rehabilitation after burn injury: A systematic literature review & meta-analysis
Resistance training for rehabilitation after burn injury: A systematic literature review & meta-analysis Open
Further research with robust methodology is recommended to assess the potential benefit suggested in this review.
View article: Real-Time Bioimpedance Sensing of Antifibrotic Drug Action in Primary Human Cells
Real-Time Bioimpedance Sensing of Antifibrotic Drug Action in Primary Human Cells Open
Fibrotic diseases are among the most serious health issues with severe burdens due to their chronic nature and a large number of patients suffering from the debilitating effects and long-term sequelae. Collagenase treatment is a nonsurgica…
View article: Identification of factors predicting scar outcome after burn injury in children: a prospective case-control study
Identification of factors predicting scar outcome after burn injury in children: a prospective case-control study Open
Background There is a lack of rigorous research investigating the factors that influence scar outcome in children. Improved clinical decision-making to reduce the health burden due to post-burn scarring in children will be guided by eviden…
View article: Radiotherapy and corticosteroids for preventing and treating keloid scars
Radiotherapy and corticosteroids for preventing and treating keloid scars Open
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of corticosteroids and radiotherapy in: treating people with keloids; preventing recurrence of keloid scarring in patients after …
View article: The Western Australia Population-based Burn Injury Project: Using record linkage to examine long-term effects of burn injury
The Western Australia Population-based Burn Injury Project: Using record linkage to examine long-term effects of burn injury Open
ObjectivesWhile the most obvious impact of a burn is a visible scar, there are hidden impacts. The main contributors to adverse health outcomes after burns are the metabolic, inflammatory, immune and endocrine changes that occur in respons…
View article: Burn Injury Leads to Increased Long-Term Susceptibility to Respiratory Infection in both Mouse Models and Population Studies
Burn Injury Leads to Increased Long-Term Susceptibility to Respiratory Infection in both Mouse Models and Population Studies Open
The burn injured cohort contained 14893 adult patients from 1980-2012 after removal of those patients with evidence of smoke inhalation or injury to the respiratory tract. During the study follow-up study a total of 2,884 and 2,625 respira…
View article: The validity and reliability of using ultrasound elastography to measure cutaneous stiffness, a systematic review.
The validity and reliability of using ultrasound elastography to measure cutaneous stiffness, a systematic review. Open
Robust evidence supporting the use of ultrasound elastography as a diagnostic tool in cutaneous conditions is low, however, initial indicators support further research to establish the utility of ultrasound elastography in dermatology.
View article: Increased burn healing time is associated with higher Vancouver Scar Scale score
Increased burn healing time is associated with higher Vancouver Scar Scale score Open
[Formula: see text] Increased burn wound healing time has been shown to influence abnormal scarring. This study hypothesised that scar severity increases commensurate to the increase in time to healing (TTH) of the wound. Wound healing and…
View article: Burns and long-term infectious disease morbidity: A population-based study
Burns and long-term infectious disease morbidity: A population-based study Open
View article: In vivo label-free lymphangiography of cutaneous lymphatic vessels in human burn scars using optical coherence tomography
In vivo label-free lymphangiography of cutaneous lymphatic vessels in human burn scars using optical coherence tomography Open
We present an automated, label-free method for lymphangiography of cutaneous lymphatic vessels in humans in vivo using optical coherence tomography (OCT). This method corrects for the variation in OCT signal due to the confocal func…
View article: The impact of non-severe burn injury on cardiac function and long-term cardiovascular pathology
The impact of non-severe burn injury on cardiac function and long-term cardiovascular pathology Open
Severe burn injury significantly affects cardiovascular function for up to 3 years. However, whether this leads to long-term pathology is unknown. The impact of non-severe burn injury, which accounts for over 80% of admissions in developed…