Firoza Mamdani
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View article: Overexpression of Cancer- and Neurotransmitter-Associated Genes in the Nucleus Accumbens of Smokers
Overexpression of Cancer- and Neurotransmitter-Associated Genes in the Nucleus Accumbens of Smokers Open
The effects of smoking in the human brain were explored at the molecular level in the nucleus accumbens (NAcc), a key brain region involved in tobacco addiction. Gene expression data from post-mortem NAcc were analyzed according to smoking…
View article: Blood-based biomarkers for suicide in depression: moving a step closer to prediction
Blood-based biomarkers for suicide in depression: moving a step closer to prediction Open
View article: Identification of potential blood biomarkers associated with suicide in major depressive disorder
Identification of potential blood biomarkers associated with suicide in major depressive disorder Open
Suicides have increased to over 48,000 deaths yearly in the United States. Major depressive disorder (MDD) is the most common diagnosis among suicides, and identifying those at the highest risk for suicide is a pressing challenge. The obje…
View article: Towards precision medicine for stress disorders: diagnostic biomarkers and targeted drugs
Towards precision medicine for stress disorders: diagnostic biomarkers and targeted drugs Open
The biological fingerprint of environmental adversity may be key to understanding health and disease, as it encompasses the damage induced as well as the compensatory reactions of the organism. Metabolic and hormonal changes may be an info…
View article: Splice-Break: exploiting an RNA-seq splice junction algorithm to discover mitochondrial DNA deletion breakpoints and analyses of psychiatric disorders
Splice-Break: exploiting an RNA-seq splice junction algorithm to discover mitochondrial DNA deletion breakpoints and analyses of psychiatric disorders Open
Deletions in the 16.6 kb mitochondrial genome have been implicated in numerous disorders that often display muscular and/or neurological symptoms due to the high-energy demands of these tissues. We describe a catalogue of 4489 putative mit…
View article: Erratum: Variable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder
Erratum: Variable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder Open
Correction to: Translational Psychiatry (2015) 5, e636; doi:10.1038/tp.2015.134; published online 15 September 2015 In the Acknowledgments section, the funding through The Brain & Behavior Research Foundation (formerly NARSAD) Young Invest…
View article: Targets of polyamine dysregulation in major depression and suicide: Activity-dependent feedback, excitability, and neurotransmission
Targets of polyamine dysregulation in major depression and suicide: Activity-dependent feedback, excitability, and neurotransmission Open
View article: Supplementary Material for: Evidence of Mitochondrial Dysfunction within the Complex Genetic Etiology of Schizophrenia
Supplementary Material for: Evidence of Mitochondrial Dysfunction within the Complex Genetic Etiology of Schizophrenia Open
Genetic evidence has supported the hypothesis that schizophrenia (SZ) is a polygenic disorder caused by the disruption in function of several or many genes. The most common and reproducible cellular phenotype associated with SZ is a reduct…
View article: Supplementary Material for: Evidence of Mitochondrial Dysfunction within the Complex Genetic Etiology of Schizophrenia
Supplementary Material for: Evidence of Mitochondrial Dysfunction within the Complex Genetic Etiology of Schizophrenia Open
Genetic evidence has supported the hypothesis that schizophrenia (SZ) is a polygenic disorder caused by the disruption in function of several or many genes. The most common and reproducible cellular phenotype associated with SZ is a reduct…
View article: Variable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder
Variable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder Open
View article: Evidence of Mitochondrial Dysfunction within the Complex Genetic Etiology of Schizophrenia
Evidence of Mitochondrial Dysfunction within the Complex Genetic Etiology of Schizophrenia Open
Genetic evidence has supported the hypothesis that schizophrenia (SZ) is a polygenic disorder caused by the disruption in function of several or many genes. The most common and reproducible cellular phenotype associated with SZ is a reduct…
View article: Contents Vol. 1, 2015
Contents Vol. 1, 2015 Open