Fizza Tariq
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View article: Exploring the Anti-Carcinogenic Effect of Choline in Limiting the Progression of Breast Cancer in Females
Exploring the Anti-Carcinogenic Effect of Choline in Limiting the Progression of Breast Cancer in Females Open
Background: Breast cancer is one of the most common cancers among females worldwide, influenced by genetic, environmental, and dietary factors. Choline, an essential nutrient, plays a crucial role in cell membrane integrity and DNA methyla…
View article: <i>CYP2C19*17</i> association with higher plasma 4-hydroxy tamoxifen in Pakistani (estrogen-positive) breast cancer patients
<i>CYP2C19*17</i> association with higher plasma 4-hydroxy tamoxifen in Pakistani (estrogen-positive) breast cancer patients Open
Breast cancer (BC) continues to be the most common cancer in the women worldwide. Since estrogen receptor (ER)-positive BC accounts for the majority of newly diagnosed cases, endocrine therapy is advised to utilize either tamoxifen (Tam) o…
View article: Rhesus Isoimmunization: Late-onset Hemolytic Disease of the Newborn Without Jaundice
Rhesus Isoimmunization: Late-onset Hemolytic Disease of the Newborn Without Jaundice Open
Rhesus (Rh) isoimmunization commonly presents with anemia and jaundice of varying intensity in the early postnatal period and is usually treated with phototherapy and exchange transfusion. Rarely, babies with mild or no symptoms at birth m…
View article: Upper GI bleeding: Causes, morbidity and mortality in admitted patients at Tertiary Care Hospital of Karachi.
Upper GI bleeding: Causes, morbidity and mortality in admitted patients at Tertiary Care Hospital of Karachi. Open
Objectives: Acute upper gastrointestinal bleed is one of the most common emergencies. Despite advancement in the medical field, gastrointestinal bleeding still carries significant mortality and fiscal burden on healthcare system. At presen…
View article: Factor XIII deficiency with intracranial haemorrhage
Factor XIII deficiency with intracranial haemorrhage Open
A 5-year-old girl presented to paediatric emergency with fever and seizures for a short duration. At first, meningitis was suspected and management was started empirically. There was no improvement in the clinical condition of the patient …
View article: Genetic Polymorphism of CYP2C19 in Pakistani Population.
Genetic Polymorphism of CYP2C19 in Pakistani Population. Open
CYP2C19 polymorphism is associated with pretreatment drug response prediction, metabolism, and disposition. Pakistan consists of a population comprising of various ethnic groups residing in different regions of the country each claiming di…
View article: Catheter-Based Renal Denervation In Patients With Uncontrolled Hypertension In The Absence Of Antihypertensive Medications (SPYRAL HTN-OFF MED): A Randomised, Sham-Controlled, Proof-Of-Concept Trial
Catheter-Based Renal Denervation In Patients With Uncontrolled Hypertension In The Absence Of Antihypertensive Medications (SPYRAL HTN-OFF MED): A Randomised, Sham-Controlled, Proof-Of-Concept Trial Open
Dear Editor,
We have read, with great interest, the original article titled ‘Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): A randomised, sh…