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View article: Vaccine effectiveness against influenza A in older adults and the effect of chronic conditions: results from the I-MOVE and VEBIS multicentre European hospital case–control studies, 2015/16–2023/24
Vaccine effectiveness against influenza A in older adults and the effect of chronic conditions: results from the I-MOVE and VEBIS multicentre European hospital case–control studies, 2015/16–2023/24 Open
View article: Was severe SARS-CoV-2 substantially spreading in Northern Italy before its first detection in February 2020? An evaluation of pneumonia-associated hospitalization trends from September 2014 to February 2020
Was severe SARS-CoV-2 substantially spreading in Northern Italy before its first detection in February 2020? An evaluation of pneumonia-associated hospitalization trends from September 2014 to February 2020 Open
Retrospective studies identified SARS-CoV-2 worldwide circulation as early as late 2019. In Italy, the first autochthonous COVID-19 case was diagnosed in a Northern Region on 20 February 2020, raising the question whether high numbers of C…
View article: Detection of Dengue virus RNA in Wastewater during a Local Epidemic in Central Italy (August–October 2024)
Detection of Dengue virus RNA in Wastewater during a Local Epidemic in Central Italy (August–October 2024) Open
View article: Assessing the vector competence of Italian Culex pipiens and Aedes albopictus mosquitoes for the re-emerging Oropouche virus
Assessing the vector competence of Italian Culex pipiens and Aedes albopictus mosquitoes for the re-emerging Oropouche virus Open
View article: Risk assessment and perspectives of local transmission of chikungunya and dengue in Italy, a European forerunner
Risk assessment and perspectives of local transmission of chikungunya and dengue in Italy, a European forerunner Open
To address the growing frequency, extension, and size of local arboviral outbreaks in Europe we retrospectively analyzed dengue and chikungunya transmission in Italy from 2006 to 2023. We applied generalized additive models to the records …
View article: Vaccine effectiveness against influenza A in older adults and the effect of chronic conditions: Results from the I-MOVE and VEBIS multicentre European hospital case–control studies, 2015/16–2023/24
Vaccine effectiveness against influenza A in older adults and the effect of chronic conditions: Results from the I-MOVE and VEBIS multicentre European hospital case–control studies, 2015/16–2023/24 Open
Background The Influenza – Monitoring Vaccine Effectiveness (I-MOVE/I-MOVE+) and the Vaccine Effectiveness, Burden and Impact Studies (VEBIS) hospital networks have conducted seasonal multicentre, test-negative, case–control studies in Eur…
View article: Description and comparison of national surveillance systems and response measures for Aedes-borne diseases in France, Italy and Portugal: a benchmarking study, 2023
Description and comparison of national surveillance systems and response measures for Aedes-borne diseases in France, Italy and Portugal: a benchmarking study, 2023 Open
Background Regions of southern Europe are increasingly colonised by Aedes albopictus, with incidence of autochthonous dengue cases rising in recent years. Aim We describe and compare Aedes -borne disease (dengue, chikungunya and Zika) inci…
View article: Retrospective and Prospective Surveillance and Clinical Presentation of Parvovirus B19 in Veneto, Italy, 2024
Retrospective and Prospective Surveillance and Clinical Presentation of Parvovirus B19 in Veneto, Italy, 2024 Open
The recent increase in parvovirus B19 (B19V) infections across Europe has underscored the need for enhanced surveillance. In Italy, B19V surveillance is not mandated nationally. This ambispective (retrospective and prospective) study aimed…
View article: Transmission of autochthonous Aedes-borne arboviruses and related public health challenges in Europe 2007–2023: a systematic review and secondary analysis
Transmission of autochthonous Aedes-borne arboviruses and related public health challenges in Europe 2007–2023: a systematic review and secondary analysis Open
This work was partly funded by the Italian Ministry of Health (Ricerca corrente) and by the European Union (Next Generation EU, Missione 4 Componente 1 CUP H93C22000640007).
View article: Human neuroinvasive Toscana virus infections in Italy from 2016 to 2023: Increased incidence in 2022 and 2023
Human neuroinvasive Toscana virus infections in Italy from 2016 to 2023: Increased incidence in 2022 and 2023 Open
Background Toscana virus (TOSV) is transmitted to humans through bites of infected sand flies. Neuroinvasive TOSV infections are leading causes of meningitis/encephalitis in southern Europe and notifiable in Italy since 2016. In 2022–23, I…
View article: Epidemiology and Rare Clinical Presentations of Parvovirus B19 During the 2024 Outbreak in Veneto, Italy
Epidemiology and Rare Clinical Presentations of Parvovirus B19 During the 2024 Outbreak in Veneto, Italy Open
The recent increase in parvovirus B19 (B19V) infections across Europe has underscored the need for enhanced surveillance. In Italy, where B19V surveillance is not mandated nationally, this study aimed to assess the epidemiological and clin…
View article: Autochthonous dengue outbreak in Marche Region, Central Italy, August to October 2024
Autochthonous dengue outbreak in Marche Region, Central Italy, August to October 2024 Open
Between August and 28 October 2024, 199 autochthonous cases of dengue virus serotype 2 were notified in the city of Fano, central Italy. We describe the ongoing epidemiological and microbiological investigation and public health measures i…
View article: Case-time series study on the short-term impact of meteorological factors on West Nile Virus incidence in Italy at the local administrative unit level, 2012 to 2021
Case-time series study on the short-term impact of meteorological factors on West Nile Virus incidence in Italy at the local administrative unit level, 2012 to 2021 Open
Our findings underscore the influence of temperature and, to a lesser extent, precipitation on WNV incidence in Northern Italy, highlighting the potential of climatic data in developing early warning systems for WNV surveillance and public…
View article: Comparing Aedes-borne disease surveillance systems in Southern Europe: France, Italy and Portugal
Comparing Aedes-borne disease surveillance systems in Southern Europe: France, Italy and Portugal Open
Introduction Colonization by the Aedes albopictus vector, alongside rising autochthonous dengue cases in France and Italy and imported dengue cases in Portugal reflect the emergent risk of Aedes-borne diseases in Southern Europe. In view o…
View article: Impact of the 2023/24 autumn-winter COVID-19 seasonal booster campaign in preventing severe COVID-19 cases in Italy (October 2023–March 2024)
Impact of the 2023/24 autumn-winter COVID-19 seasonal booster campaign in preventing severe COVID-19 cases in Italy (October 2023–March 2024) Open
View article: Increasing situational awareness through nowcasting of the reproduction number
Increasing situational awareness through nowcasting of the reproduction number Open
Background The time-varying reproduction number R is a critical variable for situational awareness during infectious disease outbreaks; however, delays between infection and reporting of cases hinder its accurate estimation in real-time. A…
View article: Estimated number of lives directly saved by COVID-19 vaccination programmes in the WHO European Region from December, 2020, to March, 2023: a retrospective surveillance study
Estimated number of lives directly saved by COVID-19 vaccination programmes in the WHO European Region from December, 2020, to March, 2023: a retrospective surveillance study Open
US Centers for Disease Control and Prevention.
View article: DENV outbreak in Italy: the impact on the National Transfusion Network.
DENV outbreak in Italy: the impact on the National Transfusion Network. Open
View article: Risk of breakthrough infection and hospitalisation after COVID-19 primary vaccination by HIV status in four Italian regions during 2021
Risk of breakthrough infection and hospitalisation after COVID-19 primary vaccination by HIV status in four Italian regions during 2021 Open
View article: Effectiveness against severe COVID-19 of a seasonal booster dose of bivalent (original/Omicron BA.4-5) mRNA vaccines in persons aged ≥60 years: Estimates over calendar time and by time since administration during prevalent circulation of different Omicron subvariants, Italy, 2022–2023
Effectiveness against severe COVID-19 of a seasonal booster dose of bivalent (original/Omicron BA.4-5) mRNA vaccines in persons aged ≥60 years: Estimates over calendar time and by time since administration during prevalent circulation of different Omicron subvariants, Italy, 2022–2023 Open
View article: REPORT of the Workshop: “Building the One Health Workforce in the European Region”
REPORT of the Workshop: “Building the One Health Workforce in the European Region” Open
The Italian National Institute of Health (Istituto Superiore di Sanità – ISS) is implementing an operational research project to contribute to the development of a harmonized training curriculum across the Pan-European Region for in-servic…
View article: REPORT of the Workshop: “Building the One Health Workforce in the European Region”
REPORT of the Workshop: “Building the One Health Workforce in the European Region” Open
The Italian National Institute of Health (Istituto Superiore di Sanità – ISS) is implementing an operational research project to contribute to the development of a harmonized training curriculum across the Pan-European Region for in-servic…
View article: Spatial spread of COVID-19 during the early pandemic phase in Italy
Spatial spread of COVID-19 during the early pandemic phase in Italy Open
Quantifying the potential spatial spread of an infectious pathogen is key to defining effective containment and control strategies. The aim of this study is to estimate the risk of SARS-CoV-2 transmission at different distances in Italy be…
View article: Socioeconomic Inequalities in SARS-CoV-2 Infection and COVID-19 Health Outcomes in Urban Italy During the COVID-19 Vaccine Rollout, January–November 2021
Socioeconomic Inequalities in SARS-CoV-2 Infection and COVID-19 Health Outcomes in Urban Italy During the COVID-19 Vaccine Rollout, January–November 2021 Open
View article: Sex differences in response to COVID-19 mRNA vaccines in Italian population
Sex differences in response to COVID-19 mRNA vaccines in Italian population Open
Since the beginning of mass vaccination campaign for COVID-19 in Italy (December 2020) and following the rapidly increasing vaccine administration, sex differences have been emphasized. Nevertheless, incomplete and frequently incoherent se…
View article: Diagnosis of Imported Dengue and Zika Virus Infections in Italy from November 2015 to November 2022: Laboratory Surveillance Data from a National Reference Laboratory
Diagnosis of Imported Dengue and Zika Virus Infections in Italy from November 2015 to November 2022: Laboratory Surveillance Data from a National Reference Laboratory Open
Dengue (DENV) and Zika (ZIKV) viruses are mosquito-borne human pathogens. In Italy, the presence of the competent vector Aedes albopictus increases the risk of autochthonous transmission, and a national plan for arboviruses prevention, sur…
View article: A comparison of COVID-19 incidence rates across six European countries in 2021
A comparison of COVID-19 incidence rates across six European countries in 2021 Open
International comparisons of COVID-19 incidence rates have helped gain insights into the characteristics of the disease, benchmark disease impact, shape public health measures and inform potential travel restrictions and border control mea…
View article: Estimated Effectiveness of a Primary Cycle of Protein Recombinant Vaccine NVX-CoV2373 Against COVID-19
Estimated Effectiveness of a Primary Cycle of Protein Recombinant Vaccine NVX-CoV2373 Against COVID-19 Open
Importance Protein recombinant vaccine NVX-CoV2373 (Novavax) against COVID-19 was authorized for its use in adults in late 2021, but evidence on its estimated effectiveness in a general population is lacking. Objective To estimate vaccine …
View article: One Health good practices across the European Region: the co-production of a Compendium
One Health good practices across the European Region: the co-production of a Compendium Open
Issue/problem The international and scientific community has been calling for many years to strengthen prevention and preparedness to threats at the human-animal-environment interface by integrating a systemic approach, such One Health (OH…
View article: Building a European One Health workforce for prevention and preparedness to health threats
Building a European One Health workforce for prevention and preparedness to health threats Open
Background The Quadripartite has elaborated the One Health Joint Plan of Action (2022-2026) (OH JPA) to promote health sustainably and prevent the next pandemic through the One Health (OH) approach. One of the action track of the OH JPA is…