Flávio Hirai
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View article: Economic impact of initial glaucoma treatment with selective laser trabeculoplasty on the Brazilian Public Health System
Economic impact of initial glaucoma treatment with selective laser trabeculoplasty on the Brazilian Public Health System Open
As the initial treatment for primary open-angle glaucoma, selective laser trabeculoplasty exhibited a lower economic impact on SUS than latanoprost and timolol maleate eye drop instillation in all the studied scenarios over one and five-ye…
View article: Meibography health score: a simple grading system for isotretinoin-induced meibography alterations on patients with acne vulgaris
Meibography health score: a simple grading system for isotretinoin-induced meibography alterations on patients with acne vulgaris Open
The meibography health score exhibited good interrater reliability, particularly in severe cases.
View article: Increased inflammatory mediators in the ocular surface tissue in keratoconus.
Increased inflammatory mediators in the ocular surface tissue in keratoconus. Open
In this study, despite higher levels of IL-5 and IL-6 in the tear film of patients with KC, there was no statistically significant difference compared to the control group. However, there was heightened immune activity in the corneal and c…
View article: Long-term visual acuity results from cataract surgery and its association with self-reported visual function: Catquest applicability
Long-term visual acuity results from cataract surgery and its association with self-reported visual function: Catquest applicability Open
Purposes: This study aimed to determine the association of the long-term refractive outcomes of cataract surgery with self-reported visual function obtained using Catquest-9SF. Methods: Patients recruited from the cataract outpatient clini…
View article: Prevalence and risk factors for dry eye disease: the Sao Paulo dry eye study
Prevalence and risk factors for dry eye disease: the Sao Paulo dry eye study Open
Purpose: To estimate the prevalence and risk factors of dry eye disease symptoms and clinical diagnoses in Sao Paulo city, state of Sao Paulo, Brazil. Methods: A total of 582 participants over 18 years old, living in the east zone of Sao P…
View article: Long-term visual acuity results from cataract surgery and its association with self-reported visual function: Catquest applicability
Long-term visual acuity results from cataract surgery and its association with self-reported visual function: Catquest applicability Open
The Catquest-9SF translated into Portuguese proved to be a one-dimensional and psychometrically valid tool to assess visual dysfunction in patients with cataract, and it is successful in objectively quantifying improvements after surgery. …
View article: Prevalence and risk factors for dry eye disease: the Sao Paulo dry eye study
Prevalence and risk factors for dry eye disease: the Sao Paulo dry eye study Open
Dry eye disease prevalence in Sao Paulo city is higher in women than in men. Age and hypertension were stronger risk factors of dry eye disease for women, while eye drops use was a significant indicator of dry eye disease for both sexes.
View article: Prevalence and risk factors for dry eye disease: the Sao Paulo dry eye study
Prevalence and risk factors for dry eye disease: the Sao Paulo dry eye study Open
Purpose: To estimate the prevalence and risk factors of dry eye disease symptoms and clinical diagnoses in Sao Paulo city, state of Sao Paulo, Brazil. Methods: A total of 582 participants over 18 years old, living in the east zone of Sao P…
View article: Upper Eyelid Necrosis Secondary to Hordeolum: A Case Report
Upper Eyelid Necrosis Secondary to Hordeolum: A Case Report Open
We reported a case of upper eyelid necrosis initially misdiagnosed as a preseptal cellulitis following a hordeolum externum resulting in great damage to the upper eyelid (anterior lamella). The infection was successfully treated with surgi…
View article: Impact of a mobile unit on access to eye care in São Paulo, Brazil
Impact of a mobile unit on access to eye care in São Paulo, Brazil Open
The vast majority of patients presenting to a mobile eye health unit required prescriptions for corrective lenses. The rate of detection of ocular disorders was relatively high and the mobile unit provided effective treatment of refractive…
View article: Association between keratoconus, ocular allergy, and sleeping behavior
Association between keratoconus, ocular allergy, and sleeping behavior Open
Purpose: To compare the severity and laterality of keratoconus according to allergic rhinitis, scratching and sleeping habits, and manual dexterity. Methods: Objective assessments regarding allergic rhinitis, eye itching, and sleeping posi…
View article: Association between keratoconus, ocular allergy, and sleeping behavior
Association between keratoconus, ocular allergy, and sleeping behavior Open
The association between higher keratometry values and sleeping position appears to be more significant than that reported between keratometry and itching, or manual dexterity.
View article: Impact of a mobile unit on access to eye care in São Paulo, Brazil
Impact of a mobile unit on access to eye care in São Paulo, Brazil Open
Purpose: The goal of this study was to determine the impact of a mobile eye health unit on access to eye care and to generate a profile of the population requiring ophthalmic care by age, nature of their ophthalmic diseases, and optimal ma…
View article: Reliability of foveal avascular zone measurements in eyes with retinal vein occlusion using optical coherence tomography angiography
Reliability of foveal avascular zone measurements in eyes with retinal vein occlusion using optical coherence tomography angiography Open
Background To evaluate the reliability of foveal avascular zone (FAZ) area measurements using optical coherence tomography angiography (OCTA) in eyes with retinal vein occlusion (RVO). Methods Twenty-five OCTA exams of patients with RVO we…
View article: Database of the alumni performance of the Ophthalmology Stricto sensu Postgraduate Program at Escola Paulista de Medicina, UNIFESP
Database of the alumni performance of the Ophthalmology Stricto sensu Postgraduate Program at Escola Paulista de Medicina, UNIFESP Open
For post-graduate programs, a database with information of its graduates can elucidate whether the goals were achieved based on the proposed teaching, as well as can generate reflections to improve the quality, the courses expectations and…
View article: Cost-effectiveness of Anti-VEGF treatments for age-related macular degeneration: a Brazilian perspective
Cost-effectiveness of Anti-VEGF treatments for age-related macular degeneration: a Brazilian perspective Open
From the Brazilian SUS perspective, bevacizumab is more cost-effective than ranibizumab for the treatment of neovascular age-related macular degeneration. Its use could allow potential annual savings in health budget.
View article: Database of the alumni performance of the Ophthalmology Stricto sensu Postgraduate Program at Escola Paulista de Medicina, UNIFESP
Database of the alumni performance of the Ophthalmology Stricto sensu Postgraduate Program at Escola Paulista de Medicina, UNIFESP Open
Purpose To develop a database with social, demographic and professional information of all graduates of the two post-graduate programs in Ophthalmology of EPM-UNIFESP, including their opinions on quality, application, and contribution of t…
View article: Effectiveness of teachers visual acuity test in school screening of children from 3 to 14 years in Sete Barras, Sao Paulo, Brazil.
Effectiveness of teachers visual acuity test in school screening of children from 3 to 14 years in Sete Barras, Sao Paulo, Brazil. Open
View article: Refractive and visual outcomes after Ferrara corneal ring segment implantation at a 60% depth in keratoconic eyes: case series
Refractive and visual outcomes after Ferrara corneal ring segment implantation at a 60% depth in keratoconic eyes: case series Open
Purpose: This report addresses refractive, topographic, visual acuity, and optical coherence tomography outcomes 12 months after femtosecond, laser-assisted insertion of Ferrara intrastromal corneal ring segments in keratoconic eyes at a d…
View article: A case of recurrent keratitis caused by Paecilomyces lilacinus and treated by voriconazole
A case of recurrent keratitis caused by Paecilomyces lilacinus and treated by voriconazole Open
| We describe here a case of a 21-year-old woman who presented with low visual acuity, pain, and hyperemia in the left eye for 45 days. Her eye had extensive corneal infiltrate, with melting and a central perforation that was glued with cy…
View article: Effectiveness of monthly and fortnightly anti-VEGF treatments for age-related macular degeneration
Effectiveness of monthly and fortnightly anti-VEGF treatments for age-related macular degeneration Open
The bi-weekly follow-up was effective and we found no significant differences in efficacy or safety between the treatments with ranibizumab and bevacizumab.
View article: The Use of Topiramate for Weight Loss Causing Acute Glaucoma: A Case Report and Literature Review.
The Use of Topiramate for Weight Loss Causing Acute Glaucoma: A Case Report and Literature Review. Open
Topiramate is a sulfa-containing drug which is able to disrupt the ocular blood barrier. Recently it has gained more popularity, being used in many clinical conditions. Nowadays, the cases of glaucoma induced by topiramate have increased d…
View article: Effectiveness of monthly and fortnightly anti-VEGF treatments for age-related macular degeneration
Effectiveness of monthly and fortnightly anti-VEGF treatments for age-related macular degeneration Open
Purpose: To study the efficacy and safety of treatments with ranibizumab and bevacizumab for exudative age-related macular degeneration. Methods: A parallel randomized clinical trial was conducted to compare the efficacy and safety of thre…
View article: Refractive and visual outcomes after Ferrara corneal ring segment implantation at a 60% depth in keratoconic eyes: case series
Refractive and visual outcomes after Ferrara corneal ring segment implantation at a 60% depth in keratoconic eyes: case series Open
Ferrara intrastromal corneal ring segment insertions at a depth of 60% yield satisfactory visual, refractive, and keratometric results in keratoconic eyes.
View article: A case of recurrent keratitis caused by Paecilomyces lilacinus and treated by voriconazole
A case of recurrent keratitis caused by Paecilomyces lilacinus and treated by voriconazole Open
We describe here a case of a 21-year-old woman who presented with low visual acuity, pain, and hyperemia in the left eye for 45 days. Her eye had extensive corneal infiltrate, with melting and a central perforation that was glued with cyan…
View article: The Efficacy of Topical Bevacizumab and Sunitinib on Corneal Neovascularization in patients with Stevens-Johnson.
The Efficacy of Topical Bevacizumab and Sunitinib on Corneal Neovascularization in patients with Stevens-Johnson. Open
View article: Femtosecond laser-assisted deep anterior lamellar keratoplasty in phototherapeutic keratectomy versus the big-bubble technique in keratoconus
Femtosecond laser-assisted deep anterior lamellar keratoplasty in phototherapeutic keratectomy versus the big-bubble technique in keratoconus Open
Patients with keratoconus treated with FSL-assisted DALK performed using the big-bubble technique fare better than treated with FSL-assisted DALK associated with PTK.
View article: Incidence of anterior segment neovascularization during intravitreal treatment for macular edema secondary to central retinal vein occlusion
Incidence of anterior segment neovascularization during intravitreal treatment for macular edema secondary to central retinal vein occlusion Open
Purpose: To analyze the effects of injections of intravitreal triamcinolone acetonide (IVTA) and intravitreal bevacizumab (IVB) on the incidence rates of anterior segment neovascularization (ASN) and neovascular glaucoma (NVG) in patients …
View article: Long-term outcomes with Boston type 1 keratoprosthesis in ocular burns
Long-term outcomes with Boston type 1 keratoprosthesis in ocular burns Open
The anatomical and functional results support the use of B-Kpro for managing bilateral limbal stem cell deficiency secondary to ocular burns. However, glaucoma should be carefully evaluated, as it is a continuous threat that may result in …
View article: Long-term outcomes with Boston type 1 keratoprosthesis in ocular burns
Long-term outcomes with Boston type 1 keratoprosthesis in ocular burns Open
Purpose: To evaluate the long-term outcomes of Boston type I keratoprosthesis (B-Kpro) in the management of patients with ocular burn injuries. Methods: This prospective study included all patients with ocular burns who underwent B-Kpro im…