Florian Hellmeier
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View article: Virtual Therapy Planning of Aortic Valve Replacement for Preventing Patient-Prosthesis Mismatch
Virtual Therapy Planning of Aortic Valve Replacement for Preventing Patient-Prosthesis Mismatch Open
Background: Recent studies suggest that any degree of patient-prosthesis mismatch (PPM) increases morbidity and mortality after surgical aortic valve replacement (SAVR). We used computational fluid dynamics simulations to test the influenc…
View article: Beyond One-Time Validation: A Framework for Adaptive Validation of Prognostic and Diagnostic AI-based Medical Devices
Beyond One-Time Validation: A Framework for Adaptive Validation of Prognostic and Diagnostic AI-based Medical Devices Open
Prognostic and diagnostic AI-based medical devices hold immense promise for advancing healthcare, yet their rapid development has outpaced the establishment of appropriate validation methods. Existing approaches often fall short in address…
View article: Verification Study of In Silico Computed Intracardiac Blood Flow With 4D Flow MRI
Verification Study of In Silico Computed Intracardiac Blood Flow With 4D Flow MRI Open
These results delineate areas of application of both methods and lay a foundation for larger validation studies and sensitivity analysis for healthy and diseased cases, being an essential step upon clinical translations.
View article: Inter‐model and inter‐modality analysis of left ventricular hemodynamics: Comparative study of two CFD approaches based on echocardiography and magnetic resonance imaging
Inter‐model and inter‐modality analysis of left ventricular hemodynamics: Comparative study of two CFD approaches based on echocardiography and magnetic resonance imaging Open
Computational fluid dynamics (CFD) carry the potential to provide detailed insights into intraventricular hemodynamics and complement in vivo flow measurement techniques. A variety of CFD approaches emerged in recent years, mostly building…
View article: Reconstructed surfaces and measured valve velocities
Reconstructed surfaces and measured valve velocities Open
The reconstructed surfaces and measured valve velocities of the healthy volunteer belonging to the following publication:L. Obermeier, J. Korte, K. Vellguth, F. Barbieri, F. Hellmeier, P. Berg, and L. Goubergrits, Inter-model and inter-mod…
View article: Geometric uncertainty in intracranial aneurysm rupture status discrimination: a two-site retrospective study
Geometric uncertainty in intracranial aneurysm rupture status discrimination: a two-site retrospective study Open
Objectives Assessing the risk associated with unruptured intracranial aneurysms (IAs) is essential in clinical decision making. Several geometric risk parameters have been proposed for this purpose. However, performance of these parameters…
View article: Hemodynamic Modeling of Biological Aortic Valve Replacement Using Preoperative Data Only
Hemodynamic Modeling of Biological Aortic Valve Replacement Using Preoperative Data Only Open
Objectives: Prediction of aortic hemodynamics after aortic valve replacement (AVR) could help optimize treatment planning and improve outcomes. This study aims to demonstrate an approach to predict postoperative maximum velocity, maximum p…
View article: An orifice shape-based reduced order model of patient-specific mitral valve regurgitation
An orifice shape-based reduced order model of patient-specific mitral valve regurgitation Open
Mitral valve regurgitation (MR) is one of the most prevalent valvular heart diseases. Its quantitative assessment is challenging but crucial for treatment decisions. Using computational fluid dynamics (CFD), we developed a reduced order mo…
View article: An orifice shape-based reduced order model of patient-specific mitral valve regurgitation
An orifice shape-based reduced order model of patient-specific mitral valve regurgitation Open
Mitral valve regurgitation (MR) is one of the most prevalent valvular heart diseases. Its quantitative assessment is challenging but crucial for treatment decisions. Using computational fluid dynamics (CFD), we developed a reduced order mo…
View article: Abnormal aortic flow profiles persist after aortic valve replacement in the majority of patients with aortic valve disease: how model-based personalized therapy planning could improve results. A pilot study approach
Abnormal aortic flow profiles persist after aortic valve replacement in the majority of patients with aortic valve disease: how model-based personalized therapy planning could improve results. A pilot study approach Open
OBJECTIVES Complex blood flow profiles in the aorta are known to contribute to vessel dilatation. We studied flow profiles in the aorta in patients with aortic valve disease before and after surgical aortic valve replacement (AVR). METHODS…
View article: MOESM1 of Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH): uncertainty quantification of geometric rupture risk parameters
MOESM1 of Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH): uncertainty quantification of geometric rupture risk parameters Open
Additional file 1. All geometric parameters calculated for the aneurysm geometries provided in frames of MATCH.
View article: Data for "Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH) - Uncertainty quantification of geometric rupture risk parameters"
Data for "Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH) - Uncertainty quantification of geometric rupture risk parameters" Open
This data set contains all 121 aneurysm dome geometries (in STL file format) that were used for calculation of geometric parameters analysed in the publication "Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH) - Uncertainty quantification…
View article: Numerical investigation of the impact of branching vessel boundary conditions on aortic hemodynamics
Numerical investigation of the impact of branching vessel boundary conditions on aortic hemodynamics Open
CFD has gained significant attention as a tool to model aortic hemodynamics. However, obtaining accurate patient-specific boundary conditions still poses a major challenge and represents a major source of uncertainties, which are difficult…
View article: Beyond Pressure Gradients: The Effects of Intervention on Heart Power in Aortic Coarctation
Beyond Pressure Gradients: The Effects of Intervention on Heart Power in Aortic Coarctation Open
clinicaltrials.gov NCT02591940.