Florian Hornsteiner
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View article: Multi-Epitope DC Vaccines with Melanoma Antigens for Immunotherapy of Melanoma
Multi-Epitope DC Vaccines with Melanoma Antigens for Immunotherapy of Melanoma Open
Background/Objectives: The revolution for the treatment of melanoma came with the approval of checkpoint blockade antibodies. However, a substantial proportion of patients show primary or secondary resistance to this type of immunotherapy,…
View article: P-01.12 Impact of glutamate metabolism and its inhibition on melanoma development and immune cells
P-01.12 Impact of glutamate metabolism and its inhibition on melanoma development and immune cells Open
View article: Regulation of NK cell development, maturation, and antitumor responses by the nuclear receptor NR2F6
Regulation of NK cell development, maturation, and antitumor responses by the nuclear receptor NR2F6 Open
View article: Guidelines for preparation and flow cytometry analysis of human nonlymphoid tissue DC
Guidelines for preparation and flow cytometry analysis of human nonlymphoid tissue DC Open
This article is part of the Dendritic Cell Guidelines article series, which provides a collection of state‐of‐the‐art protocols for the preparation, phenotype analysis by flow cytometry, generation, fluorescence microscopy, and functional …
View article: Langerhans cells orchestrate apoptosis of DNA‐damaged keratinocytes upon high‐dose UVB skin exposure
Langerhans cells orchestrate apoptosis of DNA‐damaged keratinocytes upon high‐dose UVB skin exposure Open
Ultraviolet (UV) irradiation of the skin causes mutations that can promote the development of melanoma and nonmelanoma skin cancer. High‐dose UVB exposure triggers a vigorous skin reaction characterized by inflammation resulting in acute s…
View article: Tumor-targeted therapy with BRAF-inhibitor recruits activated dendritic cells to promote tumor immunity in melanoma
Tumor-targeted therapy with BRAF-inhibitor recruits activated dendritic cells to promote tumor immunity in melanoma Open
Background Tumor-targeted therapy causes impressive tumor regression, but the emergence of resistance limits long-term survival benefits in patients. Little information is available on the role of the myeloid cell network, especially dendr…
View article: 169 Unraveling the role of CD64+ DC population in melanoma
169 Unraveling the role of CD64+ DC population in melanoma Open
View article: Guidelines for DC preparation and flow cytometry analysis of mouse nonlymphoid tissues
Guidelines for DC preparation and flow cytometry analysis of mouse nonlymphoid tissues Open
This article is part of the Dendritic Cell Guidelines article series, which provides a collection of state‐of‐the‐art protocols for the preparation, phenotype analysis by flow cytometry, generation, fluorescence microscopy and functional c…
View article: Contents: Eur. J. Immunol. 12'22
Contents: Eur. J. Immunol. 12'22 Open
View article: Mouse dendritic cells and other myeloid subtypes in healthy lymph nodes and skin: 26‐Color flow cytometry panel for immune phenotyping
Mouse dendritic cells and other myeloid subtypes in healthy lymph nodes and skin: 26‐Color flow cytometry panel for immune phenotyping Open
This novel 26-color flow cytometry panel allows the detailed immune phenotyping of the complex network of myeloid cells in murine lymph nodes and skin. With the optimized panel the different murine DC-subsets and other myeloid cell types c…
View article: Skin dendritic cells in melanoma are key for successful checkpoint blockade therapy
Skin dendritic cells in melanoma are key for successful checkpoint blockade therapy Open
Background Immunotherapy with checkpoint inhibitors has shown impressive results in patients with melanoma, but still many do not benefit from this line of treatment. A lack of tumor-infiltrating T cells is a common reason for therapy fail…
View article: Cardioprotective effects of short-term empagliflozin treatment in db/db mice
Cardioprotective effects of short-term empagliflozin treatment in db/db mice Open
Sodium glucose transporter (SGLT)-2 inhibitors have consistently shown cardioprotective effects independent of the glycemic status of treated patients. In this study we aimed to investigate underlying mechanisms of short-term empagliflozin…