Explanipedia

Taxonomic classification of DNA sequences beyond sequence similarity using deep neural networks Open

Florian Mock, Fleming Kretschmer, Anton Kriese, Sebastian Böcker, Manja Marz · 2022

Taxonomic classification, that is, the assignment to biological clades with shared ancestry, is a common task in genetics, mainly based on a genome similarity search of large genome databases. The classification quality depends heavily on …

BERTax: taxonomic classification of DNA sequences with Deep Neural Networks Open

Florian Mock, Fleming Kretschmer, Anton Kriese, Sebastian Böcker, Manja Marz · 2021

Taxonomic classification, i.e., the identification and assignment to groups of biological organisms with the same origin and characteristics, is a common task in genetics. Nowadays, taxonomic classification is mainly based on genome simila…

EpiDope: a deep neural network for linear B-cell epitope prediction Open

Maximilian Collatz, Florian Mock, Emanuel Barth, Martin Hölzer, Konrad Sachse , et al. · 2021

Virus Bioinformatics Open

Nikolaos Pappas, Simon Roux, Martin Hölzer, Kevin Lamkiewicz, Florian Mock , et al. · 2020

Since the discovery of computers, bioinformatics and computational biology have been instrumental in a wide range of discoveries in virology. These include early mathematical models of virus-host interaction, and more recently the analysis…

VIDHOP, viral host prediction with deep learning Open

Florian Mock, Adrian Viehweger, Emanuel Barth, Manja Marz · 2020

Motivation Zoonosis, the natural transmission of infections from animals to humans, is a far-reaching global problem. The recent outbreaks of Zikavirus, Ebolavirus and Coronavirus are examples of viral zoonosis, which occur more frequently…

EpiDope: A Deep neural network for linear B-cell epitope prediction Open

Maximilian Collatz, Florian Mock, Martin Hölzer, Emanuel Barth, Konrad Sachse , et al. · 2020

By binding to specific structures on antigenic proteins, the so-called epitopes, B-cell antibodies can neutralize pathogens. The identification of B-cell epitopes is of great value for the development of specific serodiagnostic assays and …

Supplement Paper: EpiDope: A Deep neural network for linear B-cellepitope prediction Open

Florian Mock, Maximilian Collatz · 2020

Supplement Paper: VIDHOP, viral host prediction with Deep Learning Open

Florian Mock · 2020

Supplementary data for the paper: VIDHOP, viral host prediction with Deep Learning containing all figures and the training data for all 3 virus species

A comprehensive annotation and differential expression analysis of short and long non-coding RNAs in 16 bat genomes Open

Nelly Mostajo, Marie Lataretu, Sebastian Krautwurst, Florian Mock, Daniel Desirò , et al. · 2019

Although bats are increasingly becoming the focus of scientific studies due to their unique properties, these exceptional animals are still among the least studied mammals. Assembly quality and completeness of bat genomes vary a lot and es…

A comprehensive annotation and differential expression analysis of short and long non-coding RNAs in 16 bat genomes Open

Nelly Mostajo Berrospi, Marie Lataretu, Sebastian Krautwurst, Florian Mock, Daniel Desirò , et al. · 2019

Although bats are increasingly becoming the focus of scientific studies due to their unique properties, these exceptional animals are still among the least studied mammals. Assembly quality and completeness of bat genomes vary a lot and es…

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