Florian Ruepp
YOU?
Author Swipe
View article: Kinetic, Spectroscopic, and Computational Investigation of Oxidative Aminative Alkene Cleavage Reveals an N-Iodonium-Iminoiodinane Pathway
Kinetic, Spectroscopic, and Computational Investigation of Oxidative Aminative Alkene Cleavage Reveals an N-Iodonium-Iminoiodinane Pathway Open
The combination of hypervalent iodine(III) oxidants and ammonia sources has been applied in various oxidative aminative transformations of high synthetic value. Central to these reactions is the proposed in situ generation of a four-electr…
View article: Contrasting Solution and Gas‐Phase: Understanding Structure and Reactivity of Gold‐Diazenyl Intermediates
Contrasting Solution and Gas‐Phase: Understanding Structure and Reactivity of Gold‐Diazenyl Intermediates Open
Gold(I)‐catalyzed cross‐coupling reactions with aryldiazonium salts are instrumental in forming C─C and C─N bonds. However, mechanistic details remain unclear, particularly the role of diazenyl intermediates. We employ stoichiometric react…
View article: Metal Electronics Mediate Steric and Coordination Number Effects on Palladium (II) C–X Reductive Elimination
Metal Electronics Mediate Steric and Coordination Number Effects on Palladium (II) C–X Reductive Elimination Open
Reductive elimination is the key bond-forming elementary step in many transition metal catalyzed reactions relevant to the synthesis of pharmaceuticals, materials and fine chemicals. Metal electronics, ancillary ligand sterics and metal co…
View article: Streamlining the Synthesis of Pyridones through Oxidative Amination of Cyclopentenones
Streamlining the Synthesis of Pyridones through Oxidative Amination of Cyclopentenones Open
Herein we report the development of an oxidative amination process for the streamlined synthesis of pyridones from cyclopentenones. Cyclopentenone building blocks can undergo in situ silyl enol ether formation, followed by the introduction…
View article: Streamlining the Synthesis of Pyridones through Oxidative Amination
Streamlining the Synthesis of Pyridones through Oxidative Amination Open
Herein we report the development of an oxidative amination process for the streamlined synthesis of pyridones from cyclopentenones. Cyclopentenone building blocks can undergo in situ silyl enol ether formation, followed by the introduction…