Florian Strasser
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View article: A genome wide association study to identify germline copy number variants associated with cancer cachexia: a preliminary analysis
A genome wide association study to identify germline copy number variants associated with cancer cachexia: a preliminary analysis Open
Background Cancer cachexia is characterized by severe loss of muscle and fat involving a complex interplay of host–tumour interactions. While much emphasis has been placed on understanding the molecular mechanisms associated with cachexia,…
View article: Gemeinsam fr zeitgemsse Evidenz sorgen
Gemeinsam fr zeitgemsse Evidenz sorgen Open
View article: Collaborer pour fournir des preuves actuelles
Collaborer pour fournir des preuves actuelles Open
View article: A genome wide association study to identify germline variants associated with cancer-associated cachexia - a preliminary analysis
A genome wide association study to identify germline variants associated with cancer-associated cachexia - a preliminary analysis Open
Background Cancer cachexia is characterized by severe loss of muscle and fat involving a complex interplay of host-tumor interactions. While much emphasis has been made in understanding the molecular mechanisms associated with cachexia, un…
View article: Evidenz der Komplementrmedizin am Beispiel Integrative Onkologie
Evidenz der Komplementrmedizin am Beispiel Integrative Onkologie Open
Natürlichen» und «Selbermachen» wie körperliche Aktivität [14] und gesunde Ernährung [15]
View article: Preuves de la mdecine complmentaire en oncologie intgrative
Preuves de la mdecine complmentaire en oncologie intgrative Open
La médecine centrée sur le patient, qui tient compte des aspects biopsychosociaux, mais aussi existentiels ou spirituels, joue un rôle essentiel pour les personnes touchées par la maladie.En plus du désir de se soigner par des méthodes nat…
View article: Overcoming barriers to timely recognition and treatment of cancer cachexia: Sharing Progress in Cancer Care Task Force Position Paper and Call to Action
Overcoming barriers to timely recognition and treatment of cancer cachexia: Sharing Progress in Cancer Care Task Force Position Paper and Call to Action Open
Cachexia is a life-threatening disorder affecting an estimated 50-80% of cancer patients. The loss of skeletal muscle mass in patients with cachexia is associated with an increased risk of anticancer treatment toxicity, surgical complicati…
View article: Development of a tool for palliative care needs assessment and intervention: mixed methods research at a Swiss tertiary oncology clinic
Development of a tool for palliative care needs assessment and intervention: mixed methods research at a Swiss tertiary oncology clinic Open
This paper reports on research carried out to understand what elements are most important in a tool that helps oncology professionals to identify patients' unmet needs and provide tailored palliative care interventions. This study demonstr…
View article: Практичні настанови Європейської асоціації клінічного харчування та метаболізму (ESPEN): клінічне харчування при онкологічних захворюваннях
Практичні настанови Європейської асоціації клінічного харчування та метаболізму (ESPEN): клінічне харчування при онкологічних захворюваннях Open
Анотація.Ці практичні настанови засновані на сучасних наукових настановах ESPEN з харчування онкологічних пацієнтів.Для спрощення використання у клінічній практиці настанови ESPEN було скорочено та переведено в блок-схеми.Практичні настано…
View article: A Conceptual Framework For Cautious Escalation Of Anticancer Treatment: How To Optimize Overall Benefit And Obviate The Need For De-Escalation Trials
A Conceptual Framework For Cautious Escalation Of Anticancer Treatment: How To Optimize Overall Benefit And Obviate The Need For De-Escalation Trials Open
View article: Both abundant and rare fungi colonizing Fagus sylvatica ectomycorrhizal root-tips shape associated bacterial communities
Both abundant and rare fungi colonizing Fagus sylvatica ectomycorrhizal root-tips shape associated bacterial communities Open
View article: Towards a novel approach guiding the decision-making process for anticancer treatment in patients with advanced cancer: framework for systemic anticancer treatment with palliative intent
Towards a novel approach guiding the decision-making process for anticancer treatment in patients with advanced cancer: framework for systemic anticancer treatment with palliative intent Open
The SACT-PI Decision Framework integrates subjective patient factors, interpersonal factors, and PC issues into decision-making. Our findings complement existing decision aids and prompt lists by framing DFs in the context of SACT-PI and e…
View article: Evaluation of the G8 Screening Tool in Older Patients with Cancer: A Retrospective Analysis
Evaluation of the G8 Screening Tool in Older Patients with Cancer: A Retrospective Analysis Open
Aim: The aims of this study were to evaluate the results of the Geriatric 8 (G8) screening in patients aged 75 years and over. Findings: Of 2,294 patients screened, 177 were ≥ 75 years. 120 patients (68%) were vulnerable as defined by a G8…
View article: Lenalidomide in cancer cachexia: a randomized trial of an anticancer drug applied for anti‐cachexia
Lenalidomide in cancer cachexia: a randomized trial of an anticancer drug applied for anti‐cachexia Open
Background Cancer cachexia (CC) impacts quality of life, physical function, anticancer treatment response, and survival. Inflammation is a prominent pathomechanism of CC. This small‐scale study sets out to investigate the immunomodulatory …
View article: Diagnostic criteria for cancer cachexia: reduced food intake and inflammation predict weight loss and survival in an international, multi‐cohort analysis
Diagnostic criteria for cancer cachexia: reduced food intake and inflammation predict weight loss and survival in an international, multi‐cohort analysis Open
Background Cancer‐associated weight loss (WL) associates with increased mortality. International consensus suggests that WL is driven by a variable combination of reduced food intake and/or altered metabolism, the latter often represented …
View article: Cancer cachexia in adult patients: ESMO Clinical Practice Guidelines☆
Cancer cachexia in adult patients: ESMO Clinical Practice Guidelines☆ Open
• This ESMO Clinical Practice Guideline provides key recommendations for managing cancer-related cachexia. • It covers screening, assessment and multimodal management of cancer cachexia. • All recommendations were compiled by a multidiscip…
View article: Patterns of integrating palliative care into standard oncology in an early ESMO designated center: a 10-year experience
Patterns of integrating palliative care into standard oncology in an early ESMO designated center: a 10-year experience Open
View article: Natural ghrelin in advanced cancer patients with cachexia, a case series
Natural ghrelin in advanced cancer patients with cachexia, a case series Open
Background Natural ghrelin, a peptide growth hormone secretagogue, has a therapeutic potential in cachexia. We designed a dose‐finding trial of subcutaneous natural ghrelin to improve nutritional intake (NI) in advanced cancer patients. Me…
View article: Managing cancer patients during the COVID-19 pandemic: an ESMO multidisciplinary expert consensus
Managing cancer patients during the COVID-19 pandemic: an ESMO multidisciplinary expert consensus Open
View article: Meaning in life and quality of life: palliative care patients versus the general population
Meaning in life and quality of life: palliative care patients versus the general population Open
Background and objectives Meaning in life (MIL) represent a key topic in palliative care. The aims of this study were to explore (1) the differences in perceived MIL and in the meaning-relevant life areas between a representative sample of…
View article: Systemische Krebstherapien während der onkologischen Rehabilitation
Systemische Krebstherapien während der onkologischen Rehabilitation Open
View article: Sarcopenia: A Time for Action. An SCWD Position Paper
Sarcopenia: A Time for Action. An SCWD Position Paper Open
The term sarcopenia was introduced in 1988. The original definition was a “muscle loss” of the appendicular muscle mass in the older people as measured by dual energy x‐ray absorptiometry (DXA). In 2010, the definition was altered to be lo…
View article: Meaning in life and quality of life: comparison between palliative care patients and a representative sample of the Swiss population
Meaning in life and quality of life: comparison between palliative care patients and a representative sample of the Swiss population Open
Background and objectives Existential areas, and in particular the concept of meaning in life, represent a key topic in palliative care. The aims of this study are to explore (i) the differences in perceived meaning in life (MIL) and in th…
View article: A prospective study examining cachexia predictors in patients with incurable cancer
A prospective study examining cachexia predictors in patients with incurable cancer Open
View article: Orphan disease status of cancer cachexia in the USA and in the European Union: a systematic review
Orphan disease status of cancer cachexia in the USA and in the European Union: a systematic review Open
Background Cachexia has significant impact on the patients' quality of life and prognosis. It is frequently observed in patients with cancer, especially in advanced stages, but prevalence data for the overall population are lacking. Good q…
View article: Prognostic impact of polypharmacy and drug interactions in patients with advanced cancer
Prognostic impact of polypharmacy and drug interactions in patients with advanced cancer Open
View article: Feasibility of early multimodal interventions for elderly patients with advanced pancreatic and non‐small‐cell lung cancer
Feasibility of early multimodal interventions for elderly patients with advanced pancreatic and non‐small‐cell lung cancer Open
Background Combinations of exercise and nutritional interventions might improve the functional prognosis for cachectic cancer patients. However, high attrition and poor compliance with interventions limit their efficacy. We aimed to test t…
View article: Author Correction: Microbial temperature sensitivity and biomass change explain soil carbon loss with warming
Author Correction: Microbial temperature sensitivity and biomass change explain soil carbon loss with warming Open
View article: Nutritional cancer care: Slowly evolving clinical practice reveals regional and professional HCP variability
Nutritional cancer care: Slowly evolving clinical practice reveals regional and professional HCP variability Open
View article: Evolving concurrent integration of oncology and palliative care at an ESMO designated center over a decade
Evolving concurrent integration of oncology and palliative care at an ESMO designated center over a decade Open
Background: Streamlining oncology (Onc) and specialist palliative care (SPC) into integrated patient (pt) care is increasingly a gold standard of optimized cancer care. The ways that integrated Onc/SPC manifests in clinical practice may ch…