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View article: New-Onset Diabetes After Transplantation in Renal Recipients: A Pilot Comparative Study of Immediate vs. Extended-Release Tacrolimus Formulation
New-Onset Diabetes After Transplantation in Renal Recipients: A Pilot Comparative Study of Immediate vs. Extended-Release Tacrolimus Formulation Open
Tacrolimus is frequently used in immunosuppressive therapy in renal transplant patients and is characterized by high toxicity, a low therapeutic index, and great individual variability. For these reasons, correct dosing is important to ens…
View article: Electrochemical Nanostructured Aptasensor for Direct Detection of Glycated Hemoglobin
Electrochemical Nanostructured Aptasensor for Direct Detection of Glycated Hemoglobin Open
Glycated hemoglobin (HbA1c) is an important biomarker applied for the diagnosis, evaluation, and management of diabetes; therefore, its accurate determination is crucial. In this study, an innovative nanoplatform was developed, integrating…
View article: The Paradox of Clean Eating: Neuroactive Dysbiosis and Pesticide Residues in Fruit- and Vegetable-Based Diets
The Paradox of Clean Eating: Neuroactive Dysbiosis and Pesticide Residues in Fruit- and Vegetable-Based Diets Open
(1) Background: Exposure to pesticide residues through food remains a critical issue in public health, especially given their potential cumulative neurotoxic effects. (2) Methods: This study investigated the presence of pesticide residues …
View article: Evaluating the bioactivity of endodontic sealers with respect to their thermo-nanomechanical properties
Evaluating the bioactivity of endodontic sealers with respect to their thermo-nanomechanical properties Open
Physico-chemical and mechanical features of endodontic sealers are essential functional properties involved in their sealing ability, osteoconductivity, and biocompatibility. Four different root canal sealers (Ceraseal, MTA Fillapex, AH Pl…
View article: Determination of the Bioactive Compounds from Echinacea purpurea (L.) Moench Leaves Extracts in Correlation with the Antimicrobial Activity and the In Vitro Wound Healing Potential
Determination of the Bioactive Compounds from Echinacea purpurea (L.) Moench Leaves Extracts in Correlation with the Antimicrobial Activity and the In Vitro Wound Healing Potential Open
This study aimed at the relationship between antioxidant capacity, antimicrobial activity, and in vitro evaluation of the wound healing effect of the extract obtained from Echinaceae purpureae folium (EPF). This study’s objective was to as…
View article: Novel Liposomal Formulation with Azelaic Acid: Preparation, Characterization, and Evaluation of Biological Properties
Novel Liposomal Formulation with Azelaic Acid: Preparation, Characterization, and Evaluation of Biological Properties Open
Azelaic acid (AA), as a natural product, was proven to be effective in targeting multiple causes of acne and related dermatological conditions, as it is well tolerated using different classical formulations (gel, cream, etc.). However, its…
View article: Echinacea purpurea (L.) Moench: Biological and Pharmacological Properties. A Review
Echinacea purpurea (L.) Moench: Biological and Pharmacological Properties. A Review Open
Echinacea purpurea (L.) Moench (EP)is a perennial herbaceous flowering plant, commonly known as purple coneflower and it belongs to the Asteraceae family. The Echinacea genus is originally from North America, in the United States, and its …
View article: Metal Nanoparticles and Carbon-Based Nanomaterials for Improved Performances of Electrochemical (Bio)Sensors with Biomedical Applications
Metal Nanoparticles and Carbon-Based Nanomaterials for Improved Performances of Electrochemical (Bio)Sensors with Biomedical Applications Open
Monitoring human health for early detection of disease conditions or health disorders is of major clinical importance for maintaining a healthy life. Sensors are small devices employed for qualitative and quantitative determination of vari…
View article: Carbon Nanotubes for Improved Performances of Endodontic Sealer
Carbon Nanotubes for Improved Performances of Endodontic Sealer Open
In order to overcome the limitations of current endodontic sealers, especially against resistant bacteria, recent developments in the field of nanotechnology have proved the necessity to reconsider the composition and physico-chemical prop…
View article: Efficiency of antiviral treatment in COVID‑19
Efficiency of antiviral treatment in COVID‑19 Open
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is responsible for generating a global effort to discover urgent therapeutic solutions to limit the human damage caused by COVID-19. In the period of April to June 2…
View article: Electrochemical Methods for Evaluation of Antioxidant Properties of Propolis Extract Incorporated in Chitosan Nanoparticles
Electrochemical Methods for Evaluation of Antioxidant Properties of Propolis Extract Incorporated in Chitosan Nanoparticles Open
The main purpose of our study was to demonstrate the antioxidant properties of novel propolis nano-formulation, incorporated in spherical chitosan nanoparticles. The electrochemical methods (cyclic voltammetry and differential pulse voltam…
View article: Nanomaterials for Diagnosis and Treatment of Brain Cancer: Recent Updates
Nanomaterials for Diagnosis and Treatment of Brain Cancer: Recent Updates Open
Brain tumors, especially glioblastoma, remain the most aggressive form of all the cancers because of inefficient diagnosis and profiling. Nanostructures, such as metallic nanostructures, silica nano-vehicles, quantum dots, lipid nanopartic…
View article: Aspects Regarding the Relationship Between the Stability of Six Magnesium Compounds and their Cellular Uptake in Mice
Aspects Regarding the Relationship Between the Stability of Six Magnesium Compounds and their Cellular Uptake in Mice Open
This research establishes the relationship between the influence of the stability of 6 magnesium compounds on their cellular uptake and focuses on the comparation between them, finding out which is the magnesium compound with the best bioa…
View article: Interactions between leptin and insulin resistance in patients with prediabetes, with and without NAFLD
Interactions between leptin and insulin resistance in patients with prediabetes, with and without NAFLD Open
This study explored the link between insulin sensitivity, insulin resistance and leptinaemia in people with prediabetes with and without non-alcoholic fatty liver disease (NAFLD). A total of 143 prediabetes patients were evaluated in the s…
View article: Innovative Method of Treating Sintered Metal Powders Surfaces with Optical Radiation Pulses, Using Gas-Discharge Lamp
Innovative Method of Treating Sintered Metal Powders Surfaces with Optical Radiation Pulses, Using Gas-Discharge Lamp Open
The research conducted in the present paper is part of a comprehensive study to innovate a method of surface treatment for some metallic powder materials with alternative energy sources to lasers and electron beams (i.e. with gas-discharge…
View article: Determination of the Total Polyphenols Content and Antioxidant Activity of Echinacea Purpurea Extracts Using Newly Manufactured Glassy Carbon Electrodes Modified with Carbon Nanotubes
Determination of the Total Polyphenols Content and Antioxidant Activity of Echinacea Purpurea Extracts Using Newly Manufactured Glassy Carbon Electrodes Modified with Carbon Nanotubes Open
A sensitive electrochemical method was used for the determination of the total phenolic content and antioxidant activity of Echinacea purpurea extracts. In this study, 3 glassy carbon electrodes (GCE) were used: one unmodified and the othe…