Explanipedia

Comparative assessment of Texas horned lizard (Phrynosoma cornutum) gut microbiome diversity and composition throughout transition from captivity to wild Open

Cameron R. Forehand, Sierra N. Smith, Forrest H. Nielsen, Benjamin U. Bauer, Jessa L. Watters , et al. · 2025

Microbiomes play a key role in the health of animal hosts. To improve conservation translocation programs like headstarting, it is necessary to consider how the structure of these programs impact the host-associated microbiome. Bringing an…

The Role of Dietary Magnesium in Cardiovascular Disease Open

Forrest H. Nielsen · 2024

In the past 20 years, a large number of epidemiological studies, randomized controlled trials, and meta-analyses have found an inverse relationship between magnesium intake or serum magnesium and cardiovascular disease, indicating that low…

An Environmentally Compatible and Less Costly (Greener) Microwave Digestion Method of Bone Samples Using Dilute Nitric Acid for Analysis by ICP-MS Open

Derek D. Bussan, Forrest H. Nielsen, Chris Douvris, Brett Kelzenberg, Allison Grimestad , et al. · 2024

An environmentally compatible and less costly (greener) analytical method for the digestion of bone meal samples using microwave-assisted dilute nitric acid (HNO3) was developed and optimized. The method, employing a mixture of 1 mL concen…

The Role of Dietary Magnesium in Cardiovascular Disease Open

Forrest H. Nielsen · 2024

In the past 20 years, a large number of epidemiological studies, randomized controlled trials, and meta-analyses have found an inverse relationship between magnesium intake or serum magnesium and cardiovascular disease indicating that a lo…

Dietary Intake of Chromista Oil Alters Hepatic Metabolomic Profile of Mice With Excess Fat Mass Open

Bret Rust, Forrest H. Nielsen, Lin Yan · 2024

Increasing dietary intake of fish oil is frequently recommended for decreasing the risk for cardiovascular diseases and improving metabolic health. We hypothesised that dietary intake of chromista oil (a marine food product and a rich sour…

An Environmentally Compatible and Less Costly (Greener) Microwave Digestion Method of Bone Samples Using Dilute Nitric Acid for Analysis by ICP-MS Open

Derek D. Bussan, Forrest H. Nielsen, Chris Douvris, Brett Kelzenberg, Allison Grimestad , et al. · 2024

An environmentally compatible and less costly (green) analytical method for the digestion of bone meal samples using microwave-assisted dilute nitric acid (HNO₃) was developed and optimized. The method employing a mixture of 1 m…

Editorial Open

John B. Vincent, Forrest H. Nielsen, Wen‐Hsing Cheng · 2024

Metabolomic Alteration in Adipose Monocyte Chemotactic Protein-1 Deficient Mice Fed a High-Fat Diet Open

Lin Yan, Bret Rust, Sneha Sundaram, Forrest H. Nielsen · 2024

Monocyte chemotactic protein-1 (MCP-1), a small inducible cytokine, is involved in obesity-related chronic disorders. Adipocytes produce MCP-1 that is elevated in obese humans and in rodent models of obesity. This study examined the hepati…

Boric Acid Alleviates Periodontal Inflammation Induced by IL-1β in Human Gingival Fibroblasts Open

Şerife Buket Bozkurt, Sema S. Hakkı, Forrest H. Nielsen · 2023

Boric acid (BA) has been found to have therapeutic effects on periodontal disease through beneficially affecting antibacterial, anti-viral, and anti-inflammatory actions. Thus, a study was conducted to determine the effect of BA on cell vi…

Perspective: Call for Re-evaluation of the Tolerable Upper Intake Level for Magnesium Supplementation in Adults Open

Rebecca B. Costello, Aaron J. Rosanoff, Forrest H. Nielsen, Christina West · 2023

P11-017-23 Re-Evaluation of the Tolerable Upper Intake Level for Magnesium Supplements Open

Rebecca B. Costello, Aaron J. Rosanoff, Forrest H. Nielsen, Christina West · 2023

Voluntary running of defined distances alters bone microstructure in C57BL/6 mice fed a high-fat diet Open

Lin Yan, Forrest H. Nielsen, Sneha Sundaram, Jay Cao · 2021

Obesity increases the risk for pathological conditions such as bone loss. On the other hand, physical exercise reduces body adiposity. To test the hypothesis that physical activity improves bone quality, we evaluated voluntary running of d…

[The magnesium global network (MaGNet) to promote research on magnesium in diseases focusing on covid-19]. Open

Federica I. Wolf, Jeanette A.M. Maier, Aaron J. Rosanoff, Mario Barbagallo, Shadi Baniasadi , et al. · 2021

When the current SARS-CoV-2 pandemic began in early 2020, the global magnesium researcher community came together and noted the striking similarities between COVID-19 risk factors and conditions associated with magnesium deficit state in h…

Nickel Open

Forrest H. Nielsen · 2020

Boron Open

Forrest H. Nielsen, Curtiss D Eckhert · 2019

Editorial Open

Forrest H. Nielsen · 2019

Effects of Nutritional Deficiency of Boron on the Bones of the Appendicular Skeleton of Mice Open

Alejandro A. Gorustovich, Forrest H. Nielsen · 2018

90th Anniversary Commentary: The AIN-93 Purified Diets for Laboratory Rodents—The Development of a Landmark Article in The Journal of Nutrition and Its Impact on Health and Disease Research Using Rodent Models Open

Forrest H. Nielsen · 2018

The History and Future of Dietary Guidance in America Open

Lisa Jahns, Wendy Davis-Shaw, Alice H. Lichtenstein, Suzanne P. Murphy, Zach Conrad , et al. · 2018

Magnesium deficiency and increased inflammation: current perspectives Open

Forrest H. Nielsen · 2018

Animal studies have shown that magnesium deficiency induces an inflammatory response that results in leukocyte and macrophage activation, release of inflammatory cytokines and acute-phase proteins, and excessive production of free radicals…

Interpreting magnesium status to enhance clinical care Open

Rebecca B. Costello, Forrest H. Nielsen · 2017

The combined determination of serum Mg concentration, 24-h urinary Mg excretion, and dietary Mg intake is currently the most practical method to obtain a sound assessment of Mg status. The strong correlations of Mg deficiency with increase…

Monocyte chemotactic protein-1 deficiency attenuates and high-fat diet exacerbates bone loss in mice with Lewis lung carcinoma Open

Lin Yan, Forrest H. Nielsen, Sneha Sundaram, Jay Cao · 2017

Bone loss occurs in obesity and cancer-associated complications including wasting. This study determined whether a high-fat diet and a deficiency in monocyte chemotactic protein-1 (MCP-1) altered bone structural defects in male C57BL/6 mic…

Perspective: The Case for an Evidence-Based Reference Interval for Serum Magnesium: The Time Has Come Open

Rebecca B. Costello, Ronald J. Elin, Aaron J. Rosanoff, Taylor C. Wallace, Fernando Guerrero‐Romero , et al. · 2016

Guidance for the determination of status indicators and dietary requirements for magnesium Open

Forrest H. Nielsen · 2016

Balance data obtained since 1997 indicate that the Estimated Average Requirement and Recommended Dietary Allowance for magnesium should be 175 and 250 mg/d, respectively, for 70 kg healthy individuals, and increase or decrease based on bod…

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