Fouad Hassouna
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View article: S6K1 phosphorylates Cdk1 and MSH6 to regulate DNA repair
S6K1 phosphorylates Cdk1 and MSH6 to regulate DNA repair Open
The mTORC1 substrate, S6 Kinase 1 (S6K1), is involved in the regulation of cell growth, ribosome biogenesis, glucose homeostasis, and adipogenesis. Accumulating evidence has suggested a role for mTORC1 signaling in the DNA damage response.…
View article: Author response: S6K1 phosphorylates Cdk1 and MSH6 to regulate DNA repair
Author response: S6K1 phosphorylates Cdk1 and MSH6 to regulate DNA repair Open
Article Figures and data Abstract Editor's evaluation eLife digest Introduction Results Discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abstract The mTORC…
View article: S6K1 phosphorylates Cdk1 and MSH6 to regulate DNA repair
S6K1 phosphorylates Cdk1 and MSH6 to regulate DNA repair Open
The mTORC1 substrate, S6 Kinase 1 (S6K1), is involved in the regulation of cell growth, ribosome biogenesis, glucose homeostasis and adipogenesis. Accumulating evidence has suggested a role for mTORC1 signaling in the DNA damage response. …
View article: RNA binding of Hfq monomers promotes RelA-mediated hexamerization in a limiting Hfq environment
RNA binding of Hfq monomers promotes RelA-mediated hexamerization in a limiting Hfq environment Open
The RNA chaperone Hfq acting as a hexamer, is a known mediator of post-transcriptional regulation expediting basepairing between small RNAs (sRNAs) and their target mRNAs. However, the intricate details associated with Hfq-RNA biogenesis a…