Chris Frampton
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View article: Do uncemented humeral components perform better than cemented humeral components in reverse total shoulder arthroplasty for acute proximal humerus fracture? A New Zealand Joint Registry Study
Do uncemented humeral components perform better than cemented humeral components in reverse total shoulder arthroplasty for acute proximal humerus fracture? A New Zealand Joint Registry Study Open
View article: Preparing House Officers for Emergencies in a Psychiatric Setting with Simulation-Based Learning
Preparing House Officers for Emergencies in a Psychiatric Setting with Simulation-Based Learning Open
Objective Simulation-based learning replicates real clinical events to provide an interactive learning experience. This allows training doctors to develop skills to manage complex scenarios or emergencies in a safe and containing environme…
View article: Nationwide Implementation of Unguided Cognitive Behavioral Therapy for Adolescent Depression: Observational Study of SPARX
Nationwide Implementation of Unguided Cognitive Behavioral Therapy for Adolescent Depression: Observational Study of SPARX Open
Background Internet-based cognitive behavioral therapy (iCBT) interventions are effective in clinical trials; however, iCBT implementation data are seldom reported. Objective The objective of this study is to evaluate uptake, adherence, an…
View article: Timing of antibacterial prophylaxis and surgical site infection rates in clean orthopaedic and cardiac surgery
Timing of antibacterial prophylaxis and surgical site infection rates in clean orthopaedic and cardiac surgery Open
Background The timing of antibacterial prophylaxis in the hour before incision is unsettled due to inadequate clinical outcome data. The aim of this study was to determine whether the timing of antibacterial prophylaxis in the hour before …
View article: Quality improvement and workplace wellbeing capacity and capability in Aotearoa New Zealand emergency departments. A nationwide mixed methods survey
Quality improvement and workplace wellbeing capacity and capability in Aotearoa New Zealand emergency departments. A nationwide mixed methods survey Open
Background Healthcare workers in emergency departments (EDs) need to function optimally to deliver high-quality healthcare. High levels of burnout negatively impact these workers’ delivery of quality care to their patients. Quality improve…
View article: 8 Timing of surgical antibiotic prophylaxis and surgical site infection rates: timing within the hour before incision may not matter
8 Timing of surgical antibiotic prophylaxis and surgical site infection rates: timing within the hour before incision may not matter Open
Aim The impact of surgical prophylaxis timing within the hour before incision on surgical site infection (SSI) rates is undefined. We analysed the SSI rates for timing within the hour before incision to see if there was evidence for an opt…
View article: 23 Duration of surgical antibiotic prophylaxis after cardiac surgery: 24 hours is sufficient
23 Duration of surgical antibiotic prophylaxis after cardiac surgery: 24 hours is sufficient Open
Aim Up to 48 h post-operation prophylaxis is recommended following cardiac surgery. We analysed the surgical site infection (SSI) rates following 24- or 48-h prophylaxis to see if 24 h was inferior to 48-h duration. Method We analysed the …
View article: Antibiotic-Loaded Bone Cement and Risk of Infection After Knee Arthroplasty in High-Risk Patients
Antibiotic-Loaded Bone Cement and Risk of Infection After Knee Arthroplasty in High-Risk Patients Open
Background: The use of antibiotic-loaded bone cement (ALBC) in primary total knee arthroplasty (TKA) is debated. Some argue that ALBC might only be justified in high-risk patients. This study assessed the effectiveness of ALBC vs. plain bo…
View article: POS1231 COLCHICINE CONCENTRATIONS AND RELATIONSHIP WITH COLCHICINE EFFICACY AND ADVERSE EVENTS; POST-HOC ANALYSIS OF A RANDOMISED CLINICAL TRIAL OF COLCHICINE FOR GOUT FLARE PROPHYLAXIS
POS1231 COLCHICINE CONCENTRATIONS AND RELATIONSHIP WITH COLCHICINE EFFICACY AND ADVERSE EVENTS; POST-HOC ANALYSIS OF A RANDOMISED CLINICAL TRIAL OF COLCHICINE FOR GOUT FLARE PROPHYLAXIS Open
View article: Compounding Prevalence of Inflammatory Bowel Disease in a 2024 Population‐Based Study From Canterbury, New Zealand
Compounding Prevalence of Inflammatory Bowel Disease in a 2024 Population‐Based Study From Canterbury, New Zealand Open
Background and Aim The epidemiological patterns of inflammatory bowel disease (IBD) can give insights into disease etiology and health system burden. This study aimed to measure the population‐based prevalence in Canterbury and consider th…
View article: Myeloperoxidase Enzyme Activity in Feces Reflects Endoscopic Severity in Inflammatory Bowel Disease
Myeloperoxidase Enzyme Activity in Feces Reflects Endoscopic Severity in Inflammatory Bowel Disease Open
Background Concentrations of the neutrophil protein myeloperoxidase are elevated in the feces of individuals with endoscopically active inflammatory bowel disease (IBD). Its enzyme activity could give an immediate readout of endoscopic inf…
View article: High Flow Nasal Oxygen and Low Flow Oxygen Are Equally Effective in Providing Oxygenation During Bronchoscopy Under Conscious Sedation: A Randomised Controlled Trial
High Flow Nasal Oxygen and Low Flow Oxygen Are Equally Effective in Providing Oxygenation During Bronchoscopy Under Conscious Sedation: A Randomised Controlled Trial Open
Background and Objective Oxygen desaturations and hypoxaemia are common during bronchoscopy despite the use of conventional low flow oxygen (LFO). Some researchers suggest high flow nasal oxygen (HFNO) may improve oxygenation in patients u…
View article: Plasma Calprotectin and Myeloperoxidase as Biomarkers in Inflammatory Bowel Disease
Plasma Calprotectin and Myeloperoxidase as Biomarkers in Inflammatory Bowel Disease Open
Background Inflammatory bowel disease (IBD) is a relapsing-remitting illness requiring proactive monitoring of gut inflammation. We aimed to determine the correlations of plasma myeloperoxidase (pMPO) and calprotectin (pCal), two neutrophi…
View article: Symptom Overlap Between Depression and Borderline Personality Disorder: A Network Analysis
Symptom Overlap Between Depression and Borderline Personality Disorder: A Network Analysis Open
Major depression (MD) is a serious mental health disorder projected to become the leading cause of global disability by 2030. Borderline personality disorder (BPD) frequently co‐occurs with MD. Individuals with both conditions often experi…
View article: VEGF-A cis-located SNPs on human chromosome 6 associated with VEGF-A plasma levels and survival in a coronary disease cohort
VEGF-A cis-located SNPs on human chromosome 6 associated with VEGF-A plasma levels and survival in a coronary disease cohort Open
View article: Clinical features and mortality outcomes of people transferred from prison to forensic mental health units: a nationwide 14-year retrospective cohort study
Clinical features and mortality outcomes of people transferred from prison to forensic mental health units: a nationwide 14-year retrospective cohort study Open
View article: Comparative analysis of suture choice in open bilateral carpal tunnel surgery: a randomized controlled trial
Comparative analysis of suture choice in open bilateral carpal tunnel surgery: a randomized controlled trial Open
Objective This randomized controlled trial (RCT) compared outcomes of absorbable and non‐absorbable sutures for skin closure in open carpal tunnel decompression. Methods Patients diagnosed with bilateral carpal tunnel syndrome proceeding t…
View article: Investigation of a broad‐spectrum micronutrient formulation as a possible precipitant of pharmacokinetic micronutrient–drug interactions
Investigation of a broad‐spectrum micronutrient formulation as a possible precipitant of pharmacokinetic micronutrient–drug interactions Open
Aims Daily broad‐spectrum micronutrients are being used by the general public and formulations are receiving research interest in mental health settings. Despite concerns about combining medicines and broad‐spectrum micronutrients in menta…
View article: Obesity has no significant association with revision rate and functional outcomes following total shoulder arthroplasty—results from the New Zealand National Joint Registry
Obesity has no significant association with revision rate and functional outcomes following total shoulder arthroplasty—results from the New Zealand National Joint Registry Open
View article: A 10-year comparative analysis of the 2 most common reverse total shoulder arthroplasty implants (Delta Xtend and SMR) in the New Zealand Joint Registry
A 10-year comparative analysis of the 2 most common reverse total shoulder arthroplasty implants (Delta Xtend and SMR) in the New Zealand Joint Registry Open
Overall, we found that the Delta Xtend cemented group had more than a 2-fold risk of revision compared with Delta Xtend cementless and SMR cementless groups, whereas there was no difference in revision risk between the Delta Xtend and SMR …
View article: Relationship Between Gout Flare States and Patient‐Reported Outcomes After Allopurinol Initiation
Relationship Between Gout Flare States and Patient‐Reported Outcomes After Allopurinol Initiation Open
Objective Gout flares are the most important clinical feature of the disease. A hypothetical maximum flare occurrence in the preceding six months has been suggested to be no flares for a patient‐acceptable symptom state (PASS) and only one…
View article: Study Protocol for a Randomized Controlled Trial Investigating the Effects of the Daily Consumption of Ruminant Milk on Digestive Comfort and Nutrition in Older Women: The YUMMI Study
Study Protocol for a Randomized Controlled Trial Investigating the Effects of the Daily Consumption of Ruminant Milk on Digestive Comfort and Nutrition in Older Women: The YUMMI Study Open
Background: Age-related changes can lead to dietary insufficiency in older adults. The inclusion of high-quality, nutrient-dense foods such as ruminant milks can significantly improve health outcomes. However, many older adults worldwide d…
View article: Number of Doses of Systemic Antibiotic Prophylaxis May Be Reduced in Cemented Primary Knee Arthroplasty Irrespective of Use of Antibiotic in the Cement: A Multiregistry-Based Meta-Analysis
Number of Doses of Systemic Antibiotic Prophylaxis May Be Reduced in Cemented Primary Knee Arthroplasty Irrespective of Use of Antibiotic in the Cement: A Multiregistry-Based Meta-Analysis Open
Background: The use of systemic antibiotic prophylaxis (SAP) and antibiotic-loaded bone cement (ALBC) is the accepted practice to reduce the risk of periprosthetic joint infection (PJI) in primary total knee arthroplasty (pTKA). However, p…
View article: Ten‐year outcomes of a prospective population‐based incidence cohort of inflammatory bowel disease patients from Canterbury, New Zealand
Ten‐year outcomes of a prospective population‐based incidence cohort of inflammatory bowel disease patients from Canterbury, New Zealand Open
Background and Aim Inflammatory bowel disease (IBD) is a progressive condition where ongoing inflammation in the gastrointestinal tract can lead to complications such as strictures, and fistulae. The long‐term outcomes of newly diagnosed p…
View article: Investigating the impact of a multicomponent positive participatory organisational intervention on burnout in New Zealand emergency department staff: a prospective, multisite, before and after, mixed methods study
Investigating the impact of a multicomponent positive participatory organisational intervention on burnout in New Zealand emergency department staff: a prospective, multisite, before and after, mixed methods study Open
Introduction The well-being of healthcare workers (HCWs) is critical to providing excellent care. Recent evidence concerns the well-being of emergency department (ED) HCWs in New Zealand, with high levels of burnout found in a 2020 survey.…
View article: O056 Workplace fatigue in the New Zealand healthcare workforce: A snapshot survey
O056 Workplace fatigue in the New Zealand healthcare workforce: A snapshot survey Open
Introduction A growing body of research has highlighted that workplace fatigue is associated with decreased patient safety, increased healthcare costs and adverse health and safety consequences for healthcare workers. Methods All workers i…
View article: Compulsory Community Treatment Orders and health outcomes for Māori in New Zealand
Compulsory Community Treatment Orders and health outcomes for Māori in New Zealand Open
Background: We have previously analysed outcomes for all community treatment orders commenced during a 10-year period in New Zealand. Given Te Tiriti O Waitangi obligations to scrutinise health and consider equity for Māori, we completed t…
View article: Exclusive Enteral Nutrition as Induction Therapy for Paediatric Crohn Disease – Efficacy, Outcomes and Predictors of Response over a Ten-Year Period
Exclusive Enteral Nutrition as Induction Therapy for Paediatric Crohn Disease – Efficacy, Outcomes and Predictors of Response over a Ten-Year Period Open
Background: Exclusive enteral nutrition (EEN) is the recommended first-line induction therapy for pediatric patients with active luminal Crohn’s disease (CD). The primary aim of this retrospective study was to ascertain the efficacy of EEN…
View article: Outcomes Related to New Persistent Opioid Use After Surgery or Trauma
Outcomes Related to New Persistent Opioid Use After Surgery or Trauma Open
Objectives: To evaluate the impact of persistent opioid use (POU) following surgery or trauma on health outcomes using linked data. Background: Surgery and trauma can lead to POU, characterized by continuous opioid consumption following ho…
View article: Association of rare and common genetic variants in <i>MOCOS</i> with inadequate response to allopurinol
Association of rare and common genetic variants in <i>MOCOS</i> with inadequate response to allopurinol Open
Objectives The minor allele of the common rs2231142 ABCG2 variant predicts inadequate response to allopurinol urate lowering therapy. We hypothesize that additional variants in genes encoding urate transporters and allopurinol-to-oxypurino…