Frances Chu
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View article: Implementation science: why should we care?
Implementation science: why should we care? Open
There is a 17-year gap between the publication of research which proves an intervention is efficacious and effective and the implementation of that same intervention into practice [1]. In behavioral health, only 14% of successful intervent…
View article: A scoping review of new implementations of interprofessional bedside rounding models to improve teamwork, care, and outcomes in hospitals
A scoping review of new implementations of interprofessional bedside rounding models to improve teamwork, care, and outcomes in hospitals Open
Poor communication within healthcare teams occurs commonly, contributing to inefficiency, medical errors, conflict, and other adverse outcomes. Interprofessional bedside rounds (IBR) are a promising model that brings two or more health pro…
View article: Is Malignancies Related Gastrointestinal Bleeding Safe for Cardiopulmonary Bypass Surgery? - A Case-control Study
Is Malignancies Related Gastrointestinal Bleeding Safe for Cardiopulmonary Bypass Surgery? - A Case-control Study Open
The aggravation risk of malignancies related gastrointestinal bleeding (M-GIB) after cardiac surgery under cardiopulmonary bypass (CPB) was unknown, our study aimed to demonstrate the risk to help clinical decision making under this compli…
View article: Digital health interventions to support family caregivers: An updated systematic review
Digital health interventions to support family caregivers: An updated systematic review Open
Objective Chronic diseases are the leading causes of death and disability in the U.S., and disease management largely falls onto patients’ family caregivers. The long-term burden and stress of caregiving negatively impact caregivers’ well-…
View article: Virtual Intervention for Caregivers of Persons With Lewy Body Dementia: Pilot Quasi-Experimental Single-Arm Study
Virtual Intervention for Caregivers of Persons With Lewy Body Dementia: Pilot Quasi-Experimental Single-Arm Study Open
Background Compared to other types of dementia, family caregivers of people with Lewy body dementia (LBD) report higher stress levels and more severe depressive symptoms. Although several digital support interventions for caregivers of per…
View article: Behavioral Change Factors and Retention in Web-Based Interventions for Informal Caregivers of People Living With Dementia: Scoping Review
Behavioral Change Factors and Retention in Web-Based Interventions for Informal Caregivers of People Living With Dementia: Scoping Review Open
Background Web-based interventions aimed at supporting informal caregivers of people living with dementia have the potential to improve caregivers’ well-being and psychological health. However, few interventions are widely implemented for …
View article: Behavioral Change Factors and Retention in Web-Based Interventions for Informal Caregivers of People Living With Dementia: Scoping Review (Preprint)
Behavioral Change Factors and Retention in Web-Based Interventions for Informal Caregivers of People Living With Dementia: Scoping Review (Preprint) Open
BACKGROUND Web-based interventions aimed at supporting informal caregivers of people living with dementia have the potential to improve caregivers’ well-being and psychological health. However, few interventions are widely implemented for…
View article: The C terminus of the mycobacterium ESX-1 secretion system substrate ESAT-6 is required for phagosomal membrane damage and virulence
The C terminus of the mycobacterium ESX-1 secretion system substrate ESAT-6 is required for phagosomal membrane damage and virulence Open
Significance Tuberculosis (TB), an ancient disease of humanity, continues to be a major cause of worldwide death. The causative agent of TB, Mycobacterium tuberculosis , and its close pathogenic relative Mycobacterium marinum , initially i…
View article: Pilot Evaluation of a Virtual Intervention for Caregivers of Persons with Lewy Body Dementia (LBD) (Preprint)
Pilot Evaluation of a Virtual Intervention for Caregivers of Persons with Lewy Body Dementia (LBD) (Preprint) Open
BACKGROUND Compared to other types of dementia, family caregivers of people with LBD report higher stress and more severe depressive symptoms. OBJECTIVE We performed a pilot evaluation of a digital intervention designed to help caregive…
View article: Patient Digital Health Technologies to Support Primary Care Across Clinical Contexts: Survey of Primary Care Providers, Behavioral Health Consultants, and Nurses
Patient Digital Health Technologies to Support Primary Care Across Clinical Contexts: Survey of Primary Care Providers, Behavioral Health Consultants, and Nurses Open
Background The acceptance of digital health technologies to support patient care for various clinical conditions among primary care providers and staff has not been explored. Objective The purpose of this study was to explore the extent of…
View article: The C terminus of the mycobacterium ESX-1 secretion system substrate ESAT-6 is required for phagosomal membrane damage and virulence
The C terminus of the mycobacterium ESX-1 secretion system substrate ESAT-6 is required for phagosomal membrane damage and virulence Open
Mycobacterium tuberculosis and its close relative Mycobacterium marinum infect macrophages and induce the formation of granulomas, organized macrophage-rich immune aggregates. These mycobacterial pathogens can accelerate and co-opt granulo…
View article: An Online Community Intervention for Older Persons with Pre-Frailty and Frailty: Pilot Studies
An Online Community Intervention for Older Persons with Pre-Frailty and Frailty: Pilot Studies Open
Online community interventions can support self-management in older populations but have rarely targeted symptomology of pre-frailty and frailty. To support older adults’ pre-frailty/frailty symptom management, we iteratively refined an ap…
View article: A scoping review of new implementations of interprofessional bedside rounding models to improve teamwork, care, and outcomes in hospitals
A scoping review of new implementations of interprofessional bedside rounding models to improve teamwork, care, and outcomes in hospitals Open
Poor communication within healthcare teams occurs commonly, contributing to inefficiency, medical errors, conflict, and other adverse outcomes. Interprofessional bedside rounds (IBR) are a promising model that brings two or more health pro…
View article: Telemental Health After COVID-19
Telemental Health After COVID-19 Open
To the Editor: Given the rapid adoption of telemental health (TMH) during the COVID-19 pandemic, we were enthusiastic to read Zimmerman and colleagues' 1 recent work.They found significant clinical and functional improvements among 207 par…
View article: Patient Digital Health Technologies to Support Primary Care Across Clinical Contexts: Survey of Primary Care Providers, Behavioral Health Consultants, and Nurses (Preprint)
Patient Digital Health Technologies to Support Primary Care Across Clinical Contexts: Survey of Primary Care Providers, Behavioral Health Consultants, and Nurses (Preprint) Open
BACKGROUND The acceptance of digital health technologies to support patient care for various clinical conditions among primary care providers and staff has not been explored. OBJECTIVE The purpose of this study was to explore the extent…
View article: 16506 Recognizing Interdisciplinary Collaborative Research in Promotion and Tenure Processes
16506 Recognizing Interdisciplinary Collaborative Research in Promotion and Tenure Processes Open
IMPACT: Recognizing Interdisciplinary Collaborative Research in Promotion and Tenure Processes OBJECTIVES/GOALS: Academic institutions have traditionally focused on individual achievements for promotion. We present our effort on identifyin…
View article: Promoting Problem Solving About Health Management: A Mixed-Methods Pilot Evaluation of a Digital Health Intervention for Older Adults With Pre-Frailty and Frailty
Promoting Problem Solving About Health Management: A Mixed-Methods Pilot Evaluation of a Digital Health Intervention for Older Adults With Pre-Frailty and Frailty Open
Background: There is a need for interventions to promote health management of older adults with pre-frailty and frailty. Technology poses promising solutions, but questions exist about effective delivery. Objectives: We present the results…
View article: Association of Alternative Payment and Delivery Models With Outcomes for Mental Health and Substance Use Disorders
Association of Alternative Payment and Delivery Models With Outcomes for Mental Health and Substance Use Disorders Open
In this study, APMs were associated with improvements in process-of-care outcomes, reductions in MH/SUD utilization, and decreases in spending. However, these findings cannot fully substitute for assessments of clinical outcomes, which hav…
View article: USABILITY OF AN ONLINE DISCUSSION PLATFORM: DEVELOPMENT OF A CODING SCHEME
USABILITY OF AN ONLINE DISCUSSION PLATFORM: DEVELOPMENT OF A CODING SCHEME Open
Online discussion platforms have the potential to support or even improve older adults’ well-being. Nonetheless, potential health benefits are often shaped by the usability of such platforms. Improving usability is imperative to maximize t…
View article: OUTCOMES MEASUREMENT IN EARLY-STAGE MEMORY LOSS INTERVENTIONS: A SCOPING REVIEW
OUTCOMES MEASUREMENT IN EARLY-STAGE MEMORY LOSS INTERVENTIONS: A SCOPING REVIEW Open
Psychosocial and psychoeducational groups are widely recommended for individuals with early stage Alzheimer’s disease and related dementias (ADRD). However, measurement challenges have hindered researchers’ efforts to demonstrate the effic…
View article: VIRTUAL ONLINE COMMUNITIES FOR AGING LIFE EXPERIENCE (VOCALE) APPROACH: PILOT STUDIES
VIRTUAL ONLINE COMMUNITIES FOR AGING LIFE EXPERIENCE (VOCALE) APPROACH: PILOT STUDIES Open
Emerging evidence suggests behavioral strategies focusing on symptom management can reduce frailty symptoms and improve quality of life. Unfortunately, these interventions are rarely scalable for implementation in geriatric care. Contempor…
View article: Oxygen-limited metabolism in the methanotroph <i>Methylomicrobium buryatense</i> 5GB1C
Oxygen-limited metabolism in the methanotroph <i>Methylomicrobium buryatense</i> 5GB1C Open
The bacteria that grow on methane aerobically (methanotrophs) support populations of non-methanotrophs in the natural environment by excreting methane-derived carbon. One group of excreted compounds are short-chain organic acids, generated…
View article: A scoping review of epidemiologic risk factors for pediatric obesity: Implications for future childhood obesity and dental caries prevention research
A scoping review of epidemiologic risk factors for pediatric obesity: Implications for future childhood obesity and dental caries prevention research Open
Research Questions What are the non‐modifiable (socioeconomic, genetic) and modifiable factors (physical activity, dietary behaviors) related to childhood (under age 12) obesity? How can this knowledge be applied to oral health professiona…
View article: Mycobacterial ESX-1 secretion system mediates host cell lysis through bacterium contact-dependent gross membrane disruptions
Mycobacterial ESX-1 secretion system mediates host cell lysis through bacterium contact-dependent gross membrane disruptions Open
Significance Secreted pore-forming toxins are a common feature of bacterial virulence. Mycobacterium tuberculosis , the agent of human tuberculosis, has been reported to possess a pore-forming toxin called 6 kDa early secretory antigenic t…
View article: MxaY regulates the lanthanide-mediated methanol dehydrogenase switch in <i>Methylomicrobium buryatense</i>
MxaY regulates the lanthanide-mediated methanol dehydrogenase switch in <i>Methylomicrobium buryatense</i> Open
Many methylotrophs, microorganisms that consume carbon compounds lacking carbon–carbon bonds, use two different systems to oxidize methanol for energy production and biomass accumulation. The MxaFI methanol dehydrogenase (MDH) contains cal…