Francesca Di Candia
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View article: Glucometabolic Control and Anti-Transglutaminase Antibodies at Celiac Disease Onset in Type 1 Diabetes Youth
Glucometabolic Control and Anti-Transglutaminase Antibodies at Celiac Disease Onset in Type 1 Diabetes Youth Open
Context Anti-transglutaminase antibodies (anti-TTG IgA) titer is associated with mucosal damage in celiac disease (CD). Objective The primary focus was to correlate anti-TTG IgA titer, HbA1c when CD occurs (HbA1cCD), and Marsh grade in chi…
View article: Are We Ready With Prevention for Type 1 Diabetes?
Are We Ready With Prevention for Type 1 Diabetes? Open
Definitive prevention for type 1 diabetes (T1D) is not yet available, but we are now entering a new era where disease‐modifying therapies are becoming available in T1D to halt disease progression. In this review, we present up‐to‐date know…
View article: Daily Carbohydrate Entries and Glycemic Outcomes following Automated Insulin Delivery System Initiation in Youth with Type 1 Diabetes: A Real-World Multinational Longitudinal Study
Daily Carbohydrate Entries and Glycemic Outcomes following Automated Insulin Delivery System Initiation in Youth with Type 1 Diabetes: A Real-World Multinational Longitudinal Study Open
Objective: To assess the association between daily carbohydrate entries and glycemic outcomes in youth with type 1 diabetes after automated insulin delivery (AID) initiation in real-life settings.Research Design and Methods: In this longit…
View article: Daily Carbohydrate Entries and Glycemic Outcomes following Automated Insulin Delivery System Initiation in Youth with Type 1 Diabetes: A Real-World Multinational Longitudinal Study
Daily Carbohydrate Entries and Glycemic Outcomes following Automated Insulin Delivery System Initiation in Youth with Type 1 Diabetes: A Real-World Multinational Longitudinal Study Open
Objective: To assess the association between daily carbohydrate entries and glycemic outcomes in youth with type 1 diabetes after automated insulin delivery (AID) initiation in real-life settings.Research Design and Methods: In this longit…
View article: Omnipod 5 in children and adolescents with type 1 diabetes: Improved outcomes with fewer boluses
Omnipod 5 in children and adolescents with type 1 diabetes: Improved outcomes with fewer boluses Open
View article: A Systematic Review and Metanalysis on the Impact of Automated Insulin Delivery Systems on Body Mass Index in Youths with Type 1 Diabetes and Potential Predictors
A Systematic Review and Metanalysis on the Impact of Automated Insulin Delivery Systems on Body Mass Index in Youths with Type 1 Diabetes and Potential Predictors Open
View article: Development and validation of a novel method for evaluation of multiple islet autoantibodies in dried blood spot using dissociation‐enhanced lanthanide fluorescent immunoassays technology, specific and suitable for paediatric screening programmes
Development and validation of a novel method for evaluation of multiple islet autoantibodies in dried blood spot using dissociation‐enhanced lanthanide fluorescent immunoassays technology, specific and suitable for paediatric screening programmes Open
View article: Future acceptance of automated insulin delivery systems in youths with type 1 diabetes: validation of the Italian artificial pancreas-acceptance measure
Future acceptance of automated insulin delivery systems in youths with type 1 diabetes: validation of the Italian artificial pancreas-acceptance measure Open
Aim The purpose of this study was to develop a questionnaire to examine the future acceptance of Automatic insulin delivery systems (AIDs), their perceived usefulness, ease of use, and trust in the device in subjects with type 1 diabetes (…
View article: Endocrine features of Prader-Willi syndrome: a narrative review focusing on genotype-phenotype correlation
Endocrine features of Prader-Willi syndrome: a narrative review focusing on genotype-phenotype correlation Open
Prader-Willi syndrome (PWS) is a complex genetic disorder caused by three different types of molecular genetic abnormalities. The most common defect is a deletion on the paternal 15q11-q13 chromosome, which is seen in about 60% of individu…
View article: Sustained effectiveness of an advanced hybrid closed loop system in a cohort of children and adolescents with type 1 diabetes: a one-year real-world study
Sustained effectiveness of an advanced hybrid closed loop system in a cohort of children and adolescents with type 1 diabetes: a one-year real-world study Open
Objective. To investigate glucose metrics and identify potential predictors of the achievement of glycemic outcomes in children and adolescents during their first 12 months of MiniMed™ 780G use. Research design and methods. In this multice…
View article: Sustained Effectiveness of an Advanced Hybrid Closed-Loop System in a Cohort of Children and Adolescents With Type 1 Diabetes: A 1-Year Real-World Study
Sustained Effectiveness of an Advanced Hybrid Closed-Loop System in a Cohort of Children and Adolescents With Type 1 Diabetes: A 1-Year Real-World Study Open
OBJECTIVE To investigate glucose metrics and identify potential predictors of the achievement of glycemic outcomes in children and adolescents during their first 12 months of MiniMed 780G use. RESEARCH DESIGN AND METHODS This multicenter, …
View article: Sustained effectiveness of an advanced hybrid closed loop system in a cohort of children and adolescents with type 1 diabetes: a one-year real-world study
Sustained effectiveness of an advanced hybrid closed loop system in a cohort of children and adolescents with type 1 diabetes: a one-year real-world study Open
Objective. To investigate glucose metrics and identify potential predictors of the achievement of glycemic outcomes in children and adolescents during their first 12 months of MiniMed™ 780G use. Research design and methods. In this multice…
View article: Maintaining a gluten-free diet is associated with quality of life in youths with type 1 diabetes and celiac disease
Maintaining a gluten-free diet is associated with quality of life in youths with type 1 diabetes and celiac disease Open
View article: Glucometrics and device satisfaction in children and adolescents with type 1 diabetes using different treatment modalities: A multicenter real-world observational study
Glucometrics and device satisfaction in children and adolescents with type 1 diabetes using different treatment modalities: A multicenter real-world observational study Open
View article: Progression of type 1 diabetes is associated with high levels of soluble PD-1 in islet autoantibody-positive children
Progression of type 1 diabetes is associated with high levels of soluble PD-1 in islet autoantibody-positive children Open
View article: Maintaining the gluten-free diet: The key to improve glycemic metrics in youths with type 1 diabetes and celiac disease
Maintaining the gluten-free diet: The key to improve glycemic metrics in youths with type 1 diabetes and celiac disease Open
Individuals with T1D and CD who maintain GFD presented similar glucose metrics compared to youths with T1D only. Individuals not strictly maintaining GFD presented higher hyperglycemia rates.
View article: An Italian case series' description of thiamine responsive megaloblastic anemia syndrome: importance of early diagnosis and treatment
An Italian case series' description of thiamine responsive megaloblastic anemia syndrome: importance of early diagnosis and treatment Open
Background Individuals with thiamine-responsive megaloblastic anemia (TRMA) mainly manifest macrocytic anemia, sensorineural deafness, ocular complications, and nonautoimmune diabetes. Macrocytic anemia and diabetes may be responsive to hi…
View article: Measures of Patient-Reported Expectations, Acceptance, and Satisfaction Using Automated Insulin Delivery Systems: A Review
Measures of Patient-Reported Expectations, Acceptance, and Satisfaction Using Automated Insulin Delivery Systems: A Review Open
In people with type 1 diabetes, Automated Insulin Delivery (AID) systems adjust insulin delivery in response to sensor glucose data and consist of three components: an insulin pump, a continuous glucose sensor, and an algorithm that determ…
View article: Analysis of Corneal Deformation in Paediatric Patients Affected by Maturity Onset Diabetes of the Young Type 2
Analysis of Corneal Deformation in Paediatric Patients Affected by Maturity Onset Diabetes of the Young Type 2 Open
Background: To evaluate corneal deformation in Maturity Onset Diabetes of the Young type 2 (MODY2), paediatric subjects were analysed using a Scheimpflug-based device. The purpose of this analysis was to find new biomarkers for MODY2 disea…
View article: A systematic review on the impact of commercially available hybrid closed loop systems on psychological outcomes in youths with type 1 diabetes and their parents
A systematic review on the impact of commercially available hybrid closed loop systems on psychological outcomes in youths with type 1 diabetes and their parents Open
Aim To systematically assess the impact of commercially available hybrid closed loop (HCL) systems on psychological outcomes in youths with type 1 diabetes and their parents. Methods We performed a systematic review including studies publi…
View article: Adherence to the Gluten-Free Diet: The Key to Improve Glucose Control in Pediatric Subjects with Type 1 Diabetes and Celiac Disease
Adherence to the Gluten-Free Diet: The Key to Improve Glucose Control in Pediatric Subjects with Type 1 Diabetes and Celiac Disease Open
View article: Glucometrics and Device Satisfaction in Children and Adolescents with Type 1 Diabetes Using Different Treatment Modalities: A Multicenter Real-World Observational Study
Glucometrics and Device Satisfaction in Children and Adolescents with Type 1 Diabetes Using Different Treatment Modalities: A Multicenter Real-World Observational Study Open
View article: Optimal Prandial Timing of Insulin Bolus in Youths with Type 1 Diabetes: A Systematic Review
Optimal Prandial Timing of Insulin Bolus in Youths with Type 1 Diabetes: A Systematic Review Open
The aim of this systematic review was to report the evidence on optimal prandial timing of insulin bolus in youths with type 1 diabetes. A systematic search was performed including studies published in the last 20 years (2002–2022). A PICO…
View article: Uric acid and cardiometabolic risk by gender in youth with type 1 diabetes
Uric acid and cardiometabolic risk by gender in youth with type 1 diabetes Open
View article: Uric acid and cardiometabolic risk profile in youths with type 1 diabetes: sex-related associations
Uric acid and cardiometabolic risk profile in youths with type 1 diabetes: sex-related associations Open
The aim of this study was to investigate the association between uric acid (UA) and cardiometabolic risk factors (CMRFs) by sex in youths with type 1 diabetes (T1D). Retrospective data collected from 1323 youths (5-18 years; 716 boys) with…
View article: Doctor-Patient Relationship in Synchronous/Real-time Video-Consultations and In-Person Visits: An Investigation of the Perceptions of Young People with Type 1 Diabetes and Their Parents During the COVID-19 Pandemic
Doctor-Patient Relationship in Synchronous/Real-time Video-Consultations and In-Person Visits: An Investigation of the Perceptions of Young People with Type 1 Diabetes and Their Parents During the COVID-19 Pandemic Open
View article: RASopathies and hemostatic abnormalities: key role of platelet dysfunction
RASopathies and hemostatic abnormalities: key role of platelet dysfunction Open
Background Bleeding anomalies have been reported in patients affected by Noonan syndrome. No study has been performed in patients with molecularly confirmed RASopathy. We aimed to characterize the frequency and types of bleeding disorders …
View article: Risk of autoimmune diseases in patients with RASopathies: systematic study of humoral and cellular immunity
Risk of autoimmune diseases in patients with RASopathies: systematic study of humoral and cellular immunity Open
View article: An Overview of Hypoglycemia in Children Including a Comprehensive Practical Diagnostic Flowchart for Clinical Use
An Overview of Hypoglycemia in Children Including a Comprehensive Practical Diagnostic Flowchart for Clinical Use Open
Hypoglycemia is the result of defects/impairment in glucose homeostasis. The main etiological causes are metabolic and/or endocrine and/or other congenital disorders. Despite hypoglycemia is one of the most common emergencies in neonatal a…
View article: Clinical heterogeneity of Kabuki syndrome in a cohort of Italian patients and review of the literature
Clinical heterogeneity of Kabuki syndrome in a cohort of Italian patients and review of the literature Open
Kabuki syndrome (KS) is a well-recognized disorder characterized by postnatal growth deficiency, dysmorphic facial features, skeletal anomalies, and intellectual disability. The syndrome is caused by KMT2D gene mutations or less frequently…