Kelly A. Larkin-Kaiser
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View article: New Approach for Making Standard the Development of Biosensing Devices by a Modular Multi-Purpose Design
New Approach for Making Standard the Development of Biosensing Devices by a Modular Multi-Purpose Design Open
The fast widening of biosensing applications, such as healthcare, drug delivery, food, and military industries, is increasing the need for generality and compatibility among different sensors. To address this challenge, we present here an …
View article: Electrochemical detection of different p53 conformations by using nanostructured surfaces
Electrochemical detection of different p53 conformations by using nanostructured surfaces Open
Protein electrochemistry represents a powerful technique for investigating the function and structure of proteins. Currently available biochemical assays provide limited information related to the conformational state of proteins and high …
View article: Quasi-Digital Biosensor-Interface for a Portable Pen to Monitor Anaesthetics Delivery
Quasi-Digital Biosensor-Interface for a Portable Pen to Monitor Anaesthetics Delivery Open
Monitoring of patient response to the anaesthetic drugs is an attractive improvement for achieving a correct balance of sedation level, increasing the chance of success in the right procedure of anaesthesia. Nowadays, there are no commerci…
View article: Wearablc System for Spinal Cord Injury Rehabilitation with Muscle Fatigue Feedback
Wearablc System for Spinal Cord Injury Rehabilitation with Muscle Fatigue Feedback Open
The design, realization and verification of a system for personalized rehabilitation of Spinal Cord Injury (SCI) patients are here presented. It consists of two main parts: (i) one induces in the patient the physiotherapic movement propose…
View article: An IoT Solution for Online Monitoring of Anesthetics in Human Serum Based on an Integrated Fluidic Bioelectronic System
An IoT Solution for Online Monitoring of Anesthetics in Human Serum Based on an Integrated Fluidic Bioelectronic System Open
In this paper, we present the design, the implementation and the validation of a novel Internet of Things (IoT) drug monitoring system for the online continuous and simultaneous detection of two main anesthetics, e.g., propofol and paracet…
View article: Generating Safety Guidance for Medical Injection with Three-Compartment Pharmacokinetics Model
Generating Safety Guidance for Medical Injection with Three-Compartment Pharmacokinetics Model Open
Medical cyber-physical systems are a new trend of software controlled physical systems that are increasingly common in medical domains. With rapid developments in medical science and computer technology, safety verification and simulation …
View article: A Flexible Front-End for Wearable Electrochemical Sensing
A Flexible Front-End for Wearable Electrochemical Sensing Open
This work presents the design and the realization of a flexible front-end circuitry for electrochemical sensing with wearable devices. The hardware combines readout circuitry for amperometric and Open Circuit Potential (OCP) measurements. …
View article: Highly-stable Li+ ion-selective electrodes based on noble metal nanostructured layers as solid-contacts
Highly-stable Li+ ion-selective electrodes based on noble metal nanostructured layers as solid-contacts Open
Nowadays the development of stable and highly efficient Solid-Contact Ion-Selective Electrodes (SC-ISEs) attracts much attention in the research community because of the great expansion of portable analytical devices. In this work, we pres…
View article: Live Demonstration: An IoT Cloud-Based Architecture for Anesthesia Monitoring
Live Demonstration: An IoT Cloud-Based Architecture for Anesthesia Monitoring Open
Medical Internet of Things (IoT) solutions are already paving the way towards the realization of Smart Hospitals. Following this trend, we propose an IoT cloud-based network for anesthesia on-line monitoring. This architecture allows the a…
View article: Performance of Carbon Nano-Scale Allotropes in Detecting Midazolam and Paracetamol in Undiluted Human Serum
Performance of Carbon Nano-Scale Allotropes in Detecting Midazolam and Paracetamol in Undiluted Human Serum Open
Nano-materials are highly exploited to enhance sensing performance of electrochemical electrodes by increasing the electro-active surface area (EASA). In this paper, an analytical calculation of the deposited EASA is presented and experime…
View article: Long‐term Monitoring of Propofol and Fouling Effect on Pencil Graphite Electrodes
Long‐term Monitoring of Propofol and Fouling Effect on Pencil Graphite Electrodes Open
The evaluation of the efficacy of drugs’ action is of crucial importance for preventing adverse effects due to over‐ or under‐dosing. This is especially valuable in the case of propofol, a benchmark anesthetic, since its plasma concentrati…
View article: IoT for Telemedicine Practices enabled by an Android™ Application with Cloud System Integration
IoT for Telemedicine Practices enabled by an Android™ Application with Cloud System Integration Open
Connected medical devices are already paving the way towards the realization of Smart Hospitals where patient care is improved thanks to Internet of Things (IoT) solutions. Following this trend, in this paper we propose an IoT cloud-based …
View article: IoT Bio-Electronic Multi-Panel Device for On-line Monitoring of Anaesthesia Delivery
IoT Bio-Electronic Multi-Panel Device for On-line Monitoring of Anaesthesia Delivery Open
After a failure of "One-Size-Fits-All" approach on traditional treatment of diseases, the age of multi-faceted personalized medicine came into being for tailoring therapy to get the best response in the highest safety margin. Personalized …
View article: Organs-on-chip monitoring: sensors and other strategies
Organs-on-chip monitoring: sensors and other strategies Open
As a paradigm shifting player of tissue engineering, organs-on-chips (OOCs) are considered to hold great potential for future “clinical trials on chip” as well as a step forward to design personalized medicine. Despite all ethical concerns…
View article: Raspberry Pi driven flow-injection system for electrochemical continuous monitoring platforms
Raspberry Pi driven flow-injection system for electrochemical continuous monitoring platforms Open
Nowadays, there is an immense interest regarding new bio-sensing technologies, highlighting the need for effective validation of their capabilities. This necessity is more crucial when examining the proprieties of a sensor for continuous m…
View article: Paradigm-Shifting Players for IoT: Smart-Watches for Intensive Care Monitoring
Paradigm-Shifting Players for IoT: Smart-Watches for Intensive Care Monitoring Open
Wearable devices, e.g. smart-watches, are gaining popularity in many fields and in wellness monitoring too. In this paper we propose an IoT application to alert the medical doctor assigned to a critical unit by using a smart-watch. The wea…
View article: FPGA-based approach for automatic peak detection in cyclic voltammetry
FPGA-based approach for automatic peak detection in cyclic voltammetry Open
An adequate drug dosage is often difficult to be achieved in personalized medicine. Especially for critical application, such as anesthesia. To reach the right dose adjustment, electrochemical biosensors can be used to measure the actual c…
View article: In-Vivo Validation of Fully Implantable Multi-Panel Devices for Remote Monitoring of Metabolism
In-Vivo Validation of Fully Implantable Multi-Panel Devices for Remote Monitoring of Metabolism Open
This paper presents the in-vivo tests on a Fully Implantable Multi-Panel Devices for Remote Monitoring of endogenous and exogenous analytes. To investigate issues on biocompatibility, three different covers have been designed, realized and…
View article: Simultaneous monitoring of anesthetics and therapeutic compounds with a portable multichannel potentiostat
Simultaneous monitoring of anesthetics and therapeutic compounds with a portable multichannel potentiostat Open
As metabolic pathways are highly variable among different patients, then an accurate and continuous monitoring of the personal response to drug treatments is essential especially with critical medications, e.g. anesthetic and anti-cancer c…
View article: Wireless Monitoring of Endogenous and Exogenous Biomolecules on an Android Interface
Wireless Monitoring of Endogenous and Exogenous Biomolecules on an Android Interface Open
Monitoring patients in intensive care units is generally expensive and time consuming. A prompter medical intervention for those critical patients is a key factor for their safety. Therefore, a system that offers immediate visualization of…