Francesca Rotondo
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View article: Diversification of an emerging bacterial plant pathogen; insights into the global spread of Xanthomonas euvesicatoria pv. perforans
Diversification of an emerging bacterial plant pathogen; insights into the global spread of Xanthomonas euvesicatoria pv. perforans Open
Emerging and re-emerging plant diseases continue to present multifarious threats to global food security. Considerable recent efforts are therefore being channeled towards understanding the nature of pathogen emergence, their spread and ev…
View article: Uncovering novel KCC2 regulatory motifs through a comprehensive transposon-based mutant library
Uncovering novel KCC2 regulatory motifs through a comprehensive transposon-based mutant library Open
Introduction The neuron-specific K-Cl cotransporter KCC2 maintains low intracellular chloride levels, which are crucial for fast GABAergic and glycinergic neurotransmission. KCC2 also plays a pivotal role in the development of excitatory g…
View article: First Report of <i>Colletotrichum scovillei</i> Causing Anthracnose Fruit Rot of Pepper in Ohio
First Report of <i>Colletotrichum scovillei</i> Causing Anthracnose Fruit Rot of Pepper in Ohio Open
In August 2019, the Ohio State University Vegetable Pathology laboratory received multiple bell and banana pepper fruits (Capsicum annuum, cvs. unknown) from Columbiana County, Ohio. The grower reported a disease incidence of 100% and seve…
View article: <i>In vitro</i> , <i>in planta,</i> and comparative genomic analyses of <i>Pseudomonas syringae</i> pv. <i>syringae</i> strains of pepper ( <i>Capsicum annuum</i> var. <i>annuum</i> )
<i>In vitro</i> , <i>in planta,</i> and comparative genomic analyses of <i>Pseudomonas syringae</i> pv. <i>syringae</i> strains of pepper ( <i>Capsicum annuum</i> var. <i>annuum</i> ) Open
Pseudomonas syringae pv. syringae ( Pss ) is an emerging phytopathogen that causes Pseudomonas leaf spot (PLS) disease in pepper plants. Pss can cause serious economic damage to pepper production, yet very little is known about the virulen…
View article: Triazole resistance in <i>Aspergillus fumigatu</i> s isolated from a tomato production environment exposed to propiconazole
Triazole resistance in <i>Aspergillus fumigatu</i> s isolated from a tomato production environment exposed to propiconazole Open
The emergence of azole-resistant Aspergillus fumigatus (AR Af ) across the world is an important public health concern. We sought to determine if propiconazole, a demethylase inhibitor (DMI) fungicide, exerted a selective pressure for AR A…
View article: Diversification of an emerging bacterial plant pathogen; insights from the global spread of<i>Xanthomonas euvesicatoria</i>pv.<i>perforans</i>
Diversification of an emerging bacterial plant pathogen; insights from the global spread of<i>Xanthomonas euvesicatoria</i>pv.<i>perforans</i> Open
Emerging and re-emerging plant diseases continue to present multifarious threats to global food security. Considerable recent efforts are therefore being channeled towards understanding the nature of pathogen emergence, their spread and ev…
View article: In vitro evaluation of the carcinogenic potential of perfluorinated chemicals
In vitro evaluation of the carcinogenic potential of perfluorinated chemicals Open
Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) are the major components of long-chain per- and polyfluorinated alkyl substances (PFAS), known for their chemical stability and environmental persistence. Even if PFOA and …
View article: Biopesticides provide inadequate control of three foliar bacterial diseases of tomato transplants
Biopesticides provide inadequate control of three foliar bacterial diseases of tomato transplants Open
There are three important diseases caused by bacterial pathogens affecting tomato foliage on seedlings in the greenhouse and on mature plants in the field: bacterial canker, bacterial spot, and bacterial speck. Their causal agents are seed…
View article: In Hoc Signo Vinces—an Exploratory Study on the Impact of Religion on Violence in Sport
In Hoc Signo Vinces—an Exploratory Study on the Impact of Religion on Violence in Sport Open
Does religion continue to spur violence even in contemporary times? This work aims to shed some light on the relationship between belonging to a given religion and violent behavior. Whereas religions often preach love and caring for others…
View article: Mechanistic Interrogation of Cell Transformation In Vitro: The Transformics Assay as an Exemplar of Oncotransformation
Mechanistic Interrogation of Cell Transformation In Vitro: The Transformics Assay as an Exemplar of Oncotransformation Open
The Transformics Assay is an in vitro test which combines the BALB/c 3T3 Cell Transformation Assay (CTA) with microarray transcriptomics. It has been shown to improve upon the mechanistic understanding of the CTA, helping to identify mecha…
View article: Migration Drives the Replacement of Xanthomonas perforans Races in the Absence of Widely Deployed Resistance
Migration Drives the Replacement of Xanthomonas perforans Races in the Absence of Widely Deployed Resistance Open
Changes in Xanthomonas race and species composition causing bacterial spot of tomato have occurred throughout the world and are often associated with epidemics. Knowledge of bacterial population structure is key for resistance discovery an…
View article: Shifts in <i>Xanthomonas</i> spp. causing bacterial spot in processing tomato in the Midwest of the United States
Shifts in <i>Xanthomonas</i> spp. causing bacterial spot in processing tomato in the Midwest of the United States Open
Bacterial spot (BST) is a highly impactful disease of open-field tomatoes produced in the U.S. Midwest. We combined BST survey data from 2010 to 2013 and 2017 to 2020 from midwestern states to characterize BST-causing Xanthomonas species a…
View article: The Pursuit in Nepal of Native <i>Trichoderma</i> spp. for Plant Disease Biocontrol
The Pursuit in Nepal of Native <i>Trichoderma</i> spp. for Plant Disease Biocontrol Open
The characteristics of 41 native Trichoderma isolates collected from diverse microclimatic domains in Nepal and two Ohio isolates and their efficacy in biocontrol of plant diseases were assessed. Species assignment was based on a maximum l…
View article: Transcriptomics and Cell Transformation Assay: an Integrated Approach to Evaluate the Effects of Low Dose Ionizing Radiation
Transcriptomics and Cell Transformation Assay: an Integrated Approach to Evaluate the Effects of Low Dose Ionizing Radiation Open
Background and aims: Ionizing radiation (IR) are a well-known carcinogenic agent, acting through genotoxic mechanisms. In the last years, great attention has been paid to the effects of IR at low doses and to the non-monotonic dose-respons…
View article: Mechanistic Interrogation of Cell Transformation in Vitro: The Transformics Assay as an Exemplar of Oncotransformation
Mechanistic Interrogation of Cell Transformation in Vitro: The Transformics Assay as an Exemplar of Oncotransformation Open
The rodent-based life-time cancer bioassay is still the basic experimental paradigm to assess the carcinogenic potential of chemicals, with relatively little progress regarding the acceptance of in vitro tests. The Transformics Assay is an…
View article: Evaluation of Agricultural Byproducts and Cover Crops as Anaerobic Soil Disinfestation Carbon Sources for Managing a Soilborne Disease Complex in High Tunnel Tomatoes
Evaluation of Agricultural Byproducts and Cover Crops as Anaerobic Soil Disinfestation Carbon Sources for Managing a Soilborne Disease Complex in High Tunnel Tomatoes Open
Anaerobic soil disinfestation (ASD) is a viable option for disease management in tomato production and reduces damage due to a soilborne disease complex consisting of Pyrenochaeta lycopersici, Colletotrichum coccodes, Verticillium dahliae …
View article: The Secretive Liaison of Particulate Matter and SARS-CoV-2. A Hypothesis and Theory Investigation
The Secretive Liaison of Particulate Matter and SARS-CoV-2. A Hypothesis and Theory Investigation Open
As the novel coronavirus disease sweeps across the world, there is growing speculation on the role that atmospheric factors may have played on the different distribution of SARS-CoV-2, and on the epidemiological characteristics of COVID-19…
View article: Exposure to atmospheric aerosols and Preterm births: a combined approach to analyze this association in a cohort in Northern Italy
Exposure to atmospheric aerosols and Preterm births: a combined approach to analyze this association in a cohort in Northern Italy Open
PDS 76: Source specific outdoor air pollution studies, Exhibition Hall (PDS), Ground floor, August 26, 2019, 4:30 PM - 5:30 PM Background/aims Both scientific and regulatory communities need more comprehensive approaches to fully understan…
View article: The transformics assay: first steps for the development of an integrated approach to investigate the malignant cell transformation in vitro
The transformics assay: first steps for the development of an integrated approach to investigate the malignant cell transformation in vitro Open
The development of alternative methods to animal testing is a priority in the context of regulatory toxicology. Carcinogenesis is a field where the demand for alternative methods is particularly high. The standard rodent carcinogenicity bi…
View article: Contrasting species boundaries between sections Alternaria and Porri of the genus <i>Alternaria</i>
Contrasting species boundaries between sections Alternaria and Porri of the genus <i>Alternaria</i> Open
The fungal genus Alternaria comprises a large number of asexual taxa with diverse ecological, morphological and biological modes ranging from saprophytes to plant pathogens. Understanding the speciation processes affecting asexual fungi is…