Francesco Cavani
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View article: Magnesium and strontium-enriched bioactive glasses: superior biocompatibility and angiogenesis, beyond the gold standard
Magnesium and strontium-enriched bioactive glasses: superior biocompatibility and angiogenesis, beyond the gold standard Open
View article: Quantitative Evaluation of Debris Removal from NiTi Rotary Endodontic Instruments After Different Cleaning Procedures
Quantitative Evaluation of Debris Removal from NiTi Rotary Endodontic Instruments After Different Cleaning Procedures Open
Objectives: Endodontic instruments require thorough decontamination and sterilization before use and reuse to ensure the safety and success of treatments. However, standardized protocols are lacking. This study aimed to quantitatively asse…
View article: In Vitro Evaluation of the Effectiveness and pH Variation of Dental Bleaching Gels and Their Effect on Enamel Surface Roughness
In Vitro Evaluation of the Effectiveness and pH Variation of Dental Bleaching Gels and Their Effect on Enamel Surface Roughness Open
Objectives: Potential adverse effects and pH-related effectiveness of bleaching agents have raised some concerns. The aim of this study was to compare three bleaching agents containing hydrogen peroxide (HP) and carbamide peroxide (CP) in …
View article: Quantitative Assessment of Apically Extruded Debris During Retreatment Procedures Using Three Nickel-Titanium Rotary Systems: An In Vitro Comparative Study
Quantitative Assessment of Apically Extruded Debris During Retreatment Procedures Using Three Nickel-Titanium Rotary Systems: An In Vitro Comparative Study Open
Objectives: Apical extrusion of debris can affect the success of endodontic treatments, and the specific performance of certain retreatment systems has not been studied yet. Therefore, the aim of this in vitro study was to quantitatively a…
View article: Piezosurgery versus Reciprocating Saw: Qualitative Comparison of the Morphology of Cutting Surfaces in Ex Vivo Human Bone
Piezosurgery versus Reciprocating Saw: Qualitative Comparison of the Morphology of Cutting Surfaces in Ex Vivo Human Bone Open
The aim of this study was to morphologically evaluate the differences in the cutting surfaces of bone segments obtained by reciprocating saw (RS) and two piezosurgical devices (Piezosurgery Medical—PM—and Piezosurgery Plus—PP) in ex vivo h…
View article: Specific Subcellular Localization of Phosphoinositide-Specific Phospholipase C enzymes in Different Human Osteosarcoma Cell Lines
Specific Subcellular Localization of Phosphoinositide-Specific Phospholipase C enzymes in Different Human Osteosarcoma Cell Lines Open
The role of signal transduction in cancer progression is well established and actively studied, including in osteosarcoma. The signal transduction pathways involved in the regulation of calcium metabolism are being intensively studied, wit…
View article: Influence of heat treatment on fatigue resistance of two NiTi endodontic files
Influence of heat treatment on fatigue resistance of two NiTi endodontic files Open
OBJECTIVES To evaluate the cyclic, torsional fatigue resistance and phase transformation of two heat-treated and non-heat-treated nickel-titanium reciprocating instruments. MATERIALS AND METHODS Twenty non-heat-treated (Procodile, Komet, B…
View article: Push-out bond strength and SEM fractographical analysis of hollow fibre posts used with self-adhesive resin cement: a pilot study
Push-out bond strength and SEM fractographical analysis of hollow fibre posts used with self-adhesive resin cement: a pilot study Open
View article: In‐vivo evaluations of bone regenerative potential of two novel bioactive glasses
In‐vivo evaluations of bone regenerative potential of two novel bioactive glasses Open
Due to the aging of population, materials able to repair damaged tissues are needed. Among others, bioactive glasses (BGs) have attracted a lot of interest due to their outstanding properties both for hard and soft tissues. Here, for the f…
View article: Unexpected Absence of Skeletal Responses to Dietary Magnesium Depletion: Basis for Future Perspectives?
Unexpected Absence of Skeletal Responses to Dietary Magnesium Depletion: Basis for Future Perspectives? Open
It’s known that a magnesium (Mg)-deficient diet is associated with an increased risk of osteoporosis. The aim of this work is to investigate, by a histological approach, the effects of a Mg-deprived diet on the bone of 8-weeks-old C57BL/6J…
View article: Endoplasmic reticulum localization of phosphoinositide specific phospholipase C enzymes in U73122 cultured human osteoblasts
Endoplasmic reticulum localization of phosphoinositide specific phospholipase C enzymes in U73122 cultured human osteoblasts Open
Different signal transduction pathways contribute to the differentiation and metabolic activities of osteoblasts, with special regard to the calcium-related pathway of phosphoinositide specific phospholipase C (PLC) enzyme family. PLC enz…
View article: Editorial for the Special Issue on “Multidisciplinary Insights on Bone Healing”
Editorial for the Special Issue on “Multidisciplinary Insights on Bone Healing” Open
Animal and human bone damage can be considered differently according to a macro- or micro-level analysis [...]
View article: Pulsed Electro-Magnetic Field (PEMF) Effect on Bone Healing in Animal Models: A Review of Its Efficacy Related to Different Type of Damage
Pulsed Electro-Magnetic Field (PEMF) Effect on Bone Healing in Animal Models: A Review of Its Efficacy Related to Different Type of Damage Open
Biophysical energies are a versatile tool to stimulate tissues by generating biopotentials. In particular, pulsed electromagnetic field (PEMF) stimulation has intrigued researchers since the 1970s. To date, many investigations have been ca…
View article: Calcium Hydroxide Removal Using Four Different Irrigation Systems: A Quantitative Evaluation by Scanning Electron Microscopy
Calcium Hydroxide Removal Using Four Different Irrigation Systems: A Quantitative Evaluation by Scanning Electron Microscopy Open
This study compares conventional endodontic needle irrigation, passive ultrasonic irrigation, apical negative pressure irrigation, and mechanical activation to remove calcium hydroxide from single straight root canals. Eighty-four mandibul…
View article: Three-Punch Alveolar Ridge Reconstruction Technique: A Novel Flapless Approach in Eight Consecutive Cases
Three-Punch Alveolar Ridge Reconstruction Technique: A Novel Flapless Approach in Eight Consecutive Cases Open
This clinical and histologic case series aims to evaluate a novel flapless approach to alveolar ridge reconstruction (ARR) of compromised extraction sockets by means of collagenated xenograft sealed with three resorbable layers of hole-pun…
View article: Evaluation of the root filling quality with experimental carrier‐based obturators: a CLSM and FEG‐SEM analysis
Evaluation of the root filling quality with experimental carrier‐based obturators: a CLSM and FEG‐SEM analysis Open
This study evaluated tubule penetration of GuttaFlow Bioseal with cold single cone or carrier‐based technique, under confocal laser scanning microscopy (CLSM). Twenty straight single‐rooted teeth were instrumented with Hyflex CM and divide…
View article: Comparative Evaluation of the Penetration Depth into Dentinal Tubules of Three Endodontic Irrigants
Comparative Evaluation of the Penetration Depth into Dentinal Tubules of Three Endodontic Irrigants Open
This study aimed to examine the penetration depth into dentinal tubules of some chelating agents. The 17% EDTA and two preparations containing surfactants (Smear Clear, Bioakt Endo) were tested. Surface tension and liquid viscosity were me…
View article: Identification of Sclerostin as a Putative New Myokine Involved in the Muscle-to-Bone Crosstalk
Identification of Sclerostin as a Putative New Myokine Involved in the Muscle-to-Bone Crosstalk Open
Bone and muscle have been recognized as endocrine organs since they produce and secrete “hormone-like factors” that can mutually influence each other and other tissues, giving rise to a “bone–muscle crosstalk”. In our study, we made use of…
View article: Bone Healing Evaluation Following Different Osteotomic Techniques in Animal Models: A Suitable Method for Clinical Insights
Bone Healing Evaluation Following Different Osteotomic Techniques in Animal Models: A Suitable Method for Clinical Insights Open
Osteotomy is a common step in oncological, reconstructive, and trauma surgery. Drilling and elevated temperature during osteotomy produce thermal osteonecrosis. Heat and associated mechanical damage during osteotomy can impair bone healing…
View article: Volumetric Changes Following Lateral Guided Bone Regeneration
Volumetric Changes Following Lateral Guided Bone Regeneration Open
Resorbable membranes are well described and employed for horizontal guided bone regeneration (GBR). However, the currently available literature does not provide information on the bone volumetric changes during the healing that follows GBR…
View article: WISP-2 expression induced by Teriparatide treatment affects in vitro osteoblast differentiation and improves in vivo osteogenesis
WISP-2 expression induced by Teriparatide treatment affects in vitro osteoblast differentiation and improves in vivo osteogenesis Open
View article: Interaction among Calcium Diet Content, PTH (1-34) Treatment and Balance of Bone Homeostasis in Rat Model: The Trabecular Bone as Keystone
Interaction among Calcium Diet Content, PTH (1-34) Treatment and Balance of Bone Homeostasis in Rat Model: The Trabecular Bone as Keystone Open
The present study is the second step (concerning normal diet restoration) of the our previous study (concerning the calcium-free diet) to determine whether normal diet restoration, with/without concomitant PTH (1-34) administration, can in…
View article: Interplay among calcium diet content, PTH(1-34) treatment and balance of bone homeostases in rat model: the trabecular bone as keystone
Interplay among calcium diet content, PTH(1-34) treatment and balance of bone homeostases in rat model: the trabecular bone as keystone Open
The present study is the second step (concerning the normal-diet restoration) of the our previous one (concerning the calcium-free diet) to determine whether the normal-diet restoration, with/without concomitant PTH(1-34) administration, c…
View article: Sodium hypochlorite penetration into dentinal tubules after manual dynamic agitation and ultrasonic activation: a histochemical evaluation
Sodium hypochlorite penetration into dentinal tubules after manual dynamic agitation and ultrasonic activation: a histochemical evaluation Open
View article: Interaction between mineral and skeletal homeostasis in rats fed different calcium content diets with/without PTH (1-34)
Interaction between mineral and skeletal homeostasis in rats fed different calcium content diets with/without PTH (1-34) Open
Aim of the study is to analyze how mineral and skeletal homeostases influence both the bone loss due to calcium-diet deprivation and the successive bone mass recovery after calcium-diet restoration, with/without concomitant PTH(1-34) admin…
View article: Structural and ultrastructural analyses of bone regeneration in rabbit cranial osteotomy: Piezosurgery versus traditional osteotomes
Structural and ultrastructural analyses of bone regeneration in rabbit cranial osteotomy: Piezosurgery versus traditional osteotomes Open
View article: Preliminary observations on scleral ossicles in performing functionalized 3D vascularized scaffolds for “critical-size” bone defect healing
Preliminary observations on scleral ossicles in performing functionalized 3D vascularized scaffolds for “critical-size” bone defect healing Open
The problem of “critical-size” bone defects occurs when a severe lesion is difficult to be self-recovered. Many strategies of regenerative medicine were used in the last decade, with translational approaches, to mimic both structure and fu…
View article: Comparative morphological study of bone regeneration in different rabbit cranial osteotomies: traditional versus new generation osteotomes
Comparative morphological study of bone regeneration in different rabbit cranial osteotomies: traditional versus new generation osteotomes Open
The aim of this study was to compare the bone regeneration after skull surgery by means of different recent osteotomy devices, piezosurgery medical (PM) and piezosurgery medical plus (PMP), versus a conventional rotary osteotomy device (OT…
View article: Scleral ossicles as natural biomaterials on which vascular-like network is promoted from Mouse Aortic Endothelial cells (MAECs): preliminary results
Scleral ossicles as natural biomaterials on which vascular-like network is promoted from Mouse Aortic Endothelial cells (MAECs): preliminary results Open
When a severe fracture is difficult to self-recovered, it is defined as “critical-size” bone defect. Till now, many efforts have been made by the tissue engineering (TE) to generate scaffolds suitable for recovering of this type of fractur…
View article: Expression and functional proteomic analyses of osteocytes from <i>Xenopus laevis</i> tested under mechanical stress conditions: preliminary observations on an appropriate new animal model
Expression and functional proteomic analyses of osteocytes from <i>Xenopus laevis</i> tested under mechanical stress conditions: preliminary observations on an appropriate new animal model Open
Hitherto, the role of the osteocyte as transducer of mechanical stimuli into biological signals is far from settled. In this study, we used an appropriate model represented by the cortex of Xenopus laevis long bone diaphysis lacking (unlik…