Paola Saccomandi
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View article: AI-Enhanced Model for Integrated Performance Prediction and Classification of Vibration-Reducing Gloves for Hand-Transmitted Vibration Control
AI-Enhanced Model for Integrated Performance Prediction and Classification of Vibration-Reducing Gloves for Hand-Transmitted Vibration Control Open
This study presents a human-centric, data-driven modeling framework for the intelligent evaluation and classification of vibration-reducing (VR) gloves used in hand-transmitted vibration environments. Recognizing the trade-offs between pro…
View article: Improving soft tissue laser ablation outcomes: A Markov chain Monte Carlo-based approach
Improving soft tissue laser ablation outcomes: A Markov chain Monte Carlo-based approach Open
Laser ablation (LA) is a minimally invasive cancer therapy that uses laser energy to selectively heat and destroy cancerous tissues while minimizing damage to surrounding healthy tissue. Accurate temperature predictions derived from mathem…
View article: Nanoparticles-enhanced fiber optic plasmonic sensor for trace-level detection of mercury (Hg2+) ions
Nanoparticles-enhanced fiber optic plasmonic sensor for trace-level detection of mercury (Hg2+) ions Open
Continuous release of heavy metal ions (HMIs) from industrial, mining, and domestic wastewater sources poses a serious threat to the environment and living organisms. Among HMIs, mercury (Hg2+) is particularly hazardous due to its high tox…
View article: Wearable and Thermal Drift-Compensated Monitoring System Based on Fiber Bragg Grating Sensors for a 3D-Printed Foot Prosthesis
Wearable and Thermal Drift-Compensated Monitoring System Based on Fiber Bragg Grating Sensors for a 3D-Printed Foot Prosthesis Open
Monitoring foot prostheses is essential, as their performance impacts users’ daily lives. Fiber Bragg Grating (FBG) sensors represent a gold standard in monitoring applications, but traditional optoelectronic units are too cumbersome for w…
View article: Correction to: Performance of an Anti-Phase Technology-Powered Microwave Ablation System on Ex Vivo Liver, Lung and Kidney: Analysis of Temperature Trend, Ablation Size and Sphericity
Correction to: Performance of an Anti-Phase Technology-Powered Microwave Ablation System on Ex Vivo Liver, Lung and Kidney: Analysis of Temperature Trend, Ablation Size and Sphericity Open
View article: Fiber Bragg Grating Thermometry and Post-Treatment Ablation Size Analysis of Radiofrequency Thermal Ablation on Ex Vivo Liver, Kidney and Lung
Fiber Bragg Grating Thermometry and Post-Treatment Ablation Size Analysis of Radiofrequency Thermal Ablation on Ex Vivo Liver, Kidney and Lung Open
Radiofrequency ablation (RFA) is a minimally invasive procedure that utilizes localized heat to treat tumors by inducing localized tissue thermal damage. The present study aimed to evaluate the temperature evolution and spatial distributio…
View article: Performance of an Anti-Phase Technology-Powered Microwave Ablation System on Ex Vivo Liver, Lung and Kidney: Analysis of Temperature Trend, Ablation Size and Sphericity
Performance of an Anti-Phase Technology-Powered Microwave Ablation System on Ex Vivo Liver, Lung and Kidney: Analysis of Temperature Trend, Ablation Size and Sphericity Open
View article: Thermal effects and biological response of breast and pancreatic cancer cells undergoing gold nanorod-assisted photothermal therapy
Thermal effects and biological response of breast and pancreatic cancer cells undergoing gold nanorod-assisted photothermal therapy Open
View article: Advancing laser ablation assessment in hyperspectral imaging through machine learning
Advancing laser ablation assessment in hyperspectral imaging through machine learning Open
View article: Thermal Response of Gold Nanorods-loaded Polymeric Hydrogels Under NIR Laser Exposure for Biomedical Applications
Thermal Response of Gold Nanorods-loaded Polymeric Hydrogels Under NIR Laser Exposure for Biomedical Applications Open
This work presents the synthesis and characterization of gold nanorods (GNRs)-loaded agarose-carbomer-hyaluronic acid (AC-HA) hydrogels intended for biomedical applications, such as drug delivery and tissue engineering. The GNRs were synth…
View article: A sensitivity analysis of laser thermotherapy efficacy in lung cancer treatment to the temperature dependence of thermal properties
A sensitivity analysis of laser thermotherapy efficacy in lung cancer treatment to the temperature dependence of thermal properties Open
Laser interstitial thermotherapy has shown potential in the treatment of inoperable lung cancers, which make up 70-80 % of all cases, thanks to the possibility of real-time ultrasound guidance, a fine introducer needle, and faster recovery…
View article: Characterization of the Laser-induced Thermal Outcome of Gold Nanorods-mediated Photothermal Therapy in Breast Cancer Cells
Characterization of the Laser-induced Thermal Outcome of Gold Nanorods-mediated Photothermal Therapy in Breast Cancer Cells Open
In this study, we devised the characterization of the thermal outcome of gold nanorods (AuNRs)-mediated photothermal therapy (PTT) in triple-negative murine 4T1 cell line, employed as a model of breast cancer. After examining the character…
View article: Fiber optic sensing for temperature control during laser ablation of cancer tissues
Fiber optic sensing for temperature control during laser ablation of cancer tissues Open
Laser Ablation (LA) is a minimally invasive tumor treatment, particularly valuable when conventional methods are unsuitable. LA utilizes laser energy delivered using an optical fiber, offering advantages like electromagnetic immunity and f…
View article: The new thermometry with light: fiber optic sensors and novel imaging technologies for monitoring thermal-based therapies for localized tumors
The new thermometry with light: fiber optic sensors and novel imaging technologies for monitoring thermal-based therapies for localized tumors Open
Thermal therapies are energy-based interventions that provide a minimally invasive treatment option for cancer patients who may not be surgical candidates. Being these therapies based on the increase of tissue temperature to achieve tumor …
View article: Editorial: Wearable sensors for the measurement of physiological signals: what about their measurement uncertainty?
Editorial: Wearable sensors for the measurement of physiological signals: what about their measurement uncertainty? Open
Editorial: Wearable sensors for the measurement of physiological signals: what about their measurement uncertainty?
View article: Combined Ferritin Nanocarriers with ICG for Effective Phototherapy Against Breast Cancer
Combined Ferritin Nanocarriers with ICG for Effective Phototherapy Against Breast Cancer Open
The strong PDT efficacy and peculiar Trojan horse-like mechanism, that we revealed for the first time in literature, confirmed the promising application of HFn-ICG in PDT.
View article: Advancements in Sensor Technologies and Control Strategies for Lower-Limb Rehabilitation Exoskeletons: A Comprehensive Review
Advancements in Sensor Technologies and Control Strategies for Lower-Limb Rehabilitation Exoskeletons: A Comprehensive Review Open
Lower-limb rehabilitation exoskeletons offer a transformative approach to enhancing recovery in patients with movement disorders affecting the lower extremities. This comprehensive systematic review delves into the literature on sensor tec…
View article: Optical signatures of thermal damage on ex-vivo brain, lung and heart tissues using time-domain diffuse optical spectroscopy
Optical signatures of thermal damage on ex-vivo brain, lung and heart tissues using time-domain diffuse optical spectroscopy Open
Thermal therapies treat tumors by means of heat, greatly reducing pain, post-operation complications, and cost as compared to traditional methods. Yet, effective tools to avoid under- or over-treatment are mostly needed, to guide surgeons …
View article: Non-Fourier Bioheat Transfer Analysis in Brain Tissue During Interstitial Laser Ablation: Analysis of Multiple Influential Factors
Non-Fourier Bioheat Transfer Analysis in Brain Tissue During Interstitial Laser Ablation: Analysis of Multiple Influential Factors Open
View article: Fiber Optic SPR Sensor Modified With Copper Oxide Nanoparticles for Highly Sensitive and Selective Detection of Dopamine
Fiber Optic SPR Sensor Modified With Copper Oxide Nanoparticles for Highly Sensitive and Selective Detection of Dopamine Open
In modern biomedical technology, the fabrication of high-performance sensors for dopamine detection is an important issue because dopamine is a major neurotransmitter and abnormal level of its concentration in the human body is accountable…
View article: Thermal Effects and Biological Response of Breast and Pancreatic Cancer Cells Undergoing Gold Nanorod-Assisted Photothermal Therapy
Thermal Effects and Biological Response of Breast and Pancreatic Cancer Cells Undergoing Gold Nanorod-Assisted Photothermal Therapy Open
View article: Hyperspectral Imaging Dataset for Laser Thermal Ablation Monitoring in Vital Organs
Hyperspectral Imaging Dataset for Laser Thermal Ablation Monitoring in Vital Organs Open
Objectives: The objective of the research was to use hyperspectral imaging (HSI) to detect thermal damage induced in vital organs (such as the liver, pancreas, and stomach) during laser thermal therapy. The experimental study was conducted…
View article: Hyperspectral Imaging Dataset for Laser Thermal Ablation Monitoring in Vital Organs
Hyperspectral Imaging Dataset for Laser Thermal Ablation Monitoring in Vital Organs Open
<p><strong>Objectives:</strong> The objective of the research was to use hyperspectral imaging (HSI) to detect thermal damage induced in vital organs (such as the liver, pancreas, and stomach) during laser thermal therapy…
View article: An anthropomorphic thyroid phantom for ultrasound‐guided radiofrequency ablation of nodules
An anthropomorphic thyroid phantom for ultrasound‐guided radiofrequency ablation of nodules Open
Background Needle‐based procedures, such as fine needle aspiration and thermal ablation, are often applied for thyroid nodule diagnosis and therapeutic purposes, respectively. With blood vessels and nerves nearby, these procedures can pose…
View article: Roadmap on optical sensors
Roadmap on optical sensors Open
Optical sensors and sensing technologies are playing a more and more important role in our modern world. From micro-probes to large devices used in such diverse areas like medical diagnosis, defence, monitoring of industrial and environmen…
View article: Measurement of Thermal Conductivity and Thermal Diffusivity of Porcine and Bovine Kidney Tissues at Supraphysiological Temperatures up to 93 °C
Measurement of Thermal Conductivity and Thermal Diffusivity of Porcine and Bovine Kidney Tissues at Supraphysiological Temperatures up to 93 °C Open
This experimental study aimed to characterize the thermal properties of ex vivo porcine and bovine kidney tissues in steady-state heat transfer conditions in a wider thermal interval (23.2–92.8 °C) compared to previous investigations limit…
View article: Preliminary Results of Laser Ablation during In Vivo Experiments: Comparison of Thermal Effects Obtained with Bare and Diffuser Tip Applicators
Preliminary Results of Laser Ablation during In Vivo Experiments: Comparison of Thermal Effects Obtained with Bare and Diffuser Tip Applicators Open
This work is a step towards the analysis of the effect of different laser applicator tips used for laser ablation of liver for in vivo experiments. As the thermal outcome of this minimally invasive treatment for tumors depends upon the int…
View article: Theoretical Estimation of Tissue Thermal Response and Associated Thermal Damage During Gold Nanorod-enhanced Photothermal Therapy of Tumors
Theoretical Estimation of Tissue Thermal Response and Associated Thermal Damage During Gold Nanorod-enhanced Photothermal Therapy of Tumors Open
In the present work, we implemented a computational framework of in vivo gold nanorod (GNR)-enhanced photothermal therapy (PTT) for tumor treatment. The temperature-dependent thermophysical properties of biological tissue and the optical p…
View article: Characterization of the Optical and Thermal Properties of Cardiac Tissue as a Function of Temperature
Characterization of the Optical and Thermal Properties of Cardiac Tissue as a Function of Temperature Open
In this work, we devised the first characterization of the optical and thermal properties of ex vivo cardiac tissue as a function of different selected temperatures, ranging from room temperature to hyperthermic and ablative temperatures. …
View article: An anthropomorphic thyroid phantom for ultrasound-guided radiofrequency ablation of nodules
An anthropomorphic thyroid phantom for ultrasound-guided radiofrequency ablation of nodules Open
Background: Needle-based procedures such as fine needle aspiration (FNA) and thermal ablation, are often applied for thyroid nodule diagnosis and therapeutic purposes, respectively. With blood vessels and nerves nearby, these procedures ca…